Brief Information of the Compound and Protein
Compound Name
9-cis retinoic acid
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PubChem ID
CID: 449171
SID: 14898408
Canonical SMILES
C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C=C\C(\C)=C\C(O)=O
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Compound Formula C20H28O2
Compound Structure
Protein Name
Retinoic acid receptor alpha
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group B
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Nuclear hormone receptor subfamily 1 group B member 1
Uniprot ID
P10276
Gene Name
RARA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 1 nM
   TI
   LI
   LO
   TS
CL000044 CV-1 Chlorocebus aethiops (Green monkey)  3
1
AC50 = 19 nM
   TI
   LI
   LO
   TS
2
EC50 = 191 nM
   TI
   LI
   LO
   TS
3
EC50 = 220 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 23 nM
2 EC50 = 45 nM
3 EC50 = 102 nM
4 EC50 = 191 nM
5 IC50 = 7 nM
6 Kd = 11 nM
7 Kd = 90 nM
8 Kd = 93 nM
9 Ki = 22.3 nM