Brief Information of the Compound and Protein
Compound Name
3-(3,5-Di-tert-butyl-4-hydroxy-benzylidene)-1-methoxy-pyrrolidin-2-one
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PubChem ID
CID: 6438164
SID: 14851061
Canonical SMILES
CON1CC\C(=C/c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)C1=O
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Compound Formula C20H29NO3
Compound Structure
Protein Name
Polyunsaturated fatty acid 5-lipoxygenase
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
P12527
Gene Name
ALOX5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000194 RBL-1 Rattus norvegicus (Rat)  2
1
IC50 = 560 nM
   TI
   LI
   LO
   TS
2
IC50 = 8100 nM
   TI
   LI
   LO
   TS