Brief Information of the Compound and Protein
Compound Name
4,8-Difluoro-1-oxo-1,2-dihydro-6H-pyrrolo[3,2,1-de]acridine-2-carboxylic acid pyridin-2-ylamide
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PubChem ID
CID: 14460025
Canonical SMILES
Fc1ccc2N3C(=O)C(C(=O)Nc4ccccn4)c4cc(F)cc(Cc2c1)c34
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Compound Formula C21H13F2N3O2
Compound Structure
Protein Name
Polyunsaturated fatty acid 5-lipoxygenase
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
P12527
Gene Name
ALOX5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000194 RBL-1 Rattus norvegicus (Rat)  1
1
IC50 = 1900 nM
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