Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(4-((2,4-diamino-5-methylquinazolin-6-ylamino)methyl)benzamido)pentanedioic acid
    Show/Hide
 PubChem ID
CID: 324351
Canonical SMILES
Cc1c(NCc2ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc2)ccc2nc(N)nc(N)c12
    Show/Hide
Compound Formula C22H24N6O5
Compound Structure
Protein Name
 Protein Info 
Dihydrofolate reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P00374
Gene Name
DHFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000341 WIL2
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 4.1 nM
   TI
   LI
   LO
   TS