General Information of the Protein
Protein ID
PT07271
Protein Name
DNA-binding protein Ikaros
Secondarily
Protein Name
Ikaros family zinc finger protein 1
Lymphoid transcription factor LyF-1
Gene Name
IKZF1
Secondarily
Gene Name
IK1
IKAROS
LYF1
ZNFN1A1
Sequence
MDADEGQDMSQVSGKESPPVSDTPDEGDEPMPIPEDLSTTSGGQQSSKSDRVVASNVKVETQSDEENGRACEMNGEECAEDLRMLDASGEKMNGSHRDQGSSALSGVGGIRLPNGKLKCDICGIICIGPNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSVGKPHKCGYCGRSYKQRSSLEEHKERCHNYLESMGLPGTLYPVIKEETNHSEMAEDLCKIGSERSLVLDRLASNVAKRKSSMPQKFLGDKGLSDTPYDSSASYEKENEMMKSHVMDQAINNAINYLGAESLRPLVQTPPGGSEVVPVISPMYQLHKPLAEGTPRSNHSAQDSAVENLLLLSKAKLVPSEREASPSNSCQDSTDTESNNEEQRSGLIYLTNHIAPHARNGLSLKEEHRAYDLLRAASENSQDALRVVSTSGEQMKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRFHMS
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Organism
Homo sapiens, Human
Protein Classification
Unclassified protein
Function
Transcription regulator of hematopoietic cell differentiation (PubMed:17934067). Binds gamma-satellite DNA (PubMed:17135265, PubMed:19141594). Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs) (By similarity). Function is isoform-specific and is modulated by dominant-negative inactive isoforms (PubMed:17135265, PubMed:17934067).
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Uniprot ID
Primary ID:
Q13422

Secondarily ID:
A4D260
B4E0Z1
D3DVM5
O00598
Q53XL2
Q69BM4
Q8WVA3
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Ensembl ID
ENSG00000185811
HGNC ID
HGNC:13176
Subcellular Location
Nucleus
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000362 , GripTite 293 MSR
 Cell Line Info 
Compound ID Compound Name Compound Formula
CP0968112
 Compound Info 
3-(1-oxo-5-(1-((2-phenylthiazol-4-yl)methyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C28H28N4O3S
  1
1
EC50 = 39 nM
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CP0965605
 Compound Info 
3-(1-oxo-5-(1-((4-phenyl-1H-imidazol-2-yl)methyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C28H29N5O3
  1
1
EC50 = 43 nM
 Bioactivity Info 
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CP0955081
 Compound Info 
3-(5-(1-(3-(tert-butyl)benzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C29H35N3O3
  1
1
EC50 = 140 nM
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CP0968031
 Compound Info 
3-((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperidin-1-yl)methyl)-N,N-dimethylbenzenesulfonamide
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C27H32N4O5S
  1
1
EC50 = 220 nM
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CP0951123
 Compound Info 
3-(5-(1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C25H25N3O3
  1
1
EC50 = 250 nM
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CP0968029
 Compound Info 
3-(5-(1-((6-isopropoxypyridin-2-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C27H32N4O4
  1
1
EC50 = 320 nM
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CP0950510
 Compound Info 
3-(5-(1-(isoquinolin-1-ylmethyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C28H28N4O3
  1
1
EC50 > 25000 nM
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CP0965585
 Compound Info 
3-(5-(1-(3-(morpholinosulfonyl)benzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C29H34N4O6S
  1
1
EC50 > 25000 nM
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CP0965592
 Compound Info 
3-(5-(1-((1H-indazol-5-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C26H27N5O3
  1
1
EC50 > 25000 nM
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CP0965593
 Compound Info 
3-(1-oxo-5-(1-(thiazol-4-ylmethyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C22H24N4O3S
  1
1
EC50 > 25000 nM
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CP0950511
 Compound Info 
3-((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperidin-1-yl)methyl)benzamide
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C26H28N4O4
  1
1
EC50 > 30000 nM
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CP0950512
 Compound Info 
3-(5-(1-((5-amino-1-methyl-1H-pyrazol-4-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C23H28N6O3
  1
1
EC50 > 30000 nM
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CP0950513
 Compound Info 
3-(5-(1-((1-cyclobutyl-1H-1,2,3-triazol-4-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C25H30N6O3
  1
1
EC50 > 30000 nM
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CP0950514
 Compound Info 
3-(1-oxo-5-(1-(pyrazolo[1,5-a]pyridin-4-ylmethyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C26H27N5O3
  1
1
EC50 > 30000 nM
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CP0950515
 Compound Info 
3-(5-(1-ethylpiperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C20H25N3O3
  1
1
EC50 > 30000 nM
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CP0950516
 Compound Info 
3-(1-oxo-5-(1-(3-(trifluoromethoxy)benzyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C26H26F3N3O4
  1
1
EC50 > 30000 nM
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CP0950517
 Compound Info 
3-(5-(1-(4-ethoxybenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C27H31N3O4
  1
1
EC50 > 30000 nM
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CP0950518
 Compound Info 
3-(5-(1-((1H-pyrazol-4-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C22H25N5O3
  1
1
EC50 > 30000 nM
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CP0950520
 Compound Info 
3-(1-oxo-5-(1-(quinoxalin-6-ylmethyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C27H27N5O3
  1
1
EC50 > 30000 nM
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CP0951096
 Compound Info 
3-(5-(1-(4-(5-methylbenzo[d]thiazol-2-yl)benzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C33H32N4O3S
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0951097
 Compound Info 
3-(5-(1-(4-(hydroxymethyl)benzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C26H29N3O4
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0951098
 Compound Info 
3-(5-(1-(3-fluoro-4-methylbenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C26H28FN3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0951099
 Compound Info 
3-(1-oxo-5-(1-((5-(trifluoromethyl)pyridin-2-yl)methyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C25H25F3N4O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0951100
 Compound Info 
3-(1-oxo-5-(1-(2-(trifluoromethyl)benzyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C26H26F3N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0951101
 Compound Info 
2-(4-((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperidin-1-yl)methyl)phenyl)acetic acid
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C27H29N3O5
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0951102
 Compound Info 
3-(5-(1-(3-(difluoromethyl)benzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C26H27F2N3O3
  1
1
EC50 > 30000 nM
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CP0951103
 Compound Info 
3-(5-(1-(benzo[d]thiazol-2-ylmethyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C26H26N4O3S
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0951104
 Compound Info 
3-(1-oxo-5-(1-((4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)methyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C25H25N5O4S
  1
1
EC50 > 30000 nM
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CP0951105
 Compound Info 
3-(5-(1-(2-fluoro-1-phenylethyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C26H28FN3O3
  1
1
EC50 > 30000 nM
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CP0951106
 Compound Info 
3-(5-(1-((3,4-dihydro-2H-benzo[b][1,4]thiazin-6-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C27H30N4O3S
  1
1
EC50 > 30000 nM
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CP0951107
 Compound Info 
3-(5-(1-((1H-indol-2-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C27H28N4O3
  1
1
EC50 > 30000 nM
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CP0951108
 Compound Info 
3-(5-(1-((5-cyclopropyl-1H-pyrazol-3-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C25H29N5O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0951113
 Compound Info 
3-(1-oxo-5-(1-((4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl)methyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C26H31N5O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0951114
 Compound Info 
3-(1-oxo-5-(1-((3-(pyridin-3-yl)-1H-pyrazol-4-yl)methyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C27H28N6O3
  1
1
EC50 > 30000 nM
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CP0951115
 Compound Info 
3-(5-(1-(cyclobutylmethyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C23H29N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0951116
 Compound Info 
3-(1-oxo-5-(1-((tetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C24H31N3O4
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0951117
 Compound Info 
3-(1-oxo-5-(1-(4-(trifluoromethoxy)benzyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C26H26F3N3O4
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0951118
 Compound Info 
3-(5-(1-(3,5-difluorobenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C25H25F2N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0951119
 Compound Info 
4-((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperidin-1-yl)methyl)benzoic Acid
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C26H27N3O5
  1
1
EC50 > 30000 nM
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CP0951120
 Compound Info 
4-((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperidin-1-yl)methyl)benzamide
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C26H28N4O4
  1
1
EC50 > 30000 nM
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CP0951121
 Compound Info 
3-(5-(1-benzyl-3,3-dimethylpiperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C27H31N3O3
  1
1
EC50 > 30000 nM
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CP0951122
 Compound Info 
3-(1-oxo-5-(1-(pyrimidin-2-ylmethyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C23H25N5O3
  1
1
EC50 > 30000 nM
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CP0951128
 Compound Info 
3-(5-(1-(4-(1H-pyrazol-1-yl)benzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C28H29N5O3
  1
1
EC50 > 30000 nM
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CP0951129
 Compound Info 
3-(5-(1-((1-methyl-1H-indazol-3-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C27H29N5O3
  1
1
EC50 > 30000 nM
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CP0951130
 Compound Info 
3-(5-(1-((7-fluoroquinolin-2-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C28H27FN4O3
  1
1
EC50 > 30000 nM
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CP0951131
 Compound Info 
3-(5-(1-((6-methyl-1H-indol-3-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C28H30N4O3
  1
1
EC50 > 30000 nM
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CP0951132
 Compound Info 
3-(5-(1-(benzo[d]thiazol-5-ylmethyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C26H26N4O3S
  1
1
EC50 > 30000 nM
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CP0951267
 Compound Info 
3-(5-(1-(3-isopropoxybenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C28H33N3O4
  1
1
EC50 > 30000 nM
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CP0951270
 Compound Info 
3-(5-(1-(4-cyclopentylbenzyl)piperidin-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C30H35N3O3
  1
1
EC50 > 30000 nM
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CP0951272
 Compound Info 
3-(1-oxo-5-(1-(4-(tert-pentyl)benzyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C30H37N3O3
  1
1
EC50 > 30000 nM
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CP0954467
 Compound Info 
3-(5-(1-((7-hydroxy-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C26H28N6O4
  1
1
EC50 > 30000 nM
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CP0955080
 Compound Info 
methyl2-((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperidin-1-yl)methyl)oxazole-4-carboxylate
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C24H26N4O6
  1
1
EC50 > 30000 nM
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CP0955098
 Compound Info 
3-((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperidin-1-yl)methyl)benzoic acid
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C26H27N3O5
  1
1
EC50 > 30000 nM
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CP0959276
 Compound Info 
4-((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperidin-1-yl)methyl)-N,N-dimethylbenzenesulfonamide
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C27H32N4O5S
  1
1
EC50 > 30000 nM
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CP0959277
 Compound Info 
3-(5-(1-((5-methyl-3-phenylisoxazol-4-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C29H30N4O4
  1
1
EC50 > 30000 nM
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CP0960541
 Compound Info 
3-(5-(1-(3-(difluoromethoxy)benzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C26H27F2N3O4
  1
1
EC50 > 30000 nM
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CP0960542
 Compound Info 
3-(5-(1-(2,5-difluorobenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C25H25F2N3O3
  1
1
EC50 > 30000 nM
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CP0960543
 Compound Info 
3-(1-oxo-5-(1-(4-(pyridin-2-ylmethoxy)benzyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C31H32N4O4
  1
1
EC50 > 30000 nM
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CP0960544
 Compound Info 
3-(5-(1-(4-(fluoromethyl)benzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C26H28FN3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0960545
 Compound Info 
3-(5-(1-(naphthalen-2-ylmethyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C29H29N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0960546
 Compound Info 
3-(5-(1-((2-aminopyrimidin-5-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C23H26N6O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0960547
 Compound Info 
N-(4-((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperidin-1-yl)methyl)phenyl)acetamide
   Show/Hide
C27H30N4O4
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0960548
 Compound Info 
3-(5-(1-((6-methylimidazo[2,1-b]thiazol-5-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C25H27N5O3S
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0960549
 Compound Info 
3-(1-oxo-5-(1-((3-(pyridin-2-yl)-1H-pyrazol-5-yl)methyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C27H28N6O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0960551
 Compound Info 
2-(4-((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperidin-l-yl)methyl)phenyl)acetonitrile
   Show/Hide
C27H28N4O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0960552
 Compound Info 
3-(1-oxo-5-(1-((2-(pyrrolidin-1-yl)pyrimidin-5-yl)methyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C27H32N6O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0960757
 Compound Info 
3-(5-(1-(2,4-dichlorobenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C25H25Cl2N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0960758
 Compound Info 
3-(5-(1-(2,4-difluorobenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C25H25F2N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0964072
 Compound Info 
3-(5-(1-(4-(difluoromethyl)benzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C26H27F2N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0964073
 Compound Info 
3-(5-(1-([1,2,4]triazolo[1,5-a]pyridin-5-ylmethyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C25H26N6O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0964074
 Compound Info 
3-(5-(1-((2-morpholinopyrimidin-5-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C27H32N6O4
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0964111
 Compound Info 
3-(5-(1-isobutylpiperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C22H29N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0964112
 Compound Info 
3-(1-oxo-5-(1-((S)-1-phenylethyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C26H29N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0965583
 Compound Info 
3-(5-(1-(3,4-difluorobenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C25H25F2N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0965584
 Compound Info 
3-((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperidin-1-yl)methyl)benzonitrile
   Show/Hide
C26H26N4O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0965586
 Compound Info 
3-(5-(1-(2-cyclopropylbenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C28H31N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0965587
 Compound Info 
3-(5-(1-(4-(4-methoxypiperidin-1-yl)benzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C31H38N4O4
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0965588
 Compound Info 
3-(5-(1-(2,6-difluorobenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C25H25F2N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0965589
 Compound Info 
3-(5-(1-(2-(difluoromethoxy)benzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C26H27F2N3O4
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0965590
 Compound Info 
3-(5-(1-(3-chlorobenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C25H26ClN3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0965591
 Compound Info 
3-(5-(1-(4-isopropylbenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C28H33N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0965594
 Compound Info 
3-(5-(1-(2,2-difluoro-1-phenylethyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C26H27F2N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0965595
 Compound Info 
3-(5-(1-((1,4-dimethyl-1H-imidazol-2-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C24H29N5O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0965596
 Compound Info 
3-(1-oxo-5-(1-((2-oxo-2,3-dihydro-1H-benz[d]imidazol-5-yl)methyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C26H27N5O4
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0965597
 Compound Info 
3-(1-oxo-5-(1-((3-phenyl-1H-pyrazol-4-yl)methyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C28H29N5O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0965598
 Compound Info 
3-(5-(1-((2-(tert-butyl)thiazol-4-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C26H32N4O3S
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0965599
 Compound Info 
3-(5-(1-((1-methyl-1H-pyrazol-3-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C23H27N5O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0965600
 Compound Info 
3-(1-oxo-5-(1-(3,3,3-trifluoropropyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C21H24F3N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0965601
 Compound Info 
3-(1-oxo-5-(1-((1-phenyl-1H-pyrazol-4-yl)methyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C28H29N5O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0965603
 Compound Info 
3-(5-((S)-1-benzylazepan-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C26H29N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0965604
 Compound Info 
NA3-(5-(1-benzyl-2,5-dihydro-1H-pyrrol-3-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C24H23N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0966494
 Compound Info 
3-(5-(1-((2-chlorothiazol-5-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C22H23ClN4O3S
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0966495
 Compound Info 
6-((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperidin-1-yl)methyl)picolinonitrile
   Show/Hide
C25H25N5O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0966496
 Compound Info 
3-(1-oxo-5-(1-(pyridin-3-ylmethyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C24H26N4O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0966497
 Compound Info 
3-(5-(1-(cyclopropylmethyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C22H27N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0966498
 Compound Info 
3-(5-(1-((R)-2-hydroxy-1-phenylethyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C26H29N3O4
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0966499
 Compound Info 
3-(5-(1-((S)-2-hydroxy-1-phenylethyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C26H29N3O4
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0966500
 Compound Info 
3-(5-(1-((6-isopropoxyl)pyridin-3-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C27H32N4O4
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0966501
 Compound Info 
3-(5-((R)-1-benzylazepan-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C26H29N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0966502
 Compound Info 
3-(1-oxo-5-(1,2,5,6-tetrahydropyridin-3-yl)isoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C18H19N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0966504
 Compound Info 
3-(5-(1-((1H-indazol-6-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C26H27N5O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0967208
 Compound Info 
3-(5-(1-((3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C28H31N3O5
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0967209
 Compound Info 
3-(5-(1-(4-(difluoromethoxy)benzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C26H27F2N3O4
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0967210
 Compound Info 
3-(5-(1-(4-(isopropylthio)benzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C28H33N3O3S
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0967211
 Compound Info 
3-(5-(1-(3,5-bis(trifluoromethyl)benzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C27H25F6N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0967212
 Compound Info 
3-(5-(1-(4-(tert-butyl)benzoyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C29H33N3O4
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0967213
 Compound Info 
3-(1-oxo-5-(1-(pyridin-2-ylmethyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C24H26N4O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0968023
 Compound Info 
3-(5-(1-((6-aminopyridin-3-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C24H27N5O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0968024
 Compound Info 
3-(5-(1-benzyl-3-methylpiperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C26H29N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0968025
 Compound Info 
3-(1-oxo-5-(1-phenethylpiperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C26H29N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0968026
 Compound Info 
3-(1-oxo-5-(1-((R)-1-phenylethyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C26H29N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0968027
 Compound Info 
3-(1-oxo-5-(1-((1-phenyl-1H-pyrazol-5-yl)methyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C28H29N5O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0968028
 Compound Info 
3-(5-(1-benzylpyrrolidin-3-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione formate
   Show/Hide
C25H27N3O5
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0968030
 Compound Info 
3-(5-(1((1H-indazol-4-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C26H27N5O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0968079
 Compound Info 
3-(5-(1-(isothiazol-5-ylmethyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C22H24N4O3S
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0968127
 Compound Info 
3-(1-oxo-5-(1-(4-(trifluoromethyl)benzyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C26H26F3N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0968128
 Compound Info 
3-(5-(1-((1-ethyl-1H-pyrazol-3-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C24H29N5O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0968176
 Compound Info 
3-(5-(1-(2-methoxybenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C26H29N3O4
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0968228
 Compound Info 
3-(5-(1-(naphthalen-1-ylmethyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C29H29N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0968229
 Compound Info 
3-(5-(1-(2-chlorobenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C25H26ClN3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0968670
 Compound Info 
3-(5-(1-(4-(methoxymethyl)benzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C27H31N3O4
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0968671
 Compound Info 
3-(5-(1-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C26H25F2N3O5
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0968672
 Compound Info 
3-(5-(1-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
   Show/Hide
C27H29N3O5
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0968673
 Compound Info 
2-(4-((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperidin-1-yl)methyl)phenoxy)acetonitrile
   Show/Hide
C27H28N4O4
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0968675
 Compound Info 
3-((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperidin-1-yl)methyl)-1,2,4-oxadiazole-5-carboxamide
   Show/Hide
C22H24N6O5
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0968676
 Compound Info 
3-(5-(1-((1-methyl-1H-pyrazol-4-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C23H27N5O3
  1
1
EC50 > 30000 nM
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CP0968677
 Compound Info 
3-(5-(1-((1H-pyrrol-3-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C23H26N4O3
  1
1
EC50 > 30000 nM
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CP0968765
 Compound Info 
3-(5-(1-(imidazo[1,2-a]pyrazin-3-ylmethyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C25H26N6O3
  1
1
EC50 > 30000 nM
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CP0968766
 Compound Info 
3-(5-(1-(4-hydroxy-3-((4-methylpiperazin-1-yl)methyl)benzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C31H39N5O4
  1
1
EC50 > 30000 nM
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CP0969277
 Compound Info 
3-(5-(1-((2-amino-4-(trifluoromethyl)thiazol-5-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C23H24F3N5O3S
  1
1
EC50 > 30000 nM
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CP0969290
 Compound Info 
3-(5-(1-(imidazo[1,2-a]pyrimidin-3-ylmethyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C25H26N6O3
  1
1
EC50 > 30000 nM
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CP0969291
 Compound Info 
3-(5-(1-((1H-imidazol-5-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C22H25N5O3
  1
1
EC50 > 30000 nM
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CP0969566
 Compound Info 
3-(5-(1-((1H-pyrrolo[2,3-b]pyridin-6-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C26H27N5O3
  1
1
EC50 > 30000 nM
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CP0969601
 Compound Info 
3-(5-(1-(3-methylbenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C26H29N3O3
  1
1
EC50 > 30000 nM
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CP0969941
 Compound Info 
3-(5-(1-(4-((difluoromethyl)sulfonyl)benzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C26H27F2N3O5S
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0969942
 Compound Info 
3-(5-(1-(4-(tert-butyl)benzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione formate
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C30H37N3O5
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0969943
 Compound Info 
3-(5-(1-(2,4-dimethylbenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C27H31N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0969944
 Compound Info 
3-(5-(1-((1-isopropyl-1H-pyrazol-5-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C25H31N5O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0970130
 Compound Info 
2-((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperidin-1-yl)methyl)benzonitrile
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C26H26N4O3
  1
1
EC50 > 30000 nM
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CP0970263
 Compound Info 
3-(5-(1-((2,3-dihydrobenzo[b][1,4]dioxin-5-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C27H29N3O5
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0970265
 Compound Info 
3-(5-(1-(4-ethylbenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C27H31N3O3
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0970296
 Compound Info 
3-(1-oxo-5-(1-(4-propylbenzyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C28H33N3O3
  1
1
EC50 > 30000 nM
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CP0970297
 Compound Info 
3-(5-(1-(4-((4-fluorobenzyl)oxy)benzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C32H32FN3O4
  1
1
EC50 > 30000 nM
 Bioactivity Info 
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CP0950502
 Compound Info 
3-(5-((R)-azepan-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C19H23N3O3
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0950503
 Compound Info 
3-(1-oxo-5-(1-phenylpiperidin-4-yl)isoindolin-2-yl)piperidine-26-dione
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C24H25N3O3
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0950504
 Compound Info 
3-(5-(1-(cyclohexylmethyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C25H33N3O3
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0950505
 Compound Info 
3-(5-(1-(2-methylbenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C26H29N3O3
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0950506
 Compound Info 
3-(5-(1-(4-cyanobenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C26H26N4O3
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0950507
 Compound Info 
3-(1-oxo-5-(1-((5,6,7,8-tetrahydronaphthalen-2-yl)methyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C29H33N3O3
  1
1
EC50 > 50000 nM
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CP0950509
 Compound Info 
3-(5-(1-(isoxazol-3-ylmethyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C22H24N4O4
  1
1
EC50 > 50000 nM
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CP0950519
 Compound Info 
3-(5-(1-(4-methoxybenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione formate
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C27H31N3O6
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0951124
 Compound Info 
methyl 2-(4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperidin-1-yl)acetate
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C21H25N3O5
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0951125
 Compound Info 
3-(5-(1-benzylpiperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C25H27N3O3
  1
1
EC50 > 50000 nM
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CP0951126
 Compound Info 
3-(5-(1-(4-methylbenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C26H29N3O3
  1
1
EC50 > 50000 nM
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CP0951127
 Compound Info 
3-(5-(1-(3,5-difluoro-4-hydroxybenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C25H25F2N3O4
  1
1
EC50 > 50000 nM
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CP0951268
 Compound Info 
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione Hydrochloride
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C18H22ClN3O3
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0951269
 Compound Info 
3-(1-oxo-5-(1-((5,6,7,8-tetrahydronaphthalen-1-yl)methyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C29H33N3O3
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0954468
 Compound Info 
rac 3-(1-oxo-5-(1-(1-phenylethyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C26H29N3O3
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0954469
 Compound Info 
3-(5-(1-(4-fluorobenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione formate
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C26H28FN3O5
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0955079
 Compound Info 
3-(5-(1-((3-methylisoxazol-5-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C23H26N4O4
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0960550
 Compound Info 
3-(5-((2S)-1-benzyl-2-methylpiperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione formate
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C27H31N3O5
  1
1
EC50 > 50000 nM
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CP0960759
 Compound Info 
3-(1-oxo-5-(1-(2,2,2-trifluoro-1-phenylethyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione formate
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C27H28F3N3O5
  1
1
EC50 > 50000 nM
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CP0964110
 Compound Info 
3-(5-((S)-azepan-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C19H23N3O3
  1
1
EC50 > 50000 nM
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CP0965602
 Compound Info 
3-(1-oxo-5-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C20H22F3N3O3
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0965980
 Compound Info 
3-(5-(1-([1,1'-biphenyl]-4-ylmethyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C31H31N3O3
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0966466
 Compound Info 
3-(5-(1-(3,5-dimethylbenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C27H31N3O3
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0966503
 Compound Info 
tert-butyl 2-(4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperidin-1-yl)acetate
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C24H31N3O5
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0968022
 Compound Info 
3-(1-oxo-5-(1-(quinolin-4-ylmethyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C28H28N4O3
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0968111
 Compound Info 
3-(5-(1-((2-methoxypyrimidin-5-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C24H27N5O4
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0968222
 Compound Info 
3-(5-(1-(4-chlorobenzyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C25H26ClN3O3
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0968474
 Compound Info 
3-(5-(1-((1H-pyrazol-3-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C22H25N5O3
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0968674
 Compound Info 
3-(5-(1-((7-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C28H29N5O4
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0968764
 Compound Info 
3-(1-oxo-5-(1-(quinolin-8-ylmethyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C28H28N4O3
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0969278
 Compound Info 
3-(5-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C19H21N3O3
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0969279
 Compound Info 
3-(1-oxo-5-(1-((1,2,3,4-tetrahydronaphthalen-1-yl)methyl)piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione
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C29H33N3O3
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0969671
 Compound Info 
NA3-(5-(8-benzyl-8-azabicyclo[3.2.1]octan-3-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione formate
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C28H31N3O5
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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CP0970501
 Compound Info 
3-(5-(1-((1,2,4-oxadiazol-3-yl)methyl)piperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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C21H23N5O4
  1
1
EC50 > 50000 nM
 Bioactivity Info 
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