General Information of the Protein
| Protein ID |
PT06859
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| Protein Name |
Dual specificity protein phosphatase 2
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| Secondarily Protein Name |
Dual specificity protein phosphatase PAC-1
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| Gene Name |
DUSP2
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| Secondarily Gene Name |
PAC1
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| Sequence |
MGLEAARELECAALGTLLRDPREAERTLLLDCRPFLAFCRRHVRAARPVPWNALLRRRARGPPAAVLACLLPDRALRTRLVRGELARAVVLDEGSASVAELRPDSPAHVLLAALLHETRAGPTAVYFLRGGFDGFQGCCPDLCSEAPAPALPPTGDKTSRSDSRAPVYDQGGPVEILPYLFLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQVLCH
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| Organism |
Homo sapiens, Human
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| Protein Classification |
Enzyme
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Phosphatase
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Protein Phosphatase
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Serine/threonine/tyrosine protein phosphatase
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| Function |
Dephosphorylates both phosphorylated Thr and Tyr residues in MAPK1, and dephosphorylation of phosphotyrosine is slightly faster than that of phosphothreonine (PubMed:8107850). Can dephosphorylate MAPK1 (By similarity).
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| Uniprot ID |
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| HGNC ID | |||||
| Subcellular Location |
Nucleus
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Map of Molecular Bioactivity Related to the Protein
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Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Protein
