General Information of the Protein
Protein ID
PT06508
Protein Name
P2Y purinoceptor 2
Secondarily
Protein Name
ATP receptor
P2U purinoceptor 1
Purinergic receptor
Gene Name
P2RY2
Secondarily
Gene Name
P2ru1
Sequence
MAADLEPWNSTINGTWEGDELGYKCRFNEDFKYVLLPVSYGVVCVLGLCLNVVALYIFLCRLKTWNASTTYMFHLAVSDSLYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLHSLRWGRARYARRVAAVVWVLVLACQAPVLYFVTTSVRGTRITCHDTSARELFSHFVAYSSVMLGLLFAVPFSVILVCYVLMARRLLKPAYGTTGGLPRAKRKSVRTIALVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKITRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTEPTPSPQARRKLGLHRPNRTVRKDLSVSSDDSRRTESTPAGSETKDIRL
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Organism
Mus musculus, Mouse
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Nucleotide-like receptor (family A GPCR)
>
Purine receptor
Function
Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP.
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Uniprot ID
Primary ID:
P35383

Secondarily ID:
O09031
Q9CPZ4
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Ensembl ID
ENSG00000175591
Subcellular Location
Cell membrane
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000047 , 108CC15
 Cell Line Info 
Compound ID Compound Name Compound Formula
CP0652101
 Compound Info 
Reactive Blue-2
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C29H17ClN7Na3O11S3
  1
1
IC50 = 5000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0655729
 Compound Info 
sodium 1-amino-4-(2-methoxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
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C21H15N2NaO6S
  1
1
IC50 = 9000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0854361
 Compound Info 
sodium 1-amino-4-(4-ethoxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
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C22H17N2NaO6S
  1
1
IC50 = 9000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0854848
 Compound Info 
sodium 1-amino-4-(2,4-dimethylphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
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C22H17N2NaO5S
  1
1
IC50 = 9000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0878493
 Compound Info 
sodium 1-amino-9,10-dioxo-4-(o-tolylamino)-9,10-dihydroanthracene-2-sulfonate
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C21H15N2NaO5S
  1
1
IC50 = 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0652102
 Compound Info 
sodium 1-amino-9,10-dioxo-4-(phenylamino)-9,10-dihydroanthracene-2-sulfonate
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C20H13N2NaO5S
  1
1
IC50 = 11100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0880743
 Compound Info 
sodium 4-(4-acetamidophenylamino)-1-amino-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
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C22H16N3NaO6S
  1
1
IC50 = 12000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0878492
 Compound Info 
sodium 1-amino-4-(2,3-dimethylphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
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C22H17N2NaO5S
  1
1
IC50 = 14000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0785160
 Compound Info 
sodium 1-amino-4-(4-methoxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
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C21H15N2NaO6S
  1
1
IC50 = 17000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0846903
 Compound Info 
Sodium 1-Amino-4-(2,5-dimethylphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
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C22H17N2NaO5S
  1
1
IC50 = 17000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0887291
 Compound Info 
Sodium 1-amino-4-(2-ethoxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
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C22H17N2NaO6S
  1
1
IC50 = 17000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0791547
 Compound Info 
SID50112916
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C20H12ClN2NaO5S
  1
1
IC50 = 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0849078
 Compound Info 
sodium 1-amino-9,10-dioxo-4-(m-tolylamino)-9,10-dihydroanthracene-2-sulfonate
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C21H15N2NaO5S
  1
1
IC50 = 22000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0854449
 Compound Info 
sodium 1-amino-4-(2-ethylphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
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C22H17N2NaO5S
  1
1
IC50 = 24000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0874900
 Compound Info 
sodium 1-amino-9,10-dioxo-4-(p-tolylamino)-9,10-dihydroanthracene-2-sulfonate
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C21H15N2NaO5S
  1
1
IC50 = 27000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0874902
 Compound Info 
sodium 1-amino-9,10-dioxo-4-(4-(phenylamino)phenylamino)-9,10-dihydroanthracene-2-sulfonate
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C26H18N3NaO5S
  1
1
IC50 = 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0878490
 Compound Info 
sodium 1-amino-4-(3-nitrophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
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C20H12N3NaO7S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0878491
 Compound Info 
sodium 4-(4-acetylphenylamino)-1-amino-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
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C22H15N2NaO6S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0878494
 Compound Info 
sodium 1-amino-4-bromo-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
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C14H7BrNNaO5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
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   TS
CP0929924
 Compound Info 
sodium 1-amino-4-(3-chlorophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
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C20H12ClN2NaO5S
  1
1
IC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Cell Line ID: CL000094 , 1321N1
 Cell Line Info 
Similar Protein(s) and Bioactivity Statistics
90% Identity
Protein ID Protein Name Protein Organism
PT04714 P2Y purinoceptor 2 Homo sapiens, Human
 Protein Info