General Information of the Protein
Protein ID
PT06396
Protein Name
Putative P2Y purinoceptor 10
Secondarily
Protein Name
P2Y-like receptor
Gene Name
P2RY10
Sequence
MANLDKYTETFKMGSNSTSTAEIYCNVTNVKFQYSLYATTYILIFIPGLLANSAALWVLCRFISKKNKAIIFMINLSVADLAHVLSLPLRIYYYISHHWPFQRALCLLCFYLKYLNMYASICFLTCISLQRCFFLLKPFRARDWKRRYDVGISAAIWIVVGTACLPFPILRSTDLNNNKSCFADLGYKQMNAVALVGMITVAELAGFVIPVIIIAWCTWKTTISLRQPPMAFQGISERQKALRMVFMCAAVFFICFTPYHINFIFYTMVKETIISSCPVVRIALYFHPFCLCLASLCCLLDPILYYFMASEFRDQLSRHGSSVTRSRLMSKESGSSMIG
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Organism
Homo sapiens, Human
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
Function
Putative receptor for purines coupled to G-proteins.
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Uniprot ID
Primary ID:
O00398

Secondarily ID:
D3DTE5
Q4VBN7
Q86V16
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Ensembl ID
ENSG00000078589
HGNC ID
HGNC:19906
Subcellular Location
Cell membrane
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000050 , HEK293-A
Compound ID Compound Name Compound Formula
CP0386278
(2S)-2-amino-3-[[(2S)-2-fluoro-3-[(Z)-octadec-9-enoyl]oxypropoxy]-hydroxyphosphoryl]oxypropanoic acid
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C24H45FNO8P
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0388868
[(2R)-3-[[(2R)-2-amino-3-hydroxypropoxy]-hydroxyphosphoryl]oxy-2-hydroxypropyl] (Z)-octadec-9-enoate
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C24H48NO8P
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0388871
(2S)-2-amino-3-[[(2R)-3-decanoyloxy-2-hydroxypropoxy]-hydroxyphosphoryl]oxypropanoic acid
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C16H32NO9P
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0388872
(2R)-2-amino-3-[hydroxy-[(2R)-2-hydroxy-3-[(Z)-octadec-9-enoyl]oxypropoxy]phosphoryl]oxypropanoic acid
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C24H46NO9P
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0406328
(2S)-2-amino-3-[hydroxy-[(2R)-2-methoxy-3-[(Z)-octadec-9-enoyl]oxypropoxy]phosphoryl]oxypropanoic acid
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C25H48NO9P
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0420416
(2S,3S)-2-amino-3-[hydroxy-[(2R)-2-hydroxy-3-[(Z)-octadec-9-enoyl]oxypropoxy]phosphoryl]oxybutanoic acid
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C25H48NO9P
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0450597
(2S,3S)-2-amino-3-[[(2R)-3-[3-(3-heptoxyphenyl)propanoyloxy]-2-hydroxypropoxy]-hydroxyphosphoryl]oxybutanoic acid
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C23H38NO10P
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
CP0450598
(2S,3S)-2-amino-3-[hydroxy-[(2R)-2-hydroxy-3-[3-(3-undecoxyphenyl)propanoylamino]propoxy]phosphoryl]oxybutanoic acid
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C27H47N2O9P
 1
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
Clinical Information about the Protein
Target 1 ( P2Y purinoceptor 10 (P2RY10) )
Target Type Literature-reported Target