| Compound ID |
Compound Name |
Compound Formula |
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CP0411581
|
1-[[1-(4-fluorophenyl)-5-(2-methoxyphenyl)pyrazole-3-carbonyl]amino]cyclohexane-1-carboxylic acid
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|
C24H24FN3O4
|
4
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| 1 |
EC50 = 7 nM
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| 2 |
EC50 = 12 nM
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| 3 |
IC50 = 153 nM
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| 4 |
Ki = 153 nM
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CP0487137
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(2S)-2-[[6-chloro-4-(2,6-dimethoxyphenyl)quinazoline-2-carbonyl]amino]-4-methylpentanoic acid
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|
C23H24ClN3O5
|
2
|
| 1 |
EC50 = 14 nM
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| 2 |
Ki = 88 nM
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CP0411578
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1-[[5-(2,6-dimethoxyphenyl)-1-naphthalen-1-ylpyrazole-3-carbonyl]amino]cyclohexane-1-carboxylic acid
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|
C29H29N3O5
|
2
|
| 1 |
EC50 = 18 nM
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|
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| 2 |
Ki = 116 nM
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CP0236745
|
CAS_184162-64-9
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|
C39H51N5O6
|
4
|
| 1 |
EC50 = 18 nM
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|
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| 2 |
EC50 = 20 nM
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| 3 |
Ki = 6 nM
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| 4 |
Ki = 7 nM
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CP0388570
|
1-[[5-(2,6-dimethoxyphenyl)-1-(4-fluorophenyl)pyrazole-3-carbonyl]amino]cyclohexane-1-carboxylic acid
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|
C25H26FN3O5
|
3
|
| 1 |
EC50 = 19 nM
|
|
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| 2 |
IC50 = 140 nM
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| 3 |
Ki = 140 nM
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CP0419097
|
1-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]cyclopentane-1-carboxylic acid
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|
C27H25ClN4O5
|
2
|
| 1 |
EC50 = 20 nM
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|
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| 2 |
Ki = 102 nM
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CP0419038
|
1-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]cycloheptane-1-carboxylic acid
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|
C29H29ClN4O5
|
2
|
| 1 |
EC50 = 21 nM
|
|
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| 2 |
Ki = 170 nM
|
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CP0440917
|
LEVOCABASTINE
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|
C26H29FN2O2
|
2
|
| 1 |
EC50 = 28 nM
|
|
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| 2 |
Ki = 33 nM
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CP0419100
|
1-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]cyclohexane-1-carboxylic acid
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|
C28H27ClN4O5
|
2
|
| 1 |
EC50 = 29 nM
|
|
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| 2 |
Ki = 151 nM
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CP0432228
|
1-[[5-(2,6-dimethoxyphenyl)-1-(4-fluorophenyl)pyrazol-3-yl]carbamoyl]cyclohexane-1-carboxylic acid
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|
C25H26FN3O5
|
2
|
| 1 |
EC50 = 55 nM
|
|
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| 2 |
Ki = 271 nM
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CP0447233
|
1-[[1-(7-chloroquinolin-4-yl)-5-(2-methoxyphenyl)pyrazole-3-carbonyl]amino]cyclohexane-1-carboxylic acid
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|
C27H25ClN4O4
|
2
|
| 1 |
EC50 = 62 nM
|
|
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| 2 |
Ki = 533 nM
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CP0419102
|
2-[[5-(2,6-dimethoxyphenyl)-1-(4-fluorophenyl)pyrazole-3-carbonyl]amino]adamantane-2-carboxylic acid
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|
C29H30FN3O5
|
2
|
| 1 |
EC50 = 68 nM
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|
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| 2 |
Ki = 110 nM
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CP0458456
|
(2S)-2-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)-4-ethylpyrazole-3-carbonyl]amino]-2-cyclohexylacetic acid
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|
C31H33ClN4O5
|
2
|
| 1 |
EC50 = 94 nM
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| 2 |
Ki = 1177 nM
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CP0489971
|
1-[[5-(2-methoxyphenyl)-1-naphthalen-1-ylpyrazole-3-carbonyl]amino]cyclohexane-1-carboxylic acid
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|
C28H27N3O4
|
2
|
| 1 |
EC50 = 108 nM
|
|
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| 2 |
Ki = 694 nM
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CP0137804
|
2-{[1-(7-Chloro-quinolin-4-yl)-5-(2,6-dimethoxy-phenyl)-1H-pyrazole-3-carbonyl]-amino}-adamantane-2-carboxylic acid
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|
C32H31ClN4O5
|
2
|
| 1 |
EC50 = 120 nM
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| 2 |
Ki = 62 nM
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CP0443418
|
1-[[6-chloro-4-(2,6-dimethoxyphenyl)quinazoline-2-carbonyl]amino]cyclohexane-1-carboxylic acid
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|
C24H24ClN3O5
|
2
|
| 1 |
EC50 = 145 nM
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|
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| 2 |
Ki = 959 nM
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CP0419099
|
(2S)-2-cyclohexyl-2-[[5-(2,6-dimethoxyphenyl)-1-naphthalen-1-ylpyrazole-3-carbonyl]amino]acetic acid
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|
C30H31N3O5
|
2
|
| 1 |
EC50 = 159 nM
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| 2 |
Ki = 536 nM
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CP0489975
|
(2S)-2-[[1-(7-chloroquinolin-4-yl)-5-(2,6-difluorophenyl)pyrazole-3-carbonyl]amino]-2-cyclohexylacetic acid
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|
C27H23ClF2N4O3
|
2
|
| 1 |
EC50 = 166 nM
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| 2 |
Ki = 1001 nM
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CP0546396
|
(2S)-2-[[1-(7-chloroquinolin-4-yl)-5-(2,5-dimethoxyphenyl)pyrazole-3-carbonyl]amino]-2-cyclohexylacetic acid
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|
C29H29ClN4O5
|
2
|
| 1 |
EC50 = 216 nM
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|
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| 2 |
Ki = 604 nM
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CP0378961
|
(2S)-2-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]-2-cyclohexylacetic acid
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|
C29H29ClN4O5
|
2
|
| 1 |
EC50 = 217 nM
|
|
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| 2 |
Ki = 644 nM
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CP0499520
|
(2S)-2-cyclohexyl-2-[[5-(2-methoxyphenyl)-1-naphthalen-1-ylpyrazole-3-carbonyl]amino]acetic acid
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|
C29H29N3O4
|
2
|
| 1 |
EC50 = 229 nM
|
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| 2 |
Ki = 2687 nM
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CP0440916
|
(2S)-2-[[1-(7-chloroquinolin-4-yl)-5-(2-methoxyphenyl)pyrazole-3-carbonyl]amino]-2-cyclohexylacetic acid
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|
C28H27ClN4O4
|
2
|
| 1 |
EC50 = 258 nM
|
|
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| 2 |
Ki = 1418 nM
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CP0440900
|
(2S)-2-cyclohexyl-2-[[5-(2,6-dimethoxyphenyl)-1-(4-fluorophenyl)pyrazole-3-carbonyl]amino]acetic acid
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|
C26H28FN3O5
|
2
|
| 1 |
EC50 = 271 nM
|
|
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| 2 |
Ki = 622 nM
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CP0440918
|
(2S)-2-[[1-(7-chloroquinolin-4-yl)-5-(2,4-dimethoxyphenyl)pyrazole-3-carbonyl]amino]-2-cyclohexylacetic acid
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|
C29H29ClN4O5
|
2
|
| 1 |
EC50 = 382 nM
|
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| 2 |
Ki = 1585 nM
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CP0398713
|
1-[[1-(4-fluorophenyl)-5-(2-methoxyphenyl)pyrazol-3-yl]carbamoyl]cyclohexane-1-carboxylic acid
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|
C24H24FN3O4
|
2
|
| 1 |
EC50 = 951 nM
|
|
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| 2 |
Ki = 6339 nM
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CP0483755
|
(2S)-2-[[6-chloro-4-(2,6-dimethoxyphenyl)quinazoline-2-carbonyl]amino]-2-cyclohexylacetic acid
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|
C25H26ClN3O5
|
3
|
| 1 |
EC50 > 10 nM
|
|
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| 2 |
IC50 = 1067 nM
|
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| 3 |
Ki = 474 nM
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CP0064604
|
(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-4-amino-2-[[(2S)-4-carboxy-2-[[(2S)-3-(4-hydroxyphenyl)-2-[[(2S)-4-methyl-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]amino]propanoyl]amino]butanoyl]amino]-4-oxobutanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid
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|
C78H121N21O20
|
5
|
| 1 |
EC50 > 100 nM
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|
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| 2 |
IC50 = 18.5 nM
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| 3 |
IC50 = 42 nM
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| 4 |
Ki = 18.9 nM
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| 5 |
Ki = 21 nM
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CP0150134
|
(S)-2-{(2S,3R)-2-[(S)-2-({(S)-1-[(S)-2-((S)-2-Amino-5-guanidino-pentanoylamino)-5-guanidino-pentanoyl]-pyrrolidine-2-carbonyl}-amino)-3-(4-hydroxy-phenyl)-propionylamino]-3-methyl-pentanoylamino}-4-methyl-pentanoic acid
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|
C38H64N12O8
|
2
|
| 1 |
IC50 = 5.4 nM
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| 2 |
Ki = 33 nM
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CP0419096
|
N-(2-adamantyl)-1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazole-3-carboxamide
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|
C31H31ClN4O3
|
1
|
| 1 |
Ki = 62 nM
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CP0386627
|
1-[[5-(2,6-dimethoxyphenyl)-1-naphthalen-1-ylpyrazol-3-yl]carbamoyl]cyclohexane-1-carboxylic acid
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|
C29H29N3O5
|
1
|
| 1 |
Ki = 128 nM
|
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CP0388569
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1-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazol-3-yl]carbamoyl]cyclohexane-1-carboxylic acid
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|
C28H27ClN4O5
|
1
|
| 1 |
Ki = 140 nM
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CP0418649
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(2S)-2-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazol-3-yl]methylamino]-2-cyclohexylacetic acid
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|
C29H31ClN4O4
|
1
|
| 1 |
Ki > 10000 nM
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