General Information of the Protein
Protein ID |
PT04331
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Protein Name |
Glutathione S-transferase omega-1
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Secondarily Protein Name |
Glutathione S-transferase omega 1-1
Glutathione-dependent dehydroascorbate reductase
Monomethylarsonic acid reductase
S-(Phenacyl)glutathione reductase
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Gene Name |
GSTO1
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Secondarily Gene Name |
GSTTLP28
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Sequence |
MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYGL
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Organism |
Homo sapiens, Human
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Protein Classification |
Enzyme
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Function |
Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid.
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Uniprot ID |
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Subcellular Location |
Cytoplasm
Cytosol
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Clinical Information about the Protein