General Information of the Protein
Protein ID
PT04331
Protein Name
Glutathione S-transferase omega-1
Secondarily
Protein Name
Glutathione S-transferase omega 1-1
Glutathione-dependent dehydroascorbate reductase
Monomethylarsonic acid reductase
S-(Phenacyl)glutathione reductase
Gene Name
GSTO1
Secondarily
Gene Name
GSTTLP28
Sequence
MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYGL
    Show/Hide
Organism
Homo sapiens, Human
Protein Classification
Enzyme
Function
Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid.
    Show/Hide
Uniprot ID
Primary ID:
P78417

Secondarily ID:
D3DRA3
F5H7H0
Q5TA03
Q7Z3T2
    Show/Hide
Ensembl ID
ENSG00000148834
HGNC ID
HGNC:13312
Subcellular Location
Cytoplasm
Cytosol
Clinical Information about the Protein
Target 1 ( Glutathione S-transferase omega-1 (GSTO-1) )
Target Type Preclinical Target
Disease 1 Target-related Disease  1
1 Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Preclinical Drug(s) 1 Preclinical Drug  1
1 Piperlongumine Preclinical
Solid tumour/cancer