General Information of the Protein
Protein ID
PT03245
Protein Name
Acetylcholine-binding protein
Sequence
MRRNIFCLACLWIVQACLSLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRSEIL
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Organism
Lymnaea stagnalis, Great pond snail, Helix stagnalis
Protein Classification
Unclassified protein
Function
Binds to acetylcholine. Modulates neuronal synaptic transmission.
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Uniprot ID
P58154
Subcellular Location
Synaptic cleft
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Compound ID Compound Name Compound Formula
CP0635625
 Compound Info 
3-methoxy-4-((2-(pyridin-3-yl)-5,6-dihydropyridin-3(4H)-ylidene)methyl)phenol
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C18H18N2O2
  1
1
Kd = 0.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0475362
 Compound Info 
3-(4-Aminobenzylidene)anabaseine
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C17H17N3
  1
1
Kd = 0.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0525007
 Compound Info 
3-(2,4-Dihydroxybenzylidene)anabaseine
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C17H16N2O2
  1
1
Kd = 0.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0009095
 Compound Info 
(3E)-3-[(2,4-DIMETHOXYPHENYL)METHYLIDENE]-3,4,5,6-TETRAHYDRO-2,3'-BIPYRIDINE
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C19H20N2O2
  1
1
Kd = 19 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Cell Line ID: CL000013 , Sf9
 Cell Line Info 
Biochemical Assays
Compound ID Compound Name Compound Formula
CP0000063
 Compound Info 
CAS_29790-52-1
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C10H14N2
  4
1 Ki = 63.1 nM
2 Ki = 100 nM
3 Ki = 316.23 nM
4 Ki = 496 nM
CP0000324
 Compound Info 
2-acetoxyethyl(trimethyl)ammonium;bromide
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C7H16NO2+
  1
1 Ki = 3162.28 nM