General Information of the Protein
| Protein ID |
PT02924
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| Protein Name |
Lysosomal protective protein
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| Secondarily Protein Name |
Carboxypeptidase C
Carboxypeptidase L
Cathepsin A
Protective protein cathepsin A
Protective protein for beta-galactosidase
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| Gene Name |
CTSA
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| Secondarily Gene Name |
PPGB
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| Sequence |
MIRAAPPPLFLLLLLLLLLVSWASRGEAAPDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDKVRMDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY
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| Organism |
Homo sapiens, Human
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| Protein Classification |
Enzyme
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Protease
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Serine protease
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Serine protease SC clan
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Serine protease S10 family
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| Function |
Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.
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| Uniprot ID |
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| Ensembl ID | |||||
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| Subcellular Location |
Lysosome
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Map of Molecular Bioactivity Related to the Protein
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Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000013 , Sf9
Clinical Information about the Protein
Target 1 ( Cathepsin A (CTSA) )
| Target Type | Clinical trial Target | ||||
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