General Information of the Protein
Protein ID
PT00809
Protein Name
Opioid receptor homologue
Gene Name
OPRD1A
Sequence
MEPSVIPGADIPDLYSINPFNVTFPDDVLSFVPDGRNYTEPNPVKSRGIIIAISITALYSVICVVGLLGNILVMYGVVRYTKLKTATNIYIFNLALADALATSTLPFQSTKYLMNTWPFGELLCKVVIAIDYYNMFTSIFTLTMMSVDRYIAVCHPVRALEFRTPIKAKIINVCIWILSSAVGVPIMIMAVTRVTNQNTTVCMLKFPDPDWYWDTVTKICVFIFAFVVPVLVITICYGLMILRLKSVRLLSGSKEKDRNMRRITRMVLVVVAAFIICWTPIHIFIIEKTLVDINQKNPFVIASWHLHRTGYTNSSLNPVLYAFLDENFKRCFRDFCLPFRTRADQSNLNRARNATREPVSVCALRIQERSRYD
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Organism
Danio rerio, Zebrafish, Brachydanio rerio
Protein Classification
Unclassified protein
Uniprot ID
O57585
Subcellular Location
Cell membrane,Multi-pass membrane protein
Membrane
Multi-pass membrane protein
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Compound ID Compound Name Compound Formula
CP0088373
 Compound Info 
(S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid
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C28H37N5O7
  1
1
Ki = 73 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0000305
 Compound Info 
(-)-(etorphine)
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C17H19NO3
  1
1
Ki = 223 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0393990
 Compound Info 
(2S,4S)-1-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypyrrolidine-2-carboxamide
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C36H50N6O12S
  1
1
Ki = 389.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0492753
 Compound Info 
(2S,4S)-1-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]-4-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypyrrolidine-2-carboxamide
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C36H50N6O12S
  1
1
Ki = 468.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0548554
 Compound Info 
(2S)-1-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carboxamide
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C30H40N6O6S
  1
1
Ki = 565.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0451640
 Compound Info 
(2S,4S)-1-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]-4-[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypyrrolidine-2-carboxamide
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C36H50N6O12S
  1
1
Ki = 608.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0413053
 Compound Info 
(2S,4S)-1-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]-4-[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2R,3S,4R,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxypyrrolidine-2-carboxamide
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C42H60N6O17S
  1
1
Ki = 634.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0447639
 Compound Info 
(2S,4S)-1-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]-4-[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxypyrrolidine-2-carboxamide
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C42H60N6O17S
  1
1
Ki = 843.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS