General Information of the Protein
Protein ID
PT00808
Protein Name
Mu-type opioid receptor
Gene Name
OR2
Sequence
MMENTGNISDLLYALSNPMVSNSSILCRNFSNSSGLVNMNSSVCDRTPELDKSSTPVIVAIIITALYSIVCVMGMGLVGNVLVMYVIIRYTKMKTATNIYIFNLALADSLATSTLPFQSVNYLMGTWPFGDELCKIVMSIDYYNMFTSIFTLTTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMVMASTTSDLHSNGIIDCTLLFPHPSWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIFVIIKALVTIPNSLLQTITWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCVPSPSVLDLQNSTRSRNPQRDGQSSGHTVDRTNQQV
    Show/Hide
Organism
Danio rerio, Zebrafish, Brachydanio rerio
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Opioid receptor
Uniprot ID
Q98UH1
Subcellular Location
Cell membrane
Multi-pass membrane protein
Cell projection axon? Cell projection dendrite?Membrane?pass membrane proteinaryon
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Compound ID Compound Name Compound Formula
CP0000305
 Compound Info 
(-)-(etorphine)
   Show/Hide
C17H19NO3
  2
1
Ki = 187 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki = 187.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0413053
 Compound Info 
(2S,4S)-1-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]-4-[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2R,3S,4R,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxypyrrolidine-2-carboxamide
   Show/Hide
C42H60N6O17S
  1
1
Ki = 202.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0447639
 Compound Info 
(2S,4S)-1-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]-4-[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxypyrrolidine-2-carboxamide
   Show/Hide
C42H60N6O17S
  1
1
Ki = 223.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0451640
 Compound Info 
(2S,4S)-1-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]-4-[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypyrrolidine-2-carboxamide
   Show/Hide
C36H50N6O12S
  1
1
Ki = 239.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0548554
 Compound Info 
(2S)-1-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carboxamide
   Show/Hide
C30H40N6O6S
  1
1
Ki = 269 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0393990
 Compound Info 
(2S,4S)-1-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypyrrolidine-2-carboxamide
   Show/Hide
C36H50N6O12S
  1
1
Ki = 312.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0492753
 Compound Info 
(2S,4S)-1-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-phenylpropanoyl]-4-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypyrrolidine-2-carboxamide
   Show/Hide
C36H50N6O12S
  1
1
Ki = 383.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0060012
 Compound Info 
(S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyric acid
   Show/Hide
C27H35N5O7S
  1
1
Ki = 684 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0088373
 Compound Info 
(S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid
   Show/Hide
C28H37N5O7
  1
1
Ki = 1317 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0486483
 Compound Info 
methyl (1R,5R,9R)-2-(2-phenylethyl)-2-azabicyclo[3.3.1]nonane-9-carboxylate;hydrochloride
   Show/Hide
C18H26ClNO2
  1
1
Ki = 8240 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0856963
 Compound Info 
2-(tert-butyl) 9-(3-hydroxyphenyl) (1R,5R,9R)-2-azabicyclo[3.3.1]nonane-2,9-dicarboxylate chlorhydrate salt
   Show/Hide
C15H20ClNO3
  1
1
Ki = 9520 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0893865
 Compound Info 
2-(tert-butyl) 9-(4-hydroxyphenyl) (1R,5R,9R)-2-azabicyclo[3.3.1]nonane-2,9-dicarboxylate chlorhydrate salt
   Show/Hide
C15H20ClNO3
  1
1
Ki = 12660 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0948470
 Compound Info 
2-(tert-butyl) 9-phenyl (1R,5R,9R)-2-azabicyclo[3.3.1]nonane-2,9-dicarboxylate chlorhydrate salt
   Show/Hide
C15H20ClNO2
  1
1
Ki = 32000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0947434
 Compound Info 
(1R,5R,9R)-9-(methoxycarbonyl)-2-azoniabicyclo[3.3.1]nonane chloride
   Show/Hide
C10H18ClNO2
  1
1
Ki = 35280 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0395968
 Compound Info 
methyl (1R,5R,9R)-2-benzyl-2-azabicyclo[3.3.1]nonane-9-carboxylate;hydrochloride
   Show/Hide
C17H24ClNO2
  1
1
Ki = 36980 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0477242
 Compound Info 
methyl (1R,5R,9R)-2-[(2S)-2-amino-3-phenylpropanoyl]-2-azabicyclo[3.3.1]nonane-9-carboxylate;hydrochloride
   Show/Hide
C19H27ClN2O3
  1
1
Ki = 75780 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0910701
 Compound Info 
(1R,5R,9R)-9-((S)-1-methoxy-1-oxo-3-phenylpropan-2-ylcarbamoyl)-2-azoniabicyclo[3.3.1]nonane chloride
   Show/Hide
C19H27ClN2O3
  1
1
Ki = 78020 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS