| Compound ID |
Compound Name |
Compound Formula |
|
CP0946120
|
5-(4-((2S,5S)-5-(4-Chlorobenzyl)-2-ethylmorpholino)-piperidin-1-yl)-4H-1,2,4-triazol-3-amine
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|
C20H29ClN6O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0839360
|
5-(4-((2S,5S)-5-(4-Chlorobenzyl)-2-isobutylmorpholino)-piperidin-1-yl)-4H-1,2,4-triazol-3-amine
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|
C22H33ClN6O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0719096
|
5-(4-((2S,5S)-5-(4-Chlorobenzyl)-2-isopropylmorpholino)-piperidin-1-yl)-4H-1,2,4-triazol-3-amine
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|
C21H31ClN6O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0946531
|
5-(4-((2R,5S)-5-(4-Chlorobenzyl)-2-(methoxymethyl)-morpholino)piperidin-1-yl)-4H-1,2,4-triazol-3-amine
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|
C20H29ClN6O2
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0957936
|
((2R,5S)-4-(1-(5-Amino-4H-1,2,4-triazol-3-yl)piperidin-4-yl)-5-(4-chlorobenzyl)morpholin-2-yl)methanol
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|
C19H27ClN6O2
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0719097
|
2-((2R,5S)-4-(1-(5-Amino-4H-1,2,4-triazol-3-yl)piperidin-4-yl)-5-(4-chlorobenzyl)morpholin-2-yl)propan-2-ol
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|
C21H31ClN6O2
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0719098
|
5-(4-((2S,5S)-5-(4-Chlorobenzyl)-2-methylmorpholino)-piperidin-1-yl)-4H-1,2,4-triazol-3-amine
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|
C19H27ClN6O
|
2
|
| 1 |
IC50 = 23 nM
|
|
|
| 2 |
Ki = 17.3 nM
|
|
|
|
CP0956391
|
(2R,5S)-4-(1-(5-Amino-4H-1,2,4-triazol-3-yl)piperidin-4-yl)-5-(4-chlorobenzyl)-N-methylmorpholine-2-carboxamide
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|
C20H28ClN7O2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0175801
|
3-[4-[(2R)-2-[(4-chlorophenyl)methyl]piperidin-1-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
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|
C19H27ClN6
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0230989
|
3-[4-[(3S)-3-[(4-chlorophenyl)methyl]morpholin-4-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
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|
C18H25ClN6O
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0323379
|
1-(5-amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(2-methylpropyl)piperidin-4-amine
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|
C19H29ClN6
|
1
|
| 1 |
IC50 = 232 nM
|
|
|
|
CP0686385
|
(S)-3-(4-(3-(4-chlorobenzyl)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)piperidin-1-yl)-1H-1,2,4-triazol-5-amine
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|
C23H27ClN6O
|
1
|
| 1 |
IC50 = 915 nM
|
|
|
|
CP0370214
|
3-[4-[(2S,5S)-2-[(4-chlorophenyl)methyl]-5-methyl-4-(2-methylpropyl)piperazin-1-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
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|
C23H36ClN7
|
1
|
| 1 |
IC50 = 1250 nM
|
|
|
|
CP0957172
|
(S)-4-(1-(5-Amino-4H-1,2,4-triazol-3-yl)piperidin-4-yl)-5-(4-chlorobenzyl)piperazin-2-one
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|
C18H24ClN7O
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0955868
|
(S)-4-(1-(5-Amino-4H-1,2,4-triazol-3-yl)piperidin-4-yl)-3-(4-chlorobenzyl)thiomorpholine-1,1-Dioxide
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|
C18H25ClN6O2S
|
1
|
| 1 |
IC50 = 4200 nM
|
|
|
|
CP0719095
|
5-(4-((2R,5S)-5-(4-Chlorobenzyl)-2-methylmorpholino)-piperidin-1-yl)-4H-1,2,4-triazol-3-amine
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|
C19H27ClN6O
|
1
|
| 1 |
IC50 = 5100 nM
|
|
|
|
CP0311092
|
3-[4-[(2S)-2-[(4-chlorophenyl)methyl]-4-methylpiperazin-1-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
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|
C19H28ClN7
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
