Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT04305 , Acid ceramidase
Gene Name ASAH1
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q13510
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT04305
 
Compound ID Compound Name Compound Formula
CP0564143
2-oxo-4-phenyl-N-(4- phenylbutyl)-1,3- benzoxazole-3-carboxamide
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C24H22N2O3
 1
1
IC50 = 0.8 nM
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CP0519523
2-amino-N-(4-phenylbutyl)benzimidazole-1-carboxamide
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C18H20N4O
 1
1
IC50 = 0.9 nM
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CP0416935
2-methyl-N-(4-phenylbutyl)benzimidazole-1-carboxamide
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C19H21N3O
 1
1
IC50 = 1 nM
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CP0532566
N-(4-phenylbutyl)triazolo[4,5-b]pyridine-1-carboxamide
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C16H17N5O
 1
1
IC50 = 1.3 nM
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CP0539212
N-(4-phenylbutyl)benzotriazole-1-carboxamide
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C17H18N4O
 1
1
IC50 = 2.1 nM
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CP0574468
N-hexyltriazolo[4,5-b]pyridine-1-carboxamide
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C12H17N5O
 1
1
IC50 = 2.2 nM
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CP0519525
1,3-dioxo-N-(4-phenylbutyl)isoindole-2-carboxamide
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C19H18N2O3
 1
1
IC50 = 2.4 nM
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CP0546297
2-amino-N-hexylbenzimidazole-1-carboxamide
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C14H20N4O
 1
1
IC50 = 2.4 nM
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CP0357130
N-(4-phenylbutyl)benzimidazole-1-carboxamide
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C18H19N3O
 1
1
IC50 = 2.5 nM
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CP0385258
6-nitro-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-3-carboxamide
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C18H17N3O5
 1
1
IC50 = 3 nM
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CP0472573
5-nitro-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-3-carboxamide
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C18H17N3O5
 1
1
IC50 = 3 nM
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CP0541653
2-oxo-N-(4-phenylbutyl)-[1,3]oxazolo[5,4-c]pyridine-1-carboxamide
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C17H17N3O3
 1
1
IC50 = 3 nM
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CP0416933
N-hexylbenzotriazole-1-carboxamide
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C13H18N4O
 1
1
IC50 = 4.1 nM
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CP0546298
N-(4-phenylbutyl)indazole-1-carboxamide
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C18H19N3O
 1
1
IC50 = 4.7 nM
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CP0390639
2-oxo-N-(4-phenylbutyl)-[1,3]oxazolo[4,5-c]pyridine-3-carboxamide
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C17H17N3O3
 1
1
IC50 = 6 nM
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CP0148179
Benzoimidazole-1-Carboxylic Acid Hexylamide
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C14H19N3O
 1
1
IC50 = 6.6 nM
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CP0539213
N-hexyl-1,3-dioxoisoindole-2-carboxamide
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C15H18N2O3
 1
1
IC50 = 7 nM
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CP0566107
2-amino-N-[(4-methylphenyl)methyl]benzimidazole-1-carboxamide
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C16H16N4O
 1
1
IC50 = 7 nM
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CP0416937
N-[(3-methylphenyl)methyl]benzimidazole-1-carboxamide
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C16H15N3O
 1
1
IC50 = 8.3 nM
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CP0546299
2-amino-N-[(3-methylphenyl)methyl]benzimidazole-1-carboxamide
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C16H16N4O
 1
1
IC50 = 8.5 nM
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CP0519524
N-hexylindazole-1-carboxamide
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C14H19N3O
 1
1
IC50 = 9.9 nM
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CP0420657
5-fluoro-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-3-carboxamide
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C18H17FN2O3
 1
1
IC50 = 12 nM
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CP0416938
2-methoxy-N-(4-phenylbutyl)benzimidazole-1-carboxamide
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C19H21N3O2
 1
1
IC50 = 13.9 nM
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CP0403503
6-(4-chlorobenzoyl)-2-oxo-N- (4-phenylbutyl)-1,3- benzoxazole-3-carboxamide
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C25H21ClN2O4
 1
1
IC50 = 14 nM
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CP0416939
N-[(4-methylphenyl)methyl]benzimidazole-1-carboxamide
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C16H15N3O
 1
1
IC50 = 14.8 nM
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CP0538435
5-chloro-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-3-carboxamide
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C18H17ClN2O3
 1
1
IC50 = 15 nM
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CP0472112
5,6-dichloro-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-3-carboxamide
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C18H16Cl2N2O3
 1
1
IC50 = 18 nM
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CP0472574
7-bromo-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-3-carboxamide
   Show/Hide
C18H17BrN2O3
 1
1
IC50 = 18 nM
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CP0538125
2-oxo-N-(4-phenylbutyl)-5- (trifluoromethyl)-1,3- benzoxazole-3-carboxamide
   Show/Hide
C19H17F3N2O3
 1
1
IC50 = 18 nM
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CP0429842
2-oxo-N-[(4- propylphenyl)methyl]-1,3- benzoxazole-3-carboxamide
   Show/Hide
C18H18N2O3
 1
1
IC50 = 19 nM
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CP0417300
2-oxo-N-(4-phenylbutyl)-6- (trifluoromethyl)-1,3- benzoxazole-3-carboxamide
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C19H17F3N2O3
 1
1
IC50 = 20 nM
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CP0043665
CARMOFUR
   Show/Hide
C11H16FN3O3
 1
1
IC50 = 20.7 nM
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CP0416934
2-oxo-1-N,3-N-bis(4-phenylbutyl)benzimidazole-1,3-dicarboxamide
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C29H32N4O3
 1
1
IC50 = 21 nM
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CP0538436
5-bromo-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-3-carboxamide
   Show/Hide
C18H17BrN2O3
 1
1
IC50 = 22 nM
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CP0534764
N-benzylbenzimidazole-1-carboxamide
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C15H13N3O
 1
1
IC50 = 22.5 nM
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CP0406976
7-methyl-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-3-carboxamide
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C19H20N2O3
 1
1
IC50 = 23 nM
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CP0468114
5-benzoyl-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamide
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C25H22N2O4
 1
1
IC50 = 24 nM
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CP0435614
5-fluoro-6-(1-methylpiperidin-4-yl)-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamide
   Show/Hide
C24H28FN3O3
 1
1
IC50 = 24 nM
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CP0564145
2-oxo-N-[4-(p-tolyl)butyl]- 1,3-benzoxazole-3- carboxamide
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C19H20N2O3
 1
1
IC50 = 25 nM
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CP0459975
6-benzoyl-2-oxo-N-(4-phenyl- butyl)-1,3-benzoxazole-3- carboxamide
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C25H22N2O4
 1
1
IC50 = 29 nM
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CP0393509
2-amino-N-benzylbenzimidazole-1-carboxamide
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C15H14N4O
 1
1
IC50 = 29.3 nM
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CP0406913
6-bromo-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-3-carboxamide
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C18H17BrN2O3
 1
1
IC50 = 31 nM
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CP0564144
6-fluoro-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-3-carboxamide
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C18H17FN2O3
 1
1
IC50 = 31 nM
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CP0380164
6-chloro-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-3-carboxamide
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C18H17ClN2O3
 1
1
IC50 = 33 nM
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CP0564146
2-oxo-N-[4-(2-thienyl)butyl]- 1,3-benzoxazole-3- carboxamide
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C16H16N2O3S
 1
1
IC50 = 37 nM
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CP0459971
2-oxo-5-phenyl-N-(4- phenylbutyl)-1,3- benzoxazole-3-carboxamide
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C24H22N2O3
 1
1
IC50 = 42 nM
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CP0538439
2-oxo-N-(6-phenylhexyl)-1,3- benzoxazole-3-carboxamide
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C20H22N2O3
 1
1
IC50 = 51 nM
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CP0435613
6-(4-methyl-2-oxopiperazin-1-yl)-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamide
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C23H26N4O4
 1
1
IC50 = 52 nM
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CP0385259
2-oxo-N-(5-phenylpentyl)- 1,3-benzoxazole-3- carboxamide
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C19H20N2O3
 1
1
IC50 = 54 nM
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CP0538438
2-oxo-N-(3-phenylpropyl)- 1,3-benzoxazole-3- carboxamide
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C17H16N2O3
 1
1
IC50 = 55 nM
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CP0546300
N-[(2-methylphenyl)methyl]benzimidazole-1-carboxamide
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C16H15N3O
 1
1
IC50 = 55.9 nM
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CP0406914
5-(4-fluorophenyl)-2-oxo-N- (4-phenylbutyl)-1,3- benzoxazole-3-carboxamide
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C24H21FN2O3
 1
1
IC50 = 56 nM
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CP0553250
6-(4-ethylpiperazin-1-yl)-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamide
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C24H30N4O3
 1
1
IC50 = 56 nM
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CP0534948
6-(4-fluorophenyl)-2-oxo-N-pentyl-1,3-benzoxazole-3-carboxamide
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C19H19FN2O3
 1
1
IC50 = 60 nM
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CP0538444
N-[4-(4- methoxyphenyl)butyl]-2-oxo- 1,3-benzoxazole-3- carboxamide
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C19H20N2O4
 1
1
IC50 = 63 nM
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CP0238138
2-oxo-N-(4-phenylbutyl)-1,3- benzoxazole-3-carboxamide
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C18H18N2O3
 1
1
IC50 = 64 nM
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CP0482252
6-(1-acetylpiperidin-4-yl)-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamide
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C25H29N3O4
 1
1
IC50 = 64 nM
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CP0385260
N-(2-benzylsulfanylethyl)-2-oxo-1,3-benzoxazole-3-carboxamide
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C17H16N2O3S
 1
1
IC50 = 65 nM
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CP0420660
6-methyl-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-3-carboxamide
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C19H20N2O3
 1
1
IC50 = 66 nM
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CP0406978
5-(4-methoxyphenyl)-2-oxo- N-(4-phenylbutyl)-1,3- benzoxazole-3-carboxamide
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C25H24N2O4
 1
1
IC50 = 67 nM
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CP0459972
6-(4-methoxyphenyl)-2-oxo- N-(4-phenylbutyl)-1,3- benzoxazole-3-carboxamide
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C25H24N2O4
 1
1
IC50 = 67 nM
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CP0558812
6-(oxan-4-yl)-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamide
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C23H26N2O4
 1
1
IC50 = 68 nM
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CP0416936
2-amino-N-[(2-methylphenyl)methyl]benzimidazole-1-carboxamide
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C16H16N4O
 1
1
IC50 = 68.4 nM
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CP0472114
N-[4-(2-naphthyl)butyl]-2- oxo-1,3-benzoxazole-3- carboxamide
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C22H20N2O3
 1
1
IC50 = 71 nM
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CP0406915
N-[4-(4-fluorophenyl)butyl]- 2-oxo-1,3-benzoxazole-3- carboxamide
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C18H17FN2O3
 1
1
IC50 = 75 nM
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CP0397739
6-(4-fluorophenyl)-2-oxo-N- (4-phenylbutyl)-1,3- benzoxazole-3-carboxamide
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C24H21FN2O3
 1
1
IC50 = 79 nM
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CP0537135
2-oxo-N-(4-phenylbutyl)-6-piperidin-1-yl-1,3-benzoxazole-3-carboxamide;hydrochloride
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C23H28ClN3O3
 1
1
IC50 = 80 nM
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CP0406977
2-oxo-6-phenyl-N-(4- phenylbutyl)-1,3- benzoxazole-3-carboxamide
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C24H22N2O3
 1
1
IC50 = 84 nM
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CP0520104
6-cyclohexyl-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamide
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C24H28N2O3
 1
1
IC50 = 89 nM
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CP0538437
2-oxo-7-phenyl-N-(4- phenylbutyl)-1,3- benzoxazole-3-carboxamide
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C24H22N2O3
 1
1
IC50 = 91 nM
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CP0427308
6-(1-ethylpiperidin-4-yl)-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamide
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C25H31N3O3
 1
1
IC50 = 92 nM
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CP0534947
6-(4-methyl-3-oxopiperazin-1-yl)-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamide
   Show/Hide
C23H26N4O4
 1
1
IC50 = 92 nM
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CP0533366
2-oxo-N-(4-phenylbutyl)-6-(1-propan-2-ylpiperidin-4-yl)-1,3-benzoxazole-3-carboxamide
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C26H33N3O3
 1
1
IC50 = 94 nM
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CP0575431
N-[4-(4-fluorophenyl)butyl]-6-(1-methylpiperidin-4-yl)-2-oxo-1,3-benzoxazole-3-carboxamide
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C24H28FN3O3
 1
1
IC50 = 94 nM
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CP0550697
6-[1-(2,2-difluoroethyl)piperidin-4-yl]-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamide
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C25H29F2N3O3
 1
1
IC50 = 95 nM
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CP0519159
6-(1-methyl-2-oxopiperidin-4-yl)-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamide
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C24H27N3O4
 1
1
IC50 = 105 nM
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CP0553251
6-(4-methylpiperazin-1-yl)-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamide
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C23H28N4O3
 1
1
IC50 = 116 nM
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CP0403502
5-methyl-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-3-carboxamide
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C19H20N2O3
 1
1
IC50 = 117 nM
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CP0550695
6-[1-(2-methylpropyl)piperidin-4-yl]-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamide
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C27H35N3O3
 1
1
IC50 = 120 nM
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CP0472113
2-oxo-N-(2-phenylethyl)-1,3-benzoxazole-3-carboxamide
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C16H14N2O3
 1
1
IC50 = 121 nM
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CP0435612
6-[4-(2-methylpropyl)piperazin-1-yl]-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamide
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C26H34N4O3
 1
1
IC50 = 127 nM
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CP0537136
6-(1-methylpiperidin-4-yl)-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamide
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C24H29N3O3
 1
1
IC50 = 129 nM
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CP0550696
2-oxo-N-(4-phenylbutyl)-6-piperidin-4-yl-1,3-benzoxazole-3-carboxamide;hydrochloride
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C23H28ClN3O3
 1
1
IC50 = 134 nM
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CP0553252
6-(1,1-dioxo-1,4-thiazinan-4-yl)-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamide
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C22H25N3O5S
 1
1
IC50 = 160 nM
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CP0237970
6-(1-methylpiperidin-4-yl)-N-(2-methylpropyl)-2-oxo-1,3-benzoxazole-3-carboxamide
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C18H25N3O3
 1
1
IC50 = 166 nM
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CP0537134
6-morpholin-4-yl-2-oxo-N-(4-phenylbutyl)-1,3-benzoxazole-3-carboxamide
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C22H25N3O4
 1
1
IC50 = 192 nM
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CP0390638
2-oxo-N-(4-phenylbutyl)-6-(4-propan-2-ylpiperazin-1-yl)-1,3-benzoxazole-3-carboxamide
   Show/Hide
C25H32N4O3
 1
1
IC50 = 211 nM
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CP0567516
6-(1-methylpiperidin-4-yl)-2-oxo-N-(2-phenylmethoxyethyl)-1,3-benzoxazole-3-carboxamide
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C23H27N3O4
 1
1
IC50 = 215 nM
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CP0519162
2-oxo-N-(4-phenylbutyl)-4,5,6,7-tetrahydro-[1,3]oxazolo[4,5-c]pyridine-3-carboxamide
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C17H21N3O3
 1
1
IC50 = 247 nM
   TI
   LI
   LO
   TS
CP0570963
5-acetyl-2-oxo-N-(4-phenylbutyl)-6,7-dihydro-4H-[1,3]oxazolo[4,5-c]pyridine-3-carboxamide
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C19H23N3O4
 1
1
IC50 = 293 nM
   TI
   LI
   LO
   TS
CP0435615
5-(1-methylpiperidin-4-yl)-N-(2-methylpropyl)-2-oxo-1,3-benzoxazole-3-carboxamide
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C18H25N3O3
 1
1
IC50 = 295 nM
   TI
   LI
   LO
   TS
CP0457682
4-cyclohexylbutyl N-[(2S,3S)-2-methyl-4-oxo-1-phenoxyazetidin-3-yl]carbamate
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C21H30N2O4
 1
1
IC50 = 300 nM
   TI
   LI
   LO
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CP0538440
N-[4-(4-nitrophenyl)butyl]-2-oxo-1,3-benzoxazole-3-carboxamide
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C18H17N3O5
 1
1
IC50 = 312 nM
   TI
   LI
   LO
   TS
CP0537927
2-oxo-N-(4-phenylbutyl)-4,5,6,7-tetrahydro-[1,3]oxazolo[5,4-c]pyridine-1-carboxamide
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C17H21N3O3
 1
1
IC50 = 340 nM
   TI
   LI
   LO
   TS
CP0520103
2-oxo-N-(4-phenylbutyl)-6-piperazin-1-yl-1,3-benzoxazole-3-carboxamide;hydrochloride
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C22H27ClN4O3
 1
1
IC50 = 363 nM
   TI
   LI
   LO
   TS
CP0575430
6-(1-methylpiperidin-4-yl)-2-oxo-N-pentyl-1,3-benzoxazole-3-carboxamide
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C19H27N3O3
 1
1
IC50 = 396 nM
   TI
   LI
   LO
   TS
CP0550698
5-benzyl-2-oxo-N-(4-phenylbutyl)-6,7-dihydro-4H-[1,3]oxazolo[4,5-c]pyridine-3-carboxamide
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C24H27N3O3
 1
1
IC50 = 436 nM
   TI
   LI
   LO
   TS
CP0533367
5-methyl-2-oxo-N-(4-phenylbutyl)-6,7-dihydro-4H-[1,3]oxazolo[4,5-c]pyridine-3-carboxamide
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C18H23N3O3
 1
1
IC50 = 516 nM
   TI
   LI
   LO
   TS
CP0557897
7-(1-methylpiperidin-4-yl)-N-(2-methylpropyl)-2-oxo-1,3-benzoxazole-3-carboxamide
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C18H25N3O3
 1
1
IC50 = 535 nM
   TI
   LI
   LO
   TS
CP0472115
2-oxo-N-(2-phenylmethoxyethyl)-1,3-benzoxazole-3-carboxamide
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C17H16N2O4
 1
1
IC50 = 649 nM
   TI
   LI
   LO
   TS
CP0557899
6-(1-methylpiperidin-2-yl)-N-(2-methylpropyl)-2-oxo-1,3-benzoxazole-3-carboxamide
   Show/Hide
C18H25N3O3
 1
1
IC50 = 1010 nM
   TI
   LI
   LO
   TS
CP0520125
N-(2-ethoxyethyl)-6-(1-methylpiperidin-4-yl)-2-oxo-1,3-benzoxazole-3-carboxamide
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C18H25N3O4
 1
1
IC50 = 1049 nM
   TI
   LI
   LO
   TS
CP0570962
6-(1-methylpiperidin-3-yl)-N-(2-methylpropyl)-2-oxo-1,3-benzoxazole-3-carboxamide
   Show/Hide
C18H25N3O3
 1
1
IC50 = 1750 nM
   TI
   LI
   LO
   TS
CP0410125
4-cyclohexylbutyl N-[(2S,3S)-2-methyl-1-(4-methylsulfonylphenoxy)-4-oxoazetidin-3-yl]carbamate
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C22H32N2O6S
 1
1
IC50 = 2020 nM
   TI
   LI
   LO
   TS
CP0542249
N-butan-2-yl-6-(1-methylpiperidin-4-yl)-2-oxo-1,3-benzoxazole-3-carboxamide
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C18H25N3O3
 1
1
IC50 = 2095 nM
   TI
   LI
   LO
   TS
CP0482253
N-(2-ethoxyethyl)-6-(4-fluorophenyl)-2-oxo-1,3-benzoxazole-3-carboxamide
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C18H17FN2O4
 1
1
IC50 = 2300 nM
   TI
   LI
   LO
   TS
CP0537926
6-(4-fluorophenyl)-N-(3-methoxypropyl)-2-oxo-1,3-benzoxazole-3-carboxamide
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C18H17FN2O4
 1
1
IC50 = 2600 nM
   TI
   LI
   LO
   TS
CP0567517
6-(4-fluorophenyl)-2-oxo-N-(2-phenylmethoxyethyl)-1,3-benzoxazole-3-carboxamide
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C23H19FN2O4
 1
1
IC50 = 4700 nM
   TI
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   LO
   TS
CP0532561
1-(1,3-benzoxazol-2-yl)-3-hexylurea
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C14H19N3O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0534762
1-(1,3-benzothiazol-2-yl)-3-hexylurea
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C14H19N3OS
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0534763
1-(1,3-benzoxazol-2-yl)-3-(4-phenylbutyl)urea
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C18H19N3O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0543174
1-(1H-benzimidazol-2-yl)-3-(4-phenylbutyl)urea
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C18H20N4O
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0548824
1-(1,3-benzothiazol-2-yl)-3-(4-phenylbutyl)urea
   Show/Hide
C18H19N3OS
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0558678
2-oxo-N-(4-phenylbutyl)-3H-benzimidazole-1-carboxamide
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C18H19N3O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0574467
1-(1H-benzimidazol-2-yl)-3-hexylurea
   Show/Hide
C14H20N4O
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS