Brief Information of the Cell Line and Protein
Cell Line ID: CL000103 , LS174T
 Cell Line Info 
Synonyms
Ls174T
LS174t
Ls-174-T
LS-174-T
LS 174 T
LS-174T
Ls-174T
LS 174T
LS-174
LS174
Laboratory of Surgery 174T
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1384
Protein ID: PT04100 , Neurogenic locus notch homolog protein 1
 Protein Info 
Gene Name NOTCH1
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P46531
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000103
 Cell Line Info 
 Protein ID: PT04100
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0014683
 Compound Info 
Asclepin
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C31H42O10
  1
1
IC50 = 300 nM
 Bioactivity Info 
   TI
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   LO
   TS
CP0483146
 Compound Info 
(1'S,2S,3'R,5'S,7'R,10'R,12'R,14'R,15'S,18'R,19'R,22'S,23'R)-10',22'-dihydroxy-7',18'-dimethyl-4-oxo-19'-(5-oxo-2H-furan-3-yl)spiro[1,3-thiazolidine-2,9'-4,6,11-trioxahexacyclo[12.11.0.03,12.05,10.015,23.018,22]pentacosane]-14'-carbaldehyde
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C31H41NO9S
  1
1
IC50 = 300 nM
 Bioactivity Info 
   TI
   LI
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CP0008391
 Compound Info 
Uscharin
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C31H41NO8S
  1
1
IC50 = 400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0483145
 Compound Info 
(1S,3R,5S,7R,9S,10R,12R,14R,15S,18R,19R,20R,22S,23R)-10,20,22-trihydroxy-7,18-dimethyl-19-(5-oxo-2H-furan-3-yl)spiro[4,6,11-trioxahexacyclo[12.11.0.03,12.05,10.015,23.018,22]pentacosane-9,2'-5H-1,3-thiazole]-14-carbaldehyde
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C31H41NO9S
  1
1
IC50 = 700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0012114
 Compound Info 
CHEBI:3329
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C29H40O9
  1
1
IC50 = 800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0486163
 Compound Info 
(1'S,2S,3'R,5'S,7'R,10'R,12'R,14'R,15'S,18'R,19'R,22'S,23'R)-10',22'-dihydroxy-7',18'-dimethyl-19'-(5-oxo-2H-furan-3-yl)spiro[1,3-thiazolidine-2,9'-4,6,11-trioxahexacyclo[12.11.0.03,12.05,10.015,23.018,22]pentacosane]-14'-carbaldehyde
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C31H43NO8S
  1
1
IC50 = 2000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0412500
 Compound Info 
CHEBI:9913
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C29H38O9
  1
1
IC50 = 2400 nM
 Bioactivity Info 
   TI
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CP0545579
 Compound Info 
methyl (2S,3R,5R)-2-[[(2R,3R,5S,8R,9S,10R,13R,14S,16R,17R)-10-formyl-2,14,16-trihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]oxy]-3-hydroxy-5-methyloxolane-3-carboxylate
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C30H42O11
  1
1
IC50 = 17300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS