| Compound ID |
Compound Name |
Compound Formula |
|
CP0555573
|
N-[3-[2-(3,3-difluoropiperidin-1-yl)-2-oxoethyl]-6-[3-(dimethylamino)phenoxy]-4-oxoquinazolin-7-yl]-2-[[4-(trifluoromethyl)phenyl]methoxy]acetamide
Show/Hide
|
C33H32F5N5O5
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0507496
|
N-[6-[3-(dimethylamino)phenoxy]-3-[2-(4-fluoropiperidin-1-yl)-2-oxoethyl]-4-oxoquinazolin-7-yl]-2-[[4-(trifluoromethyl)phenyl]methoxy]acetamide
Show/Hide
|
C33H33F4N5O5
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0531220
|
[3-[(3-butyl-1,2,4-oxadiazol-5-yl)methyl]-7-methyl-1,1-dioxo-3H-1,2-benzothiazol-2-yl]-[3-(trifluoromethyl)phenyl]methanone
Show/Hide
|
C23H22F3N3O4S
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0549360
|
N-[6-[3-(dimethylamino)phenoxy]-4-oxo-3-(2-oxo-2-piperidin-1-ylethyl)quinazolin-7-yl]-2-[[4-(trifluoromethyl)phenyl]methoxy]acetamide
Show/Hide
|
C33H34F3N5O5
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0569503
|
N-[3-[2-(4,4-difluoropiperidin-1-yl)-2-oxoethyl]-6-[3-(dimethylamino)phenoxy]-4-oxoquinazolin-7-yl]-2-[[4-(trifluoromethyl)phenyl]methoxy]acetamide
Show/Hide
|
C33H32F5N5O5
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0450896
|
N-[3-[2-(3,3-difluoropiperidin-1-yl)-2-oxoethyl]-6-(3-morpholin-4-ylphenoxy)-4-oxoquinazolin-7-yl]-2-[[4-(trifluoromethyl)phenyl]methoxy]acetamide
Show/Hide
|
C35H34F5N5O6
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
|
CP0546025
|
methyl 2-[6-(3-morpholin-4-ylphenoxy)-4-oxo-7-[[2-[[4-(trifluoromethyl)phenyl]methoxy]acetyl]amino]quinazolin-3-yl]acetate
Show/Hide
|
C31H29F3N4O7
|
1
|
| 1 |
IC50 = 650 nM
|
|
|
|
CP0570859
|
6-(3-chlorophenyl)-4-oxo-3-(2-oxo-2-piperidin-1-ylethyl)-N-[3-[4-(trifluoromethyl)phenoxy]propyl]quinazoline-7-carboxamide
Show/Hide
|
C32H30ClF3N4O4
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0450905
|
6-(3-chlorophenyl)-4-oxo-N-[3-[4-(trifluoromethyl)phenoxy]propyl]-3H-quinazoline-7-carboxamide
Show/Hide
|
C25H19ClF3N3O3
|
1
|
| 1 |
IC50 = 840 nM
|
|
|
|
CP0450894
|
methyl 2-[6-(3-chlorophenyl)-4-oxo-7-[3-[4-(trifluoromethyl)phenoxy]propylcarbamoyl]quinazolin-3-yl]acetate
Show/Hide
|
C28H23ClF3N3O5
|
1
|
| 1 |
IC50 = 890 nM
|
|
|
|
CP0484382
|
butyl 2-[7-methyl-1,1-dioxo-2-[3-(trifluoromethyl)benzoyl]-3H-1,2-benzothiazol-3-yl]acetate
Show/Hide
|
C22H22F3NO5S
|
1
|
| 1 |
IC50 = 1050 nM
|
|
|
|
CP0490963
|
butyl 2-[7-methyl-1,1-dioxo-2-[2-(trifluoromethyl)benzoyl]-3H-1,2-benzothiazol-3-yl]acetate
Show/Hide
|
C22H22F3NO5S
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0450893
|
methyl 2-[6-(3-chlorophenyl)-4-oxo-7-[2-[[4-(trifluoromethyl)phenyl]methoxy]ethylcarbamoyl]quinazolin-3-yl]acetate
Show/Hide
|
C28H23ClF3N3O5
|
1
|
| 1 |
IC50 = 1120 nM
|
|
|
|
CP0450895
|
6-(3-chlorophenyl)-3-[2-(3,3-difluoropiperidin-1-yl)-2-oxoethyl]-4-oxo-N-[3-[4-(trifluoromethyl)phenoxy]propyl]quinazoline-7-carboxamide
Show/Hide
|
C32H28ClF5N4O4
|
1
|
| 1 |
IC50 = 1130 nM
|
|
|
|
CP0557868
|
methyl 2-[6-[3-(dimethylamino)phenoxy]-4-oxo-7-[[2-[[4-(trifluoromethyl)phenyl]methoxy]acetyl]amino]quinazolin-3-yl]acetate
Show/Hide
|
C29H27F3N4O6
|
1
|
| 1 |
IC50 = 1150 nM
|
|
|
|
CP0490960
|
butyl 2-[7-methyl-1,1-dioxo-2-[4-(trifluoromethyl)benzoyl]-3H-1,2-benzothiazol-3-yl]acetate
Show/Hide
|
C22H22F3NO5S
|
1
|
| 1 |
IC50 = 1310 nM
|
|
|
|
CP0466195
|
6-(3-chlorophenyl)-4-oxo-N-[2-[[4-(trifluoromethyl)phenyl]methoxy]ethyl]-3H-quinazoline-7-carboxamide
Show/Hide
|
C25H19ClF3N3O3
|
1
|
| 1 |
IC50 = 1340 nM
|
|
|
|
CP0444046
|
methyl 2-[6-(3-morpholin-4-ylphenoxy)-4-oxo-7-[4-[4-(trifluoromethyl)phenoxy]butanoylamino]quinazolin-3-yl]acetate
Show/Hide
|
C32H31F3N4O7
|
1
|
| 1 |
IC50 = 1380 nM
|
|
|
|
CP0487871
|
butyl 2-[7-chloro-1,1-dioxo-2-[4-(trifluoromethyl)benzoyl]-3H-1,2-benzothiazol-3-yl]acetate
Show/Hide
|
C21H19ClF3NO5S
|
1
|
| 1 |
IC50 = 1630 nM
|
|
|
|
CP0573079
|
methyl 2-[6-(3-chlorophenyl)-7-[3-(4-chlorophenyl)propylcarbamoyl]-4-oxoquinazolin-3-yl]acetate
Show/Hide
|
C27H23Cl2N3O4
|
1
|
| 1 |
IC50 = 1640 nM
|
|
|
|
CP0555349
|
methyl 2-[6-[2-(dimethylamino)phenoxy]-4-oxo-7-[[2-[[4-(trifluoromethyl)phenyl]methoxy]acetyl]amino]quinazolin-3-yl]acetate
Show/Hide
|
C29H27F3N4O6
|
1
|
| 1 |
IC50 = 1650 nM
|
|
|
|
CP0487872
|
[3-[(5-butyl-1,3,4-oxadiazol-2-yl)methyl]-7-methyl-1,1-dioxo-3H-1,2-benzothiazol-2-yl]-[3-(trifluoromethyl)phenyl]methanone
Show/Hide
|
C23H22F3N3O4S
|
1
|
| 1 |
IC50 = 1740 nM
|
|
|
|
CP0418677
|
butyl 2-[2-(4-chlorobenzoyl)-7-methyl-1,1-dioxo-3H-1,2-benzothiazol-3-yl]acetate
Show/Hide
|
C21H22ClNO5S
|
1
|
| 1 |
IC50 = 2140 nM
|
|
|
|
CP0563956
|
butyl 2-[5,7-dimethyl-1,1-dioxo-2-[4-(trifluoromethyl)benzoyl]-3H-1,2-benzothiazol-3-yl]acetate
Show/Hide
|
C23H24F3NO5S
|
1
|
| 1 |
IC50 = 2460 nM
|
|
|
|
CP0552235
|
3-(2-butoxyethyl)-7-methyl-2-[4-(trifluoromethyl)benzoyl]-3H-isoindol-1-one
Show/Hide
|
C23H24F3NO3
|
1
|
| 1 |
IC50 = 2470 nM
|
|
|
|
CP0557801
|
N-[6-(3-morpholin-4-ylphenoxy)-4-oxo-3H-quinazolin-7-yl]-4-[4-(trifluoromethyl)phenoxy]butanamide
Show/Hide
|
C29H27F3N4O5
|
1
|
| 1 |
IC50 = 2480 nM
|
|
|
|
CP0552891
|
methyl 2-[6-[3-(dimethylamino)phenoxy]-4-oxo-7-[4-[4-(trifluoromethyl)phenoxy]butanoylamino]quinazolin-3-yl]acetate
Show/Hide
|
C30H29F3N4O6
|
1
|
| 1 |
IC50 = 2650 nM
|
|
|
|
CP0532034
|
butyl 3-(2-butoxy-2-oxoethyl)-1,1-dioxo-2-[4-(trifluoromethyl)benzoyl]-3H-1,2-benzothiazole-7-carboxylate
Show/Hide
|
C26H28F3NO7S
|
1
|
| 1 |
IC50 = 2930 nM
|
|
|
|
CP0423077
|
methyl 2-[7-methyl-1,1-dioxo-2-[4-(trifluoromethyl)benzoyl]-3H-1,2-benzothiazol-3-yl]acetate
Show/Hide
|
C19H16F3NO5S
|
1
|
| 1 |
IC50 = 2980 nM
|
|
|
|
CP0532033
|
butyl 2-[5,7-dimethoxy-1,1-dioxo-2-[4-(trifluoromethyl)benzoyl]-3H-1,2-benzothiazol-3-yl]acetate
Show/Hide
|
C23H24F3NO7S
|
1
|
| 1 |
IC50 = 3150 nM
|
|
|
|
CP0570928
|
methyl 2-[7-[3-(4-chlorophenyl)propylcarbamoyl]-6-(3-fluorophenyl)-4-oxoquinazolin-3-yl]acetate
Show/Hide
|
C27H23ClFN3O4
|
1
|
| 1 |
IC50 = 3240 nM
|
|
|
|
CP0557867
|
methyl 2-[6-(3-fluorophenyl)-4-oxo-7-[2-[[4-(trifluoromethyl)phenyl]methoxy]ethylcarbamoyl]quinazolin-3-yl]acetate
Show/Hide
|
C28H23F4N3O5
|
1
|
| 1 |
IC50 = 3460 nM
|
|
|
|
CP0487884
|
butyl 2-[2-(4-cyanobenzoyl)-7-methyl-1,1-dioxo-3H-1,2-benzothiazol-3-yl]acetate
Show/Hide
|
C22H22N2O5S
|
1
|
| 1 |
IC50 = 3830 nM
|
|
|
|
CP0552889
|
methyl 2-[6-[4-(dimethylamino)phenoxy]-4-oxo-7-[4-[4-(trifluoromethyl)phenoxy]butanoylamino]quinazolin-3-yl]acetate
Show/Hide
|
C30H29F3N4O6
|
1
|
| 1 |
IC50 = 3870 nM
|
|
|
|
CP0450892
|
6-(3-fluorophenyl)-4-oxo-N-[2-[[4-(trifluoromethyl)phenyl]methoxy]ethyl]-3H-quinazoline-7-carboxamide
Show/Hide
|
C25H19F4N3O3
|
1
|
| 1 |
IC50 = 4110 nM
|
|
|
|
CP0450902
|
methyl 2-[7-[[2-[(4-chlorophenyl)methoxy]acetyl]amino]-6-[3-(dimethylamino)phenoxy]-4-oxoquinazolin-3-yl]acetate
Show/Hide
|
C28H27ClN4O6
|
1
|
| 1 |
IC50 = 4310 nM
|
|
|
|
CP0557802
|
4-oxo-6-[3-(trifluoromethyl)phenyl]-N-[2-[[4-(trifluoromethyl)phenyl]methoxy]ethyl]-3H-quinazoline-7-carboxamide
Show/Hide
|
C26H19F6N3O3
|
1
|
| 1 |
IC50 = 4390 nM
|
|
|
|
CP0450903
|
N-[6-[3-(dimethylamino)phenoxy]-4-oxo-3H-quinazolin-7-yl]-4-[4-(trifluoromethyl)phenoxy]butanamide
Show/Hide
|
C27H25F3N4O4
|
1
|
| 1 |
IC50 = 5640 nM
|
|
|
|
CP0565105
|
butyl 2-[4-fluoro-7-methyl-1,1-dioxo-2-[4-(trifluoromethyl)benzoyl]-3H-1,2-benzothiazol-3-yl]acetate
Show/Hide
|
C22H21F4NO5S
|
1
|
| 1 |
IC50 = 5820 nM
|
|
|
|
CP0552234
|
butyl 2-[4,7-dimethoxy-1,1-dioxo-2-[4-(trifluoromethyl)benzoyl]-3H-1,2-benzothiazol-3-yl]acetate
Show/Hide
|
C23H24F3NO7S
|
1
|
| 1 |
IC50 = 7140 nM
|
|
|
|
CP0478986
|
tert-butyl 2-[7-methyl-1,1-dioxo-2-[4-(trifluoromethyl)benzoyl]-3H-1,2-benzothiazol-3-yl]acetate
Show/Hide
|
C22H22F3NO5S
|
1
|
| 1 |
IC50 = 8120 nM
|
|
|
|
CP0487893
|
butyl 2-[6-chloro-7-methyl-1,1-dioxo-2-[4-(trifluoromethyl)benzoyl]-3H-1,2-benzothiazol-3-yl]acetate
Show/Hide
|
C22H21ClF3NO5S
|
1
|
| 1 |
IC50 = 8370 nM
|
|
|
|
CP0418676
|
butyl 2-[5-fluoro-7-methyl-1,1-dioxo-2-[4-(trifluoromethyl)benzoyl]-3H-1,2-benzothiazol-3-yl]acetate
Show/Hide
|
C22H21F4NO5S
|
1
|
| 1 |
IC50 = 9030 nM
|
|
|
|
CP0546026
|
2-[(4-cyanophenyl)methoxy]-N-[6-[3-(dimethylamino)phenoxy]-4-oxo-3H-quinazolin-7-yl]acetamide
Show/Hide
|
C26H23N5O4
|
1
|
| 1 |
IC50 = 9330 nM
|
|
|
