| Compound ID |
Compound Name |
Compound Formula |
|
CP0248635
|
1-[(E)-4-[5-carbamoyl-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-(3-morpholin-4-ylpropoxy)benzimidazol-1-yl]but-2-enyl]-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-methoxybenzimidazole-5-carboxamide
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|
C42H51N13O7
|
1
|
| 1 |
EC50 < 0.1 nM
|
|
|
|
CP0228629
|
2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-1-[(E)-4-[2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-methoxy-5-(1H-1,2,4-triazol-5-yl)benzimidazol-1-yl]but-2-enyl]-7-(3-morpholin-4-ylpropoxy)benzimidazole-5-carboxamide
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|
C43H51N15O6
|
1
|
| 1 |
EC50 = 240 nM
|
|
|
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CP0470946
|
2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-1-[(E)-4-[2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-(3-morpholin-4-ylpropoxy)-5-(1H-1,2,4-triazol-5-yl)benzimidazol-1-yl]but-2-enyl]-7-methoxybenzimidazole-5-carboxamide
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|
C43H51N15O6
|
1
|
| 1 |
EC50 = 330 nM
|
|
|
|
CP0470936
|
2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-1-[(E)-4-[2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-5-(1H-imidazol-2-yl)-7-(3-morpholin-4-ylpropoxy)benzimidazol-1-yl]but-2-enyl]-7-methoxybenzimidazole-5-carboxamide
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|
C44H52N14O6
|
1
|
| 1 |
EC50 = 790 nM
|
|
|
|
CP0470945
|
1-[(E)-4-[5-cyano-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-(3-morpholin-4-ylpropoxy)benzimidazol-1-yl]but-2-enyl]-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-methoxybenzimidazole-5-carboxamide
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|
C42H49N13O6
|
1
|
| 1 |
EC50 = 1020 nM
|
|
|
|
CP0419239
|
1-[(E)-4-[5-(4,5-dihydro-1,3-oxazol-2-yl)-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-methoxybenzimidazol-1-yl]but-2-enyl]-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-(3-morpholin-4-ylpropoxy)benzimidazole-5-carboxamide
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|
C44H53N13O7
|
1
|
| 1 |
EC50 = 1540 nM
|
|
|
|
CP0548400
|
2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-1-[(E)-4-[2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-methoxy-5-(5-methyl-1H-1,2,4-triazol-3-yl)benzimidazol-1-yl]but-2-enyl]-7-(3-morpholin-4-ylpropoxy)benzimidazole-5-carboxamide
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|
C44H53N15O6
|
1
|
| 1 |
EC50 = 2550 nM
|
|
|
|
CP0549128
|
2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-1-[(E)-4-[2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-methoxy-5-(1H-1,2,4-triazol-5-yl)benzimidazol-1-yl]but-2-enyl]-7-(3-hydroxypropoxy)benzimidazole-5-carboxamide
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|
C39H44N14O6
|
1
|
| 1 |
EC50 = 2660 nM
|
|
|
|
CP0533490
|
2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-1-[(E)-4-[2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-5-(1H-imidazol-2-yl)-7-methoxybenzimidazol-1-yl]but-2-enyl]-7-(3-morpholin-4-ylpropoxy)benzimidazole-5-carboxamide
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|
C44H52N14O6
|
1
|
| 1 |
EC50 = 3280 nM
|
|
|
|
CP0419240
|
N-[5-cyano-1-[(E)-4-[2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-methoxy-5-(1H-1,2,4-triazol-5-yl)benzimidazol-1-yl]but-2-enyl]-7-(3-morpholin-4-ylpropoxy)benzimidazol-2-yl]-2-ethyl-5-methylpyrazole-3-carboxamide
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|
C43H49N15O5
|
1
|
| 1 |
EC50 = 26000 nM
|
|
|
|
CP0533491
|
methyl 4-[5-carbamoyl-1-[(E)-4-[5-carbamoyl-2-(4-methoxy-4-oxobutanoyl)-7-(3-morpholin-4-ylpropoxy)benzimidazol-1-yl]but-2-enyl]-7-methoxybenzimidazol-2-yl]-4-oxobutanoate
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|
C38H45N7O11
|
1
|
| 1 |
EC50 = 29100 nM
|
|
|
|
CP0534058
|
N-[5-cyano-1-[(E)-4-[5-cyano-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-(3-morpholin-4-ylpropoxy)benzimidazol-1-yl]but-2-enyl]-7-methoxybenzimidazol-2-yl]-2-ethyl-5-methylpyrazole-3-carboxamide
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|
C42H47N13O5
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
|
CP0953743
|
(E)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carbonylimino)-1-((1r,4r)-4-((E)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carbonylimino)-7-methoxy-5-(1H-1,2,4-triazol-5-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)cyclohexyl)-7-(3-morpholinopropoxy)-2,3-dihydro-1H-benzo[d]imidazole-5-carboxamide
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|
C45H55N15O6
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
