Brief Information of the Cell Line and Protein
Cell Line ID: CL000547 , HEK-Blue hTLR4
Synonyms
HEK-BLUE-hTLR4
HEK293-Blue-hTLR4 CD14-MD2
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_IM82
Protein ID: PT03343 , Toll-like receptor 4
Gene Name TLR4
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID O00206
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000547  Protein ID: PT03343
 
Compound ID Compound Name Compound Formula
CP0575508
2-[3-[(E)-2-nitroethenyl]phenyl]pyridine
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C13H10N2O2
 1
1
IC50 = 280 nM
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CP0495410
N-[3-[(E)-2-nitroethenyl]phenyl]pyridin-2-amine
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C13H11N3O2
 1
1
IC50 = 460 nM
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CP0572017
2-[3-[(E)-2-nitroethenyl]phenoxy]pyridine
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C13H10N2O3
 1
1
IC50 = 1000 nM
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CP0534993
2-[[3-[(E)-2-nitroethenyl]phenoxy]methyl]pyridine
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C14H12N2O3
 1
1
IC50 = 1400 nM
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CP0575511
2-[3-[(E)-2-nitroethenyl]phenoxy]-1,3-thiazole
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C11H8N2O3S
 1
1
IC50 = 2400 nM
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CP0572019
1-(cyclopropylmethoxy)-3-[(E)-2-nitroethenyl]benzene
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C12H13NO3
 1
1
IC50 = 2500 nM
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CP0576164
1-[(E)-2-nitroethenyl]-2-phenoxybenzene
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C14H11NO3
 1
1
IC50 = 2500 nM
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CP0542843
N-[3-[(E)-2-nitroethenyl]phenyl]pyrimidin-2-amine
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C12H10N4O2
 1
1
IC50 = 2800 nM
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CP0570943
N-[3-[(E)-2-nitroethenyl]phenyl]pyridin-3-amine
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C13H11N3O2
 1
1
IC50 = 3100 nM
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CP0235971
1-[(E)-2-nitroethenyl]-3-phenylmethoxybenzene
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C15H13NO3
 1
1
IC50 = 3500 nM
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CP0542841
3-[(E)-2-nitroethenyl]-N-pyridin-2-ylbenzamide
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C14H11N3O3
 1
1
IC50 = 3600 nM
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CP0534995
butyl 6-[[3-[(E)-2-nitroethenyl]phenoxy]methyl]pyridine-3-carboxylate
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C19H20N2O5
 1
1
IC50 = 3700 nM
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CP0544423
1-N,1-N-dimethyl-4-[(E)-2-nitroethenyl]-2-N-pyridin-2-ylbenzene-1,2-diamine
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C15H16N4O2
 1
1
IC50 = 3700 nM
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CP0534994
4-[[3-[(E)-2-nitroethenyl]phenoxy]methyl]pyridine
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C14H12N2O3
 1
1
IC50 = 3900 nM
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CP0109265
1-[(4-fluorophenyl)methoxy]-3-[(E)-2-nitroethenyl]benzene
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C15H12FNO3
 1
1
IC50 = 4200 nM
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CP0569934
1-[(E)-2-nitroethenyl]-3-phenoxybenzene
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C14H11NO3
 1
1
IC50 = 4300 nM
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CP0575808
2-[[3-[(E)-2-nitroethenyl]phenoxy]methyl]naphthalene
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C19H15NO3
 1
1
IC50 = 4400 nM
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CP0235970
1-[(4-chlorophenyl)methoxy]-3-[(E)-2-nitroethenyl]benzene
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C15H12ClNO3
 1
1
IC50 = 4800 nM
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CP0572018
1-[(4-methoxyphenyl)methoxy]-3-[(E)-2-nitroethenyl]benzene
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C16H15NO4
 1
1
IC50 = 5600 nM
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CP0569933
1-butoxy-3-[(E)-2-nitroethenyl]benzene
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C12H15NO3
 1
1
IC50 = 5800 nM
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CP0570942
1-(cyclohexylmethoxy)-3-[(E)-2-nitroethenyl]benzene
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C15H19NO3
 1
1
IC50 = 5900 nM
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CP0572718
propyl 6-[[3-[(E)-2-nitroethenyl]phenoxy]methyl]pyridine-3-carboxylate
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C18H18N2O5
 1
1
IC50 = 5900 nM
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CP0575977
2-[3-[(E)-2-nitroethenyl]phenoxy]pyrimidine
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C12H9N3O3
 1
1
IC50 = 6200 nM
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CP0534992
1-[(E)-1-nitroprop-1-en-2-yl]-3-phenoxybenzene
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C15H13NO3
 1
1
IC50 = 6300 nM
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CP0575220
1-[(E)-2-nitroethenyl]-4-phenoxybenzene
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C14H11NO3
 1
1
IC50 = 6500 nM
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CP0572020
ethyl 6-[[3-[(E)-2-nitroethenyl]phenoxy]methyl]pyridine-3-carboxylate
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C17H16N2O5
 1
1
IC50 = 9200 nM
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