Brief Information of the Cell Line and Protein
Cell Line ID: CL000013 , Sf9
Synonyms
SF9
sf9
SF-9
Sf-9
sf-9
Sf 9
Spodoptera frugiperda clone 9
Sf clone 9
IPLB-Sf-9AE
IPLB-SF-9AE
IPLB-SF-9
IPLB-Sf-9
IPLB-Sf9
Category Spontaneously immortalized cell line
Organism
Spodoptera frugiperda (Fall armyworm)
Cellosaurus ID
CVCL_0549
Protein ID: PT02653 , N-lysine methyltransferase SMYD2
Gene Name SMYD2
Organism Homo sapiens, Human
Protein Classification Epigenetic regulator
Uniprot ID Q9NRG4
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000013  Protein ID: PT02653
 
Compound ID Compound Name Compound Formula
CP0402306
[3-(6-amino-2-methylpurin-9-yl)azetidin-1-yl]-[1-[(1-cyclohept-2-en-1-ylpiperidin-4-yl)methyl]pyrrol-3-yl]methanone
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C27H36N8O
 2
1
IC50 = 6 nM
   TI
   LI
   LO
   TS
2
IC50 = 23 nM
   TI
   LI
   LO
   TS
CP0096816
[3-(4-amino-6-methylimidazo[4,5-c]pyridin-1-yl)-3-methylazetidin-1-yl]-[1-[[1-[(1R)-cyclohept-2-en-1-yl]piperidin-4-yl]methyl]pyrrol-3-yl]methanone
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C29H39N7O
 2
1
IC50 = 8 nM
   TI
   LI
   LO
   TS
2
IC50 = 16 nM
   TI
   LI
   LO
   TS
CP0518358
[3-(6-amino-2-methylpurin-9-yl)azetidin-1-yl]-[1-[(1-cycloheptylpiperidin-4-yl)methyl]pyrrol-3-yl]methanone
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C27H38N8O
 2
1
IC50 = 23 nM
   TI
   LI
   LO
   TS
2
IC50 = 4000 nM
   TI
   LI
   LO
   TS
CP0402396
[3-(6-amino-2-methylpurin-9-yl)azetidin-1-yl]-[5-[(1-cycloheptylpiperidin-4-yl)methyl]-1-methylpyrazol-3-yl]methanone
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C27H39N9O
 2
1
IC50 = 32 nM
   TI
   LI
   LO
   TS
2
IC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0383124
[3-(6-amino-2-methylpurin-9-yl)azetidin-1-yl]-[5-[(4-cycloheptylpiperazin-1-yl)methyl]-1-methylpyrazol-3-yl]methanone
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C26H38N10O
 2
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
2
IC50 = 7000 nM
   TI
   LI
   LO
   TS
CP0402305
[3-(6-amino-2-methylpurin-9-yl)-3-methylazetidin-1-yl]-[5-[(4-cycloheptylpiperazin-1-yl)methyl]-1-methylpyrazol-3-yl]methanone
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C27H40N10O
 2
1
IC50 = 58 nM
   TI
   LI
   LO
   TS
2
IC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0492185
[3-(6-aminopurin-9-yl)azetidin-1-yl]-[1-methyl-5-[(4-propan-2-ylpiperazin-1-yl)methyl]pyrazol-3-yl]methanone
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C21H30N10O
 1
1
IC50 = 760 nM
   TI
   LI
   LO
   TS