| Compound ID |
Compound Name |
Compound Formula |
|
CP0420753
|
CHEMBL4542928
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|
C25H33N5O
|
1
|
| 1 |
IC50 = 4.37 nM
|
|
|
|
CP0424289
|
5-[4-[[hexyl(methyl)amino]methyl]phenyl]-7-oxo-6-propan-2-yl-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile
Show/Hide
|
C24H31N5O
|
1
|
| 1 |
IC50 = 22.7 nM
|
|
|
|
CP0396098
|
US10022354, Example 29
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|
C15H22N4O2
|
2
|
| 1 |
IC50 = 45 nM
|
|
|
| 2 |
IC50 = 570 nM
|
|
|
|
CP0530150
|
5-[3-[[hexyl(methyl)amino]methyl]phenyl]-7-oxo-6-propan-2-yl-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile
Show/Hide
|
C24H31N5O
|
1
|
| 1 |
IC50 = 65.3 nM
|
|
|
|
CP0546755
|
N-[1-(5-propan-2-yl-1H-pyrazole-3-carbonyl)pyrrolidin-3-yl]benzamide
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|
C18H22N4O2
|
1
|
| 1 |
IC50 = 99 nM
|
|
|
|
CP0068188
|
2-{5-[(4-fluorobenzyl)oxy]-1H- pyrazol-1-yl}pyridine-4- carboxylic acid
Show/Hide
|
C16H12FN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0068190
|
2-[5-[1-(4- fluorophenyl)ethoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H14FN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0068191
|
2-[5-[(4-chloro-2- methoxyphenyl)methoxy]pyrazol- 1-yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H14ClN3O4
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0080560
|
2-{5-[(2-fluorobenzyl)oxy]-1H- pyrazol-1-yl}pyridine-4- carboxylic acid
Show/Hide
|
C16H12FN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0080562
|
2-[4-ethyl-5-[(4- fluorophenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
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|
C18H16FN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0080564
|
2-{5-[(4-chloro-2- fluorobenzyl)oxy]-1H-pyrazol-1- yl}pyridine-4-carboxylic acid
Show/Hide
|
C16H11ClFN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0080566
|
2-(5-((4-chloro-2-methylbenzyl)oxy)-1Hpyrazol-1-yl)isonicotinic acid (N19)
Show/Hide
|
C17H14ClN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0080567
|
2-{5-[(4-methylbenzyl)oxy]-1H- pyrazol-1-yl}pyridine-4- carboxylic acid
Show/Hide
|
C17H15N3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0080570
|
2-(5-(4-(methylsulfonyl)phenyl)- 1H-pyrazol-1-yl)isonicotinic acid
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|
C16H13N3O4S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0081047
|
2-(5-(3,4-difluorophenyl)-1H- pyrazol-1-yl)isonicotinic acid
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|
C15H9F2N3O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0081048
|
2-{5-[(4-bromobenzyl)oxy]-1H- pyrazol-1-yl}pyridine-4- carboxylic acid
Show/Hide
|
C16H12BrN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0081050
|
2-(4-[2-(dimethylamino)ethyl]- 5-[(4- fluorophenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C20H21FN4O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0081052
|
2-(5-(3-hydroxy-4-methylphenyl)- 1H-pyrazol-1-yl)isonicotinic acid
Show/Hide
|
C16H13N3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0081054
|
2-(5-(benzyloxy)-1H-pyrazol-1- yl)isonicotinic acid
Show/Hide
|
C16H13N3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0081057
|
2-[5-[(4-chloro-2- ethoxyphenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H16ClN3O4
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0111516
|
2-{5-[(4-ethylbenzyl)oxy]- 1H-pyrazol-1-yl}pyridine- 4-carboxylic acid
Show/Hide
|
C18H17N3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0111518
|
2-(5-(3-hydroxyphenyl)-1H- pyrazol-1-yl)isonicotinic acid
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|
C15H11N3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0120868
|
2-[5-[(4-chlorophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylic acid
Show/Hide
|
C16H12ClN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0120871
|
2-[5-[(4-chloro-2- phenylmethoxyphenyl)methoxy] pyrazol-1-yl]pyridine-4-carboxylic acid
Show/Hide
|
C23H18ClN3O4
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0237640
|
2-(5-(4-hydroxyphenyl)-1H- pyrazol-1-yl)isonicotinic acid
Show/Hide
|
C15H11N3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0237641
|
2-(5-p-tolyl-1H-pyrazol-1- yl)isonicotinic acid
Show/Hide
|
C16H13N3O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0239479
|
2-{5-[(4-methoxybenzyl)oxy]-1H- pyrazol-1-yl}pyridine-4- carboxylic acid
Show/Hide
|
C17H15N3O4
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0239480
|
2-{5-[(4-cyclopropylbenzyl)oxy]- 1H-pyrazol-1-yl}pyridine-4- carboxylic acid
Show/Hide
|
C19H17N3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0239481
|
2-[5-[(4-fluorophenyl)methoxy]-4-(2-hydroxyethyl)pyrazol-1-yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H16FN3O4
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0239483
|
2-(5-(3-methoxy-4-methylphenyl)- 1H-pyrazol-1-yl)isonicotinic acid
Show/Hide
|
C17H15N3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0248899
|
2-(5-(4-fluorophenyl)-1H-pyrazol- 1-yl)isonicotinic acid
Show/Hide
|
C15H10FN3O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0248901
|
2-[5-[[4-chloro-2- (cyclopropylmethoxy(phenyl] methoxy]pyrazol-1-yl]pyridine- 4-carboxylic acid
Show/Hide
|
C20H18ClN3O4
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0315103
|
2-[5-[(4- cyanophenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H12N4O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0329706
|
2-[5-[(4-fluorophenyl)methoxy]-4- methylpyrazol-1-yl]pyridine-4- carboxylic acid
Show/Hide
|
C17H14FN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0353574
|
2-(5-{[4- (trifluoromethyl)benzyl]oxy}- 1H-pyrazol-1-yl)pyridine-4- carboxylic acid
Show/Hide
|
C17H12F3N3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0364520
|
2-(5-(3-fluorophenyl)-1H-pyrazol- 1-yl)isonicotinic acid
Show/Hide
|
C15H10FN3O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0387100
|
N-cyano-2-[4-[2-[(4- fluorophenyl)methyl- methylamino]ethyl]pyrazol-1- yl]pyridine-4-carboxamide
Show/Hide
|
C20H19FN6O
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0392128
|
2-[5-[(2-cyano-4- methylphenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H14N4O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0392132
|
2-(5-(4-chloro-3-hydroxyphenyl)- 1H-pyrazol-1-yl)isonicotinic acid
Show/Hide
|
C15H10ClN3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0392133
|
2-[5-[(3-chloro-4- ethylphenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H16ClN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0392134
|
2-[5-[(5-chloro-2,3-dihydro-1H- inden-1-yl)oxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H14ClN3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0392138
|
2-(3-phenethyl-1H-pyrazol-1- yl)isonicotinic acid
Show/Hide
|
C17H15N3O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0392139
|
2-{5-[(3-fluorobenzyl)oxy]-1H- pyrazol-1-yl}pyridine-4- carboxylic acid
Show/Hide
|
C16H12FN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0392140
|
2-{5-[(3-hydroxybenzyl)oxy]-1H- pyrazol-1-yl}pyridine-4- carboxylic acid
Show/Hide
|
C16H13N3O4
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0392141
|
2-[5-[[4-chloro-3- (trifluoromethyl)phenyl]methoxy] pyrazol-1-yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H11ClF3N3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0392143
|
2-[5-[(2-butoxy-4- chlorophenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C20H20ClN3O4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0392157
|
2-[5-(1H-indazol-6-yl)-1H- pyrazol-1-yl]pyridine-4-carboxylic acid
Show/Hide
|
C16H11N5O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0392168
|
2-[5-[(2-methoxy-4- methylphenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H17N3O4
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0393362
|
2-(5-hydroxy-3,4- dimethyl-1H-pyrazol-1- yl)isonicotinic acid
Show/Hide
|
C11H11N3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0393367
|
2-[5-[(6-chloro-1,2,3,4- tetrahydronaphthalen-1- yl)oxy]pyrazol-1-yl]pyridine-4- carboxylic acid
Show/Hide
|
C19H16ClN3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0393384
|
2-[5-[(4-fluoro-2- methylphenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H14FN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0393485
|
2-{5-[(3-chlorobenzyl)oxy]-1H- pyrazol-1-yl}pyridine-4- carboxylic acid
Show/Hide
|
C16H12ClN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0393486
|
2-[5-[(2-ethyl-4- methylphenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C19H19N3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0393487
|
2-[5-[[4-chloro-2-(1- phenylethoxy)phenyl]methoxy] pyrazol-1-yl]pyridine-4-carboxylic acid
Show/Hide
|
C24H20ClN3O4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0405016
|
2-[5-[(2-chloro-4- cyclopropylphenyl)methoxy] pyrazol-1-yl]pyridine-4-carboxylic acid
Show/Hide
|
C19H16ClN3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0405017
|
2-[5-[[4-chloro-2-(2- methoxyethoxy)phenyl]methoxy] pyrazol-1-yl]pyridine-4-carboxylic acid
Show/Hide
|
C19H18ClN3O5
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0405018
|
2-[5-[[4-chloro-2-[(E)-2-(4- fluorophenyl)ethenyl]phenyl] methoxy]pyrazol-1-yl]pyridine- 4-carboxylic acid
Show/Hide
|
C24H17ClFN3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0405019
|
2-[5-[(2-chloro-4- methylphenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H14ClN3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0405148
|
2-{5-[(1-methyl-1H-indazol-6- yl)methoxy]-1H-pyrazol-1- yl}pyridine-4-carboxylic acid
Show/Hide
|
C18H15N5O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0405150
|
2-[5-[(3-fluoro-4- methylphenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H14FN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0405251
|
2-{5-[(4,4- difluorocyclohexyl)methoxy]-1H- pyrazol-1-yl}pyridine-4- carboxylic acid
Show/Hide
|
C16H17F2N3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0411547
|
2-[5-[[4-fluoro-2-[(4- fluorophenyl)methoxy]phenyl] methoxy]pyrazol-1-yl]pyridine- 4-carboxylic acid
Show/Hide
|
C23H17F2N3O4
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0411548
|
2-[5-[[4-fluoro-2-[(E)-2-(4- fluorophenyl)ethenyl]phenyl] methoxy]pyrazol-1-yl]pyridine- 4-carboxylic acid
Show/Hide
|
C24H17F2N3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0411551
|
2-(5-hydroxy-3-(methoxymethyl)- 1H-pyrazol-1-yl)isonicotinic acid
Show/Hide
|
C11H11N3O4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0411552
|
2-[5-[[4-fluoro-3-[(4- fluorophenyl)methoxy]phenyl] methoxy]pyrazol-1-yl]pyridine- 4-carboxylic acid
Show/Hide
|
C23H17F2N3O4
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0411553
|
2-[5-[(4-bromo-2- methylphenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H14BrN3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0411605
|
2-[5-[(4-iodo-2- methylphenyl)methoxy]pyrazol- 1-yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H14IN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0411618
|
2-(5-(3-hydroxy-4- (methylsulfonyl)phenyl)-1H- pyrazol-1-yl)isonicotinic acid
Show/Hide
|
C16H13N3O5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0411619
|
2-{5-[4-(dimethylamino)phenyl]- 1H-pyrazol-1-yl}pyridine-4- carboxylic acid
Show/Hide
|
C17H16N4O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0445661
|
2-[5-[[4-fluoro-2-(1- phenylethoxy)phenyl]methoxy] pyrazol-1-yl]pyridine-4-carboxylic acid
Show/Hide
|
C24H20FN3O4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0445662
|
2-[5-[(5-fluoro-2,3-dihydro-1H- inden-1-yl)oxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H14FN3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0445663
|
2-[5-[(4-ethyl-2- fluorophenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H16FN3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0445664
|
2-[5-[(4-cyclopropyl-2- fluorophenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C19H16FN3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0455415
|
2-[5-[(4-iodo-2- methoxyphenyl)methoxy]pyrazol- 1-yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H14IN3O4
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0455416
|
2-[4-(2-[(4-fluorophenyl)methyl- methylamino]ethyl]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C19H19FN4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0455417
|
2-(5-methyl-4-phenyl-1H-pyrazol- 1-yl)isonicotinic acid
Show/Hide
|
C16H13N3O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0457403
|
2-{5-[(3,4- difluorobenzyl)oxy]-1H- pyrazol-1-yl}pyridine-4- carboxylic acid
Show/Hide
|
C16H11F2N3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0457405
|
2-{5-[(3-chloro-4- fluorobenzyl)oxy]-1H-pyrazol-1- yl}pyridine-4-carboxylic acid
Show/Hide
|
C16H11ClFN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0457407
|
2-[5-[[4-chloro-2-[(4- fluorophenyl)methoxy]phenyl] methoxy]pyrazol-1-yl]pyridine- 4-carboxylic acid
Show/Hide
|
C23H17ClFN3O4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0457408
|
2-(5-hydroxy-3-methyl-1H- pyrazol-1-yl)isonicotinic acid
Show/Hide
|
C10H9N3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0458278
|
2-[5-[[4-fluoro-2-[2-(4- fluorophenyl)ethyl]phenyl] methoxy]pyrazol-1-yl]pyridine- 4-carboxylic acid
Show/Hide
|
C24H19F2N3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0458279
|
2-[5-[(2-ethyl-4- fluorophenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H16FN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0458280
|
2-[5-[(6-fluoro-1,2,3,4- tetrahydronaphthalen-1- yl)oxy]pyrazol-1-yl)pyridine-4- carboxylic acid
Show/Hide
|
C19H16FN3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0458281
|
2-[5-[(4-cyclopropyl-3- fluorophenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C19H16FN3O3
|
1
|
| 1 |
IC50 = 100 nM
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CP0458284
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2-(3-butyl-1H-pyrazol-1-yl)pyridine-4-carboxylic acid
Show/Hide
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C13H15N3O2
|
1
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| 1 |
IC50 = 100 nM
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CP0458285
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2-[5-[[4-chloro-3-[(4- fluorophenyl)methoxy]phenyl] methoxy]pyrazol-1-yl]pyridine- 4-carboxylic acid
Show/Hide
|
C23H17ClFN3O4
|
1
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| 1 |
IC50 <= 100 nM
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CP0476901
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2-[5-(2,3-dihydro-1-benzofuran-7- ylmethoxy)pyrazol-1-yl]pyridine- 4-carboxylic acid
Show/Hide
|
C18H15N3O4
|
1
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| 1 |
IC50 <= 100 nM
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CP0476902
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2-[5-[(4-cyano-2- methylphenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
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C18H14N4O3
|
1
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| 1 |
IC50 <= 100 nM
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CP0478919
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2-[5-[(2-butan-2-yloxy-4- chlorophenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
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C20H20ClN3O4
|
1
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| 1 |
IC50 = 100 nM
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CP0484265
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2-[5-[[4-chloro-3- (cyclopropylmethoxy)phenyl] methoxy]pyrazol-1-yl]pyridine- 4-carboxylic acid
Show/Hide
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C20H18ClN3O4
|
1
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| 1 |
IC50 = 100 nM
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CP0484266
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2-[5-[(3-chloro-4- cyclopropylphenyl)methoxy] pyrazol-1-yl]pyridine-4-carboxylic acid
Show/Hide
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C19H16ClN3O3
|
1
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| 1 |
IC50 = 100 nM
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CP0484267
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2-(3-benzyl-5-hydroxy-1H- pyrazol-1-yl)isonicotinic acid
Show/Hide
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C16H13N3O3
|
1
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| 1 |
IC50 = 100 nM
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CP0484268
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2-(5-(4-bromophenyl)-1H-pyrazol- 1-yl)isonicotinic acid
Show/Hide
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C15H10BrN3O2
|
1
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| 1 |
IC50 = 100 nM
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CP0484274
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2-[5-[(4-bromo-2- methoxyphenyl)methoxy]pyrazol- 1-yl]pyridine-4-carboxylic acid
Show/Hide
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C17H14BrN3O4
|
1
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| 1 |
IC50 <= 100 nM
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CP0484275
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2-[5-[(2-chloro-4- ethylphenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
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C18H16ClN3O3
|
1
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| 1 |
IC50 = 100 nM
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CP0484281
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2-(5-(benzyloxy)-3-methyl-1H- pyrazol-1-yl)isonicotinic acid
Show/Hide
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C17H15N3O3
|
1
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| 1 |
IC50 = 100 nM
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CP0490857
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2-[5-[(2,4- dimethylphenyl)methoxy]pyrazol- 1-yl]pyridine-4-carboxylic acid
Show/Hide
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C18H17N3O3
|
1
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| 1 |
IC50 <= 100 nM
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CP0490858
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2-[5-[[4-chloro-3-(2,2,2- trifluoroethoxy)phenyl]methoxy] pyrazol-1-yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H13ClF3N3O4
|
1
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| 1 |
IC50 <= 100 nM
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CP0490867
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2-[5-[(3,4- dichlorophenyl)methoxy]pyrazol- 1-yl]pyridine-4-carboxylic acid
Show/Hide
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C16H11Cl2N3O3
|
1
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| 1 |
IC50 <= 100 nM
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CP0490878
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2-{5-[(3-bromobenzyl)oxy]-1H- pyrazol-1-yl}pyridine-4- carboxylic acid
Show/Hide
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C16H12BrN3O3
|
1
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| 1 |
IC50 <= 100 nM
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CP0490879
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2-[5-[(4-cyano-2- ethylphenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C19H16N4O3
|
1
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| 1 |
IC50 <= 100 nM
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CP0490880
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2-{5-[(3-methoxybenzyl)oxy]-1H- pyrazol-1-yl}pyridine-4- carboxylic acid
Show/Hide
|
C17H15N3O4
|
1
|
| 1 |
IC50 <= 100 nM
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CP0490882
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2-{5-[(4-chloro-3- fluorobenzyl)oxy]-1H-pyrazol-1- yl}pyridine-4-carboxylic acid
Show/Hide
|
C16H11ClFN3O3
|
1
|
| 1 |
IC50 <= 100 nM
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CP0513275
|
2-[5-[(2-fluoro-4- methylphenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H14FN3O3
|
1
|
| 1 |
IC50 <= 100 nM
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CP0513277
|
2-[3-amino-5-(4-methylphenyl)- 1H-pyrazol-1-yl]pyridine-4- carboxylic acid
Show/Hide
|
C16H14N4O2
|
1
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| 1 |
IC50 <= 100 nM
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CP0513300
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2-[5-[[4-chloro-2-(2- methylpropoxy)phenyl]methoxy] pyrazol-1-yl]pyridine-4-carboxylic acid
Show/Hide
|
C20H20ClN3O4
|
1
|
| 1 |
IC50 = 100 nM
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CP0530557
|
2-[5-[(3-chloro-4- methylphenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H14ClN3O3
|
1
|
| 1 |
IC50 <= 100 nM
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CP0530565
|
2-(5-hydroxy-3-propyl-1H- pyrazol-1-yl)isonicotinic acid
Show/Hide
|
C12H13N3O3
|
1
|
| 1 |
IC50 = 100 nM
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CP0530567
|
2-(5-(4-chloro-3-methoxyphenyl)- 1H-pyrazol-1-yl)isonicotinic acid
Show/Hide
|
C16H12ClN3O3
|
1
|
| 1 |
IC50 = 100 nM
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CP0530570
|
2-[5-(1H-indazol-6-ylmethoxy)- 1H-pyrazol-1-yl]pyridine-4- carboxylic acid
Show/Hide
|
C17H13N5O3
|
1
|
| 1 |
IC50 = 100 nM
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CP0530571
|
2-[5-[(2,4- dichlorophenyl)methoxy]pyrazol- 1-yl]pyridine-4-carboxylic acid
Show/Hide
|
C16H11Cl2N3O3
|
1
|
| 1 |
IC50 <= 100 nM
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CP0530574
|
2-[5-[(4-chloro-2-propan-2- yloxyphenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C19H18ClN3O4
|
1
|
| 1 |
IC50 = 100 nM
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CP0536155
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2-(3-cyclopropyl-5-hydroxy-1H- pyrazol-1-yl)isonicotinic acid
Show/Hide
|
C12H11N3O3
|
1
|
| 1 |
IC50 <= 100 nM
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CP0536156
|
2-(5-m-tolyl-1H-pyrazol-1- yl)isonicotinic acid
Show/Hide
|
C16H13N3O2
|
1
|
| 1 |
IC50 = 100 nM
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|
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CP0536157
|
2-(5-(2,4-difluorophenyl)-1H- pyrazol-1-yl)isonicotinic acid
Show/Hide
|
C15H9F2N3O2
|
1
|
| 1 |
IC50 = 100 nM
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|
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CP0536158
|
2-[5-(pyridin-3-ylmethoxy)-1H- pyrazol-1-yl]pyridine-4-carboxylic acid
Show/Hide
|
C15H12N4O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0536173
|
2-[5-[(2,4- difluorophenyl)methoxy]pyrazol- 1-yl]pyridine-4-carboxylic acid
Show/Hide
|
C16H11F2N3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0536174
|
2-[5-[(3- cyanophenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H12N4O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0536175
|
2-[5-[(3,3- difluorocyclobutyl)methoxy] pyrazol-1-yl]pyridine-4-carboxylic acid
Show/Hide
|
C14H13F2N3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0547337
|
2-[5-[(4-ethyl-3- fluorophenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H16FN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
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CP0547354
|
2-[5-[[4-chloro-2-[2-(4- fluorophenyl)ethyl]phenyl] methoxy]pyrazol-1-yl]pyridine- 4-carboxylic acid
Show/Hide
|
C24H19ClFN3O3
|
1
|
| 1 |
IC50 = 100 nM
|
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|
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CP0558731
|
2-[5-[(4-chloro-2- ethylphenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H16ClN3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0559141
|
2-(5-hydroxy-1H-pyrazol-1- yl)isonicotinic acid
Show/Hide
|
C9H7N3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
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CP0559145
|
2-[5-[(2,3-difluoro-4- methylphenyl)methoxy]pyrazol-1- yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H13F2N3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
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CP0559146
|
2-[5-[(2,2-dimethyl-3H-1- benzofuran-7-yl)methoxy]pyrazol- 1-yl]pyridine-4-carboxylic acid
Show/Hide
|
C20H19N3O4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0559147
|
2-[5-(pyridin-4-ylmethoxy)-1H- pyrazol-1-yl]pyridine-4-carboxylic acid
Show/Hide
|
C15H12N4O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0559613
|
2-[5-[[4-chloro-2-(2,2,2- trifluoroethoxy)phenyl]methoxy] pyrazol-1-yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H13ClF3N3O4
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
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CP0893663
|
2-{5-[(2-methyl-2H-indazol-5-yl)methoxy]-1H-pyrazol-1-yl}pyridine-4-carboxylic acid
Show/Hide
|
C18H15N5O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0383219
|
2-[1-(pyridin-2-ylmethyl)-1H- imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C15H12N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
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CP0383220
|
2-[1-(2-naphthalen-1- ylethyl)imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C21H17N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
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CP0383372
|
2-{1-[(4-methylmorpholin-2- yl)methyl]-1H-imidazol-4- yl}pyridine-4-carboxylic acid
Show/Hide
|
C15H18N4O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
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CP0383373
|
2-{1-[(1-methylpiperidin-3- yl)methyl]-1H-imidazol-4- yl}pyridine-4-carboxylic acid
Show/Hide
|
C16H20N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0393356
|
2-[5-(2,4-dichlorophenyl)-1- methyl-1H-imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C16H11Cl2N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0393357
|
2-{1-[2-(pyrrolidin-1-yl)ethyl]- 1H-imidazol-4-yl}pyridine-4- carboxylic acid
Show/Hide
|
C15H18N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0393358
|
2-(1-{2- [methyl(phenyl)amino]ethyl}-1H- imidazol-4-yl)pyridine-4- carboxylic acid
Show/Hide
|
C18H18N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0393359
|
2-[1-(1-phenylethyl)imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H15N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0393360
|
2-(1-methylimidazol-4-yl)pyridine-4-carboxylic acid
Show/Hide
|
C10H9N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0393361
|
2-[5-(4-tert-butylphenyl)-1- methyl-1H-imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C20H21N3O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0393364
|
2-{1-[3-(dimethylamino)propyl]- 1H-imidazol-4-yl}pyridine-4- carboxylic acid
Show/Hide
|
C14H18N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0393365
|
2-{1-[2-(1H-pyrazol-1-yl)ethyl]- 1H-imidazol-4-yl}pyridine-4- carboxylic acid
Show/Hide
|
C14H13N5O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0393366
|
2-[1-[2-[(4-chlorophenyl)methyl- cyclopropylamino]ethyl]imidazol- 4-yl]pyridine-4-carboxylic acid
Show/Hide
|
C21H21ClN4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0393529
|
2-[5-(4-chloro-3-fluorophenyl)-1- propyl-1H-imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H15ClFN3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0393530
|
2-[1-(tetrahydrofuran-2- ylmethyl)-1H-imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C14H15N3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0393531
|
2-{1-[2-(pyrrolidin-1-yl)propyl]- 1H-imidazol-4-yl}pyridine-4- carboxylic acid
Show/Hide
|
C16H20N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0393534
|
2-[1-[2-(4-chloro-1,3- dihydroisoindol-2- yl)ethyl]imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C19H17ClN4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0394363
|
2-[5-(4-chloro-3-fluorophenyl)-1- (2-methoxyethyl)-1H-imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H15ClFN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0394431
|
2-(1-{2- [(cyclopropylmethyl)(methyl)- amino]ethyl}-1H-imidazol-4- yl)pyridine-4-carboxylic acid
Show/Hide
|
C16H20N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0394432
|
2-[1-[2-[(4,4- difluorocyclohexyl)methylamino] ethyl]imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C18H22F2N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0394433
|
2-[1-[2-(1,3-dihydroisoindol-2- yl)ethyl]imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C19H18N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0394434
|
2-[1-[2-(6-fluoro-3,4-dihydro-2H- quinolin-1-yl)ethyl]imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C20H19FN4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0394435
|
2-[1-[2-(4- fluorophenyl)ethyl]imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H14FN3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0394436
|
2-[1-[(2- fluorophenyl)methyl]imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C16H12FN3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0394437
|
2-[1-[2-(3- chlorophenyl)ethyl]imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H14ClN3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0402457
|
2-[1-[2-(6-chloro-3,4-dihydro- 2H-quinolin-1-yl)ethyl]imidazol- 4-yl]pyridine-4-carboxylic acid
Show/Hide
|
C20H19ClN4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0402458
|
2-[1-[2-(2- methoxyphenyl)ethyl]imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H17N3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0402462
|
2-[5-(4-fluorophenyl)-1-methyl- 1H-imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C16H12FN3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0402463
|
2-(5-{4-[1- (methoxymethyl)cyclopropyl]- phenyl}-1-methyl-1H-imidazol-4- yl)pyridine-4-carboxylic acid
Show/Hide
|
C21H21N3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0405420
|
2-[1-(pyrrolidin-3-yl)-1H- imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C13H14N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0405421
|
2-[1-(pyrrolidin-2-ylmethyl)-1H- imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C14H16N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0407402
|
2-[5-(4-methoxyphenyl)-1-methylimidazol-4-yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H15N3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0411971
|
2-[1-[2-[methyl-[(3- methylphenyl)methyl]amino]ethyl]- imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C20H22N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0411972
|
2-[1-[2-[methyl-[[4- (trifluoromethyl)phenyl]methyl]- amino]ethyl]imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C20H19F3N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0411979
|
2-[1-[2-(2- chlorophenyl)ethyl]imidazol-4- yl]-4-(2H-tetrazol-5-yl)pyridine
Show/Hide
|
C17H14ClN7
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0411996
|
2-[5-[2-(cyclopropylmethoxy)-4- fluorophenyl]-1-methylimidazol- 4-yl]-4-(2H-tetrazol-5-yl)pyridine
Show/Hide
|
C20H18FN7O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0411997
|
2-[5-(3-hydroxy-4- methylphenyl)-1-methyl-1H- imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C17H15N3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0411998
|
2-{1-methyl-5-[4- (trifluoromethyl)phenyl]-1H- imidazol-4-yl}pyridine-4- carboxylic acid
Show/Hide
|
C17H12F3N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0412804
|
2-[1-(6-fluoro-2,3-dihydro-1H- inden-1-yl)imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H14FN3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0412805
|
2-[5-[2-(cyclopropylmethoxy)-4- fluorophenyl]-1-methylimidazol- 4-yl]pyridine-4-carboxylic acid
Show/Hide
|
C20H18FN3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0412806
|
2-[5-(4-ethylphenyl)-1-methyl- 1H-imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C18H17N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0412807
|
2-[5-(4-cyclopropylphenyl)-1- methyl-1H-imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C19H17N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0412824
|
2-{1-methyl-5-[3- (methylcarbamoyl)phenyl]-1H- imidazol-4-yl}pyridine-4- carboxylic acid
Show/Hide
|
C18H16N4O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0429897
|
2-{1-methyl-5-[4-(1H-pyrazol-1- yl)phenyl]-1H-imidazol-4- yl}pyridine-4-carboxylic acid
Show/Hide
|
C19H15N5O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0429898
|
2-[5-(4-chloro-2-ethoxyphenyl)- 1-methyl-1H-imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H16ClN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0429899
|
2-[5-(4-chloro-3-fluorophenyl)-1- (3-methoxypropyl)-1H-imidazol- 4-yl]pyridine-4-carboxylic acid
Show/Hide
|
C19H17ClFN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0432296
|
2-{1-methyl-5-[4- (trifluoromethoxy)phenyl]-1H- imidazol-4-yl}pyridine-4- carboxylic acid
Show/Hide
|
C17H12F3N3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0432297
|
2-[1-[2-[(4- fluorophenyl)methylamino]ethyl]- imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C18H17FN4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0432299
|
2-[1-[2-(2- chlorophenyl)ethyl]imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H14ClN3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0432306
|
2-{1-[2-(dimethylamino)ethyl]- 1H-imidazol-4-yl}pyridine-4- carboxylic acid
Show/Hide
|
C13H16N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0432307
|
2-(1-{2-[2- (dimethylamino)ethoxy]ethyl}- 1H-imidazol-4-yl)pyridine-4- carboxylic acid
Show/Hide
|
C15H20N4O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0432309
|
2-[1-[(2- chlorophenyl)methyl]imidazol-4- yl]-4-(2H-tetrazol-5-yl)pyridine
Show/Hide
|
C16H12ClN7
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0445675
|
2-[1-[2-(2- methylphenyl)ethyl]imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H17N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0445676
|
2-[1-(cyclohexylmethyl)imidazol- 4-yl]pyridine-4-carboxylic acid
Show/Hide
|
C16H19N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0445728
|
2-[1-[2-[(2- methoxyphenyl)methylamino]- ethyl]imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C19H20N4O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0445729
|
2-[1-[2-[(2- ethylphenyl)methylamino]ethyl]- imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C20H22N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0446230
|
2-[5-(3-chlorophenyl)-1-methyl- 1H-imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C16H12ClN3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0446231
|
2-{1-[2-(pyrrolidin-1-yl)ethyl]- 1H-imidazol-4-yl}-4-(2H- tetrazol-5-yl)pyridine
Show/Hide
|
C15H18N8
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0446232
|
2-[1-[2-(5-chloro-1,3- dihydroisoindol-2- yl)ethyl]imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C19H17ClN4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0446234
|
2-[1-(4-fluoro-2,3-dihydro-1H- inden-1-yl)imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H14FN3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0450692
|
2-(5-{4-[1- (hydroxymethyl)cyclopropyl]- phenyl}-1-methyl-1H-imidazol-4- yl)pyridine-4-carboxylic acid
Show/Hide
|
C20H19N3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0455739
|
2-(5-bromo-1-methyl-1H- imidazol-4-yl)pyridine-4- carboxylic acid
Show/Hide
|
C10H8BrN3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0455740
|
2-(1-propyl-1H-imidazol-4- yl)pyridine-4-carboxylic acid
Show/Hide
|
C12H13N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0455742
|
2-{1-[(1-methylpiperidin-4- yl)methyl]-1H-imidazol-4- yl}pyridine-4-carboxylic acid
Show/Hide
|
C16H20N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0455743
|
2-(1-methyl-1H-imidazol-4-yl)-4- (2H-tetrazol-5-yl)pyridine
Show/Hide
|
C10H9N7
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0455744
|
2-[1-[2-[cyclopropyl-[(4- fluorophenyl)methyl]amino]ethyl] imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C21H21FN4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0455745
|
2-[1-[2-[cyclopropyl-[(3,4- dichlorophenyl)methyl]amino]- ethyl]imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C21H20Cl2N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0455746
|
2-[5-(4-chlorophenyl)-1-methyl- 1H-imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C16H12ClN3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0455747
|
2-[5-(4-chloro-2-methylphenyl)- 1-methyl-1H-imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H14ClN3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0457628
|
2-{1-[2-(2-oxopyrrolidin-1- yl)ethyl]-1H-imidazol-4- yl}pyridine-4-carboxylic acid
Show/Hide
|
C15H16N4O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0457631
|
2-[1-[2-[(3,3- difluorocyclobutyl)methylamino] ethyl]imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C16H18F2N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0457638
|
2-[1-methyl-5-(4-methylphenyl)- 1H-imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C17H15N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0457639
|
2-[5-(4-ethynylphenyl)-1-methyl- 1H-imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C18H13N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0457640
|
2-[5-(1H-indol-6-yl)-1-methyl- 1H-imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C18H14N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0458100
|
2-[1-[2-(2-chlorophenyl)-2- methylpropyl]imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C19H18ClN3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0461691
|
2-[5-[4-(cyclopropylmethoxy)phenyl]-1-methylimidazol-4-yl]pyridine-4-carboxylic acid
Show/Hide
|
C20H19N3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0467776
|
2-[5-(3,4-dichlorophenyl)-1- methyl-1H-imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C16H11Cl2N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0467777
|
2-[1-[2-[[2- (trifluoromethyl)phenyl]methyl- amino]ethyl]imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C19H17F3N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0467778
|
2-[1-[2-(4- methoxyphenyl)ethyl]imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H17N3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0467779
|
2-[1-(2,3-dihydro-1H-inden-2- yl)imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C18H15N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0467780
|
2-[1-(2-cyclohexylethyl)imidazol- 4-yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H21N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0467783
|
N-cyano-2-(1-{2- [(cyclopropylmethyl)(methyl)- amino]ethyl}-1H-imidazol-4- yl)pyridine-4-carboxamide
Show/Hide
|
C17H20N6O
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0467785
|
2-[1-[2-[(2- chlorophenyl)methylamino]ethyl] imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C18H17ClN4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0467786
|
4-(2H-tetrazol-5-yl)-2-[1-[2-[2- (trifluoromethyl)phenyl]ethyl]- imidazol-4-yl]pyridine
Show/Hide
|
C18H14F3N7
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0467791
|
2-[1-(1-methylpiperidin-4-yl)-1H- imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C15H18N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0467794
|
2-[1-[2-[(3-fluorophenyl)methyl- methylamino]ethyl]imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C19H19FN4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0471463
|
2-[1-[2-(4-cyano-1,3- dihydroisoindol-2- yl)ethyl]imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C20H17N5O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0471464
|
2-[1-(2-methyl-1- phenylpropyl)imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C19H19N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0471505
|
2-[1-[2-[5-(trifluoromethyl)-1,3- dihydroisoindol-2- yl]ethyl]imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C20H17F3N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0471506
|
2-(1-benzylimidazol-4- yl)pyridine-4-carboxylic acid
Show/Hide
|
C16H13N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0471508
|
2-[1-[[2-chloro-3- (trifluoromethyl)phenyl]methyl]- imidazol-4-yl]-4-(2H-tetrazol-5- yl)pyridine
Show/Hide
|
C17H11ClF3N7
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0472102
|
2-{5-(4-chloro-3-fluorophenyl)-1- [2-(dimethylamino)ethyl]-1H- imidazol-4-yl}pyridine-4- carboxylic acid
Show/Hide
|
C19H18ClFN4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0472103
|
2-(1-{2- [benzyl(methyl)amino]ethyl}-1H- imidazol-4-yl)pyridine-4- carboxylic acid
Show/Hide
|
C19H20N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0472106
|
2-[1-[2-(2- fluorophenyl)ethyl]imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H14FN3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0473810
|
2-{1-methyl-5-[4-(pyrrolidin-1- yl)phenyl]-1H-imidazol-4- yl}pyridine-4-carboxylic acid
Show/Hide
|
C20H20N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0476937
|
2-[1-(1-phenylpropyl)imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H17N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0477133
|
2-{5-[4-chloro-2- (trifluoromethyl)phenyl]-1- methyl-1H-imidazol-4- yl}pyridine-4-carboxylic acid
Show/Hide
|
C17H11ClF3N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0477134
|
2-{5-[4-chloro-3- (trifluoromethyl)phenyl]-1- methyl-1H-imidazol-4- yl}pyridine-4-carboxylic acid
Show/Hide
|
C17H11ClF3N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0477135
|
2-[1-[2-(5-fluoro-1,3- dihydroisoindol-2- yl)ethyl]imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C19H17FN4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0477136
|
2-[1-[2-(3,4-dihydro-2H-quinolin- 1-yl)ethyl]imidazol-4-yl]pyridine- 4-carboxylic acid
Show/Hide
|
C20H20N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0477137
|
2-[1-[2-(5-fluoro-2,3- dihydroindol-1-yl)ethyl]imidazol- 4-yl]pyridine-4-carboxylic acid
Show/Hide
|
C19H17FN4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0477138
|
2-[1-[(4- fluorophenyl)methyl]imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C16H12FN3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0477139
|
2-[1-(1,2,3,4- tetrahydronaphthalen-1- ylmethyl)imidadzol-4-yl]pyridine- 4-carboxylic acid
Show/Hide
|
C20H19N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0481768
|
2-[5-(4-chloro-3-methoxyphenyl)- 1-methyl-1H-imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C17H14ClN3O3
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0481769
|
2-(1-methyl-5-{4-[1- (trifluoromethyl)cyclopropyl]- phenyl}-1H-imidazol-4-yl)pyridine- 4-carboxylic acid
Show/Hide
|
C20H16F3N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0481770
|
2-[1-[2-[(4-fluorophenyl)methyl- methylamino]ethyl]imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C19H19FN4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0481772
|
2-[1-[2-[2- (trifluoromethyl)phenyl]ethyl]- imidazol-4-yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H14F3N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0481773
|
2-[1-[(3- phenylphenyl)methyl]imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C22H17N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0487554
|
2-[5-(4-ethoxyphenyl)-1-methyl- 1H-imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C18H17N3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0493016
|
2-[1-(1-phenylpropan-2- yl)imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C18H17N3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0493024
|
2-[1-[2-[ethyl-[(4- fluorophenyl)methyl]amino]ethyl] imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C20H21FN4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0519471
|
2-[5-(4-chloro-3-fluorophenyl)-1- methyl-1H-imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C16H11ClFN3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0530625
|
2-{5-[3-(hydroxymethyl)phenyl]- 1-methyl-1H-imidazol-4- yl}pyridine-4-carboxylic acid
Show/Hide
|
C17H15N3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0530627
|
2-[1-[(3- fluorophenyl)methyl]imidazol-4- yl]pyridine-4-carboxylic
Show/Hide
|
C16H12FN3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0533865
|
2-[1-[2-(4-chloro-N- methylanilino)ethyl]imidazol-4- yl]pyridine-4-carboxylic acid
Show/Hide
|
C18H17ClN4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0534803
|
2-[5-(3-fluorophenyl)-1-methyl- 1H-imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C16H12FN3O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0536460
|
2-[1-[2-[methyl-[(4- methylphenyl)methyl]amino]ethyl]- imidazol-4-yl]pyridine-4- carboxylic acid
Show/Hide
|
C20H22N4O2
|
1
|
| 1 |
IC50 <= 100 nM
|
|
|
|
CP0865067
|
2-[1-(1-phenylpropyl)imidazol-4-yl]-4-(2H-tetrazol-5-yl)pyridine
Show/Hide
|
C18H17N7
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0883751
|
2-[1-(2-methyl-1-phenylpropyl)imidazol-4-yl]-4-(2H-tetrazol-5-yl)pyridine
Show/Hide
|
C19H19N7
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0563492
|
US10022354, Example 69
Show/Hide
|
C27H30N6O
|
1
|
| 1 |
IC50 = 105 nM
|
|
|
|
CP0407352
|
US10022354, Example 61
Show/Hide
|
C24H28N4O
|
1
|
| 1 |
IC50 = 122 nM
|
|
|
|
CP0558648
|
US10022354, Example 7
Show/Hide
|
C23H26N4O2
|
1
|
| 1 |
IC50 = 128 nM
|
|
|
|
CP0530149
|
2-[4-[2-[hexyl(methyl)amino]ethylcarbamoyl]pyridin-2-yl]pyridine-4-carboxylic acid
Show/Hide
|
C21H28N4O3
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0430260
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5-[5-[[hexyl(methyl)amino]methyl]thiophen-3-yl]-7-oxo-6-propan-2-yl-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile
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C22H29N5OS
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1
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| 1 |
IC50 = 179 nM
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CP0414175
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US10022354, Example 168
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C16H26N4O2
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1
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| 1 |
IC50 = 198 nM
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CP0407289
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2-methyl-N-[1-(5-propan-2-yl-1H-pyrazole-3-carbonyl)pyrrolidin-3-yl]propanamide
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C15H24N4O2
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1
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| 1 |
IC50 = 204 nM
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CP0517788
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US10022354, Example 123
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C14H22N4O2
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1
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| 1 |
IC50 = 251 nM
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CP0407351
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US10022354, Example 70
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C21H24N4O2
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1
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| 1 |
IC50 = 265 nM
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CP0360983
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2-[(2-chlorophenyl)-[2-(1-methylpyrrolidin-2-yl)ethoxy]methyl]-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid
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C22H24ClN3O3
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1
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| 1 |
IC50 = 290 nM
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CP0546753
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US10022354, Example 47
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C21H24N6O
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1
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| 1 |
IC50 = 357 nM
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CP0396096
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2-[(2-chlorophenyl)-(3-piperidin-1-ylpropoxy)methyl]-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid
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C23H26ClN3O3
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1
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| 1 |
IC50 = 430 nM
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CP0558621
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US10022354, Example 46
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C21H26N6O
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1
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| 1 |
IC50 = 458 nM
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CP0517787
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US10022354, Example 71
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C22H25N5O
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1
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| 1 |
IC50 = 469 nM
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CP0164116
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CPI-455
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C16H14N4O
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1
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| 1 |
IC50 = 506 nM
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CP0396095
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2-[(S)-(2-chlorophenyl)-(2-piperidin-1-ylethoxy)methyl]-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid
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C22H24ClN3O3
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1
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| 1 |
IC50 = 590 nM
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CP0558581
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2-[(R)-(2-chlorophenyl)-(2-piperidin-1-ylethoxy)methyl]-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid
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C22H24ClN3O3
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1
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| 1 |
IC50 = 670 nM
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CP0556081
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2-[(2-chlorophenyl)-(2-piperidin-1-ylethoxy)methyl]-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid
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C22H24ClN3O3
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1
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| 1 |
IC50 = 690 nM
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CP0561227
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US10022354, Example 59
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C14H18BrN5O
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1
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| 1 |
IC50 = 727 nM
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CP0419828
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US10022354, Example 45
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C20H24N6O
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1
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| 1 |
IC50 = 878 nM
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CP0410700
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US10022354, Example 48
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C22H28N6O
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1
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| 1 |
IC50 = 897 nM
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CP0215948
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2-(5-phenyl-1H-pyrazol-1- yl)isonicotinic acid
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C15H11N3O2
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1
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| 1 |
IC50 = 1000 nM
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CP0393363
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2-(3-methyl-5-p-tolyl-1H-pyrazol- 1-yl)isonicotinic acid
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C17H15N3O2
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1
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| 1 |
IC50 = 1000 nM
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CP0393481
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2-(3-(2-chlorophenyl)-5-hydroxy- 1H-pyrazol-1-yl)isonicotinic acid
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C15H10ClN3O3
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1
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| 1 |
IC50 = 1000 nM
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CP0393484
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2-(5-methoxy-3-methyl-1H- pyrazol-1-yl)isonicotinic acid
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C11H11N3O3
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1
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| 1 |
IC50 = 1000 nM
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CP0457401
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2-(3-(2-fluorophenyl)-5-hydroxy- 1H-pyrazol-1-yl)isonicotinic acid
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C15H10FN3O3
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1
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| 1 |
IC50 = 1000 nM
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CP0458282
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2-[3-(3-chlorophenyl)-5- hydroxypyrazol-1-yl]pyridine-4- carboxylic acid
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C15H10ClN3O3
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1
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| 1 |
IC50 = 1000 nM
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CP0458283
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2-(3-benzyl-1H-pyrazol-1- yl)isonicotinic acid
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C16H13N3O2
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1
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| 1 |
IC50 = 1000 nM
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CP0476903
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2-(5-methyl-1H-pyrazol-1- yl)isonicotinic acid
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C10H9N3O2
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1
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| 1 |
IC50 = 1000 nM
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CP0490863
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2-(5-phenethyl-1H-pyrazol-1- yl)isonicotinic acid
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C17H15N3O2
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1
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| 1 |
IC50 = 1000 nM
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CP0490881
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2-(5-butyl-1H-pyrazol-1- yl)isonicotinic acid
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C13H15N3O2
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1
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| 1 |
IC50 = 1000 nM
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CP0513276
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2-(3-ethyl-5-p-tolyl-1H-pyrazol-1- yl)isonicotinic acid
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C18H17N3O2
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1
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| 1 |
IC50 = 1000 nM
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CP0530563
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2-(5-hydroxy-3-methyl-4- phenyl-1H-pyrazol-1- yl)isonicotinic acid
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C16H13N3O3
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1
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| 1 |
IC50 = 1000 nM
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CP0530575
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2-(3-cyclopentyl-5- hydroxypyrazol-1-yl)pyridine-4- carboxylic acid
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C14H15N3O3
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1
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| 1 |
IC50 = 1000 nM
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CP0530590
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2-[3-(4-chlorophenyl)-5- hydroxypyrazol-1-yl]pyridine-4- carboxylic acid
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C15H10ClN3O3
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1
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| 1 |
IC50 = 1000 nM
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CP0558732
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2-(5-hydroxy-3-(phenoxymethyl)- 1H-pyrazol-1-yl)isonicotinic acid
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C16H13N3O4
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1
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| 1 |
IC50 = 1000 nM
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CP0455741
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2-{1-[2-(morpholin-4-yl)ethyl]- 1H-imidazol-4-yl}pyridine-4- carboxylic acid
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C15H18N4O3
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1
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| 1 |
IC50 = 1000 nM
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CP0447048
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US10022354, Example 27
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C13H20N4O2
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1
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| 1 |
IC50 = 1100 nM
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CP0564232
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2-[(2-chlorophenyl)-[2-(1-methylimidazol-2-yl)ethoxy]methyl]-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid
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C21H19ClN4O3
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1
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| 1 |
IC50 = 1400 nM
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CP0558649
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US10022354, Example 54
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C19H25N5O2
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1
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| 1 |
IC50 = 1500 nM
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CP0390451
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[3-[6-methyl-4-(1-methylpyrazol-4-yl)pyridin-2-yl]pyrrolidin-1-yl]-(5-methyl-1H-pyrazol-3-yl)methanone
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C19H22N6O
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1
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| 1 |
IC50 = 2600 nM
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CP0045795
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3-[hydroxy-[5-[methyl(pentyl)amino]pentanoyl]amino]propanoic acid
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C14H28N2O4
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1
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| 1 |
IC50 = 2700 nM
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CP0558620
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[3-(dimethylamino)-1H-pyrazol-5-yl]-[3-[6-methyl-4-(1-methylpyrazol-4-yl)pyridin-2-yl]pyrrolidin-1-yl]methanone
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C20H25N7O
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1
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| 1 |
IC50 = 3300 nM
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CP0396097
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US10022354, Example 28
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C15H22N4O2
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1
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| 1 |
IC50 = 4300 nM
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CP0519324
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2-[(2-chlorophenyl)-[2-(4,4-difluoropiperidin-1-yl)ethoxy]methyl]-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid
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C22H22ClF2N3O3
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1
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| 1 |
IC50 = 4500 nM
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CP0958736
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2-((2-Chlorophenyl)(propoxy)methyl)-1H-pyrrolo[3,2-b]-pyridine-7-carboxylic Acid
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C18H17ClN2O3
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1
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| 1 |
IC50 = 6700 nM
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CP0543077
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US10022354, Example 5
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C20H27N5O2
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1
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| 1 |
IC50 = 7200 nM
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CP0566762
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US10022354, Example 36
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C16H21N5O
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1
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| 1 |
IC50 = 8900 nM
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CP0457402
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2-(5-benzyl-1H-pyrazol-1- yl)isonicotinic acid
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C16H13N3O2
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1
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| 1 |
IC50 > 10000 nM
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CP0561228
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US10022354, Example 52
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C16H20N4O2
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1
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| 1 |
IC50 = 14300 nM
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CP0558650
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US10022354, Example 58
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C17H24N6O2
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1
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| 1 |
IC50 = 14600 nM
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CP0556083
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2-[(2-chlorophenyl)-[(4,4-difluorocyclohexyl)methoxy]methyl]-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid
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C22H21ClF2N2O3
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1
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| 1 |
IC50 = 22000 nM
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CP0410696
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2-methyl-4-(1-methylpyrazol-4-yl)-6-[1-[(5-propan-2-yl-1H-pyrazol-3-yl)sulfonyl]pyrrolidin-3-yl]pyridine
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C20H26N6O2S
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1
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| 1 |
IC50 > 25000 nM
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CP0410697
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[3-[6-methyl-4-(1-methylpyrazol-4-yl)pyridin-2-yl]pyrrolidin-1-yl]-(2-propan-2-yl-1,3-thiazol-5-yl)methanone
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C21H25N5OS
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1
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| 1 |
IC50 > 25000 nM
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CP0410698
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[3-[6-methyl-4-(1-methylpyrazol-4-yl)pyridin-2-yl]pyrrolidin-1-yl]-(2-methyl-5-propan-2-ylpyrazol-3-yl)methanone
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C22H28N6O
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1
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| 1 |
IC50 > 25000 nM
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CP0414100
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[3-[3-methyl-5-(1-methylpyrazol-4-yl)phenyl]pyrrolidin-1-yl]-(5-propan-2-yl-1H-pyrazol-3-yl)methanone
Show/Hide
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C22H27N5O
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1
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| 1 |
IC50 > 25000 nM
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CP0414155
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US10022354, Example 108
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C21H24N6O
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1
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| 1 |
IC50 > 25000 nM
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CP0419827
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[3-[6-methyl-4-(1-methylpyrazol-4-yl)pyridin-2-yl]piperidin-1-yl]-(5-propan-2-yl-1H-pyrazol-3-yl)methanone
Show/Hide
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C22H28N6O
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1
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| 1 |
IC50 > 25000 nM
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CP0547954
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(3-morpholin-4-ylpyrrolidin-1-yl)-(5-propan-2-yl-1H-pyrazol-3-yl)methanone
Show/Hide
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C15H24N4O2
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1
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| 1 |
IC50 > 25000 nM
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CP0551661
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[4-[6-methyl-4-(1-methylpyrazol-4-yl)pyridin-2-yl]piperidin-1-yl]-(5-propan-2-yl-1H-pyrazol-3-yl)methanone
Show/Hide
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C22H28N6O
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1
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| 1 |
IC50 > 25000 nM
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CP0558619
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2-methyl-4-(1-methylpyrazol-4-yl)-6-[1-[(3-propan-2-yl-1H-pyrazol-5-yl)methyl]pyrrolidin-3-yl]pyridine
Show/Hide
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C21H28N6
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1
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| 1 |
IC50 > 25000 nM
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CP0563491
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1-[5-[3-[6-methyl-4-(1-methylpyrazol-4-yl)pyridin-2-yl]pyrrolidine-1-carbonyl]-1H-pyrazol-3-yl]ethanone
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C20H22N6O2
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1
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| 1 |
IC50 > 25000 nM
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CP0566759
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[3-[6-methyl-4-(1-methylpyrazol-4-yl)pyridin-2-yl]pyrrolidin-1-yl]-(3-propan-2-yl-1,2-oxazol-5-yl)methanone
Show/Hide
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C21H25N5O2
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1
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| 1 |
IC50 > 25000 nM
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CP0566760
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[3-[6-methyl-4-(1-methylpyrazol-4-yl)pyridin-2-yl]pyrrolidin-1-yl]-(5-propan-2-yl-1,2-oxazol-3-yl)methanone
Show/Hide
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C21H25N5O2
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1
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| 1 |
IC50 > 25000 nM
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CP0566761
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[3-[6-methyl-4-(1-methylpyrazol-4-yl)pyridin-2-yl]pyrrolidin-1-yl]-(1-methyl-5-propan-2-ylpyrazol-3-yl)methanone
Show/Hide
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C22H28N6O
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1
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| 1 |
IC50 > 25000 nM
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