Brief Information of the Cell Line and Protein
Cell Line ID: CL000994 , ROS 17/2.8
 Cell Line Info 
Synonyms
ROS 17/28
Ros 17/2.8
ROS-17/2.8
ROS17/28
ROS17/2.8
Category Cancer cell line
Organism
Rattus norvegicus (Rat)
Protein ID: PT02378 , Vitamin D3 receptor
 Protein Info 
Gene Name VDR
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P11473
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000994
 Cell Line Info 
 Protein ID: PT02378
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0003145
 Compound Info 
(1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
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C27H44O3
  1
1
ED50 = 1.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0426994
 Compound Info 
(1R,3S,Z)-5-((E)-2-((1R,3aS,7aR)-1-((S)-1-(3,3-dimethyl-2-methylenebutoxy)propan-2-yl)-7a-methyl-octahydroinden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol
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C29H46O3
  1
1
ED50 = 6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552250
 Compound Info 
(1R,3S,Z)-5-((E)-2-((1R,3aS,7aR)-1-((S)-1-(4,4-dimethylpent-2-ynyloxy)propan-2-yl)-7a-methyl-octahydroinden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol
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C29H44O3
  1
1
ED50 = 40 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0528403
 Compound Info 
(1R,3S,Z)-5-((E)-2-((1R,3aS,7aR)-1-((S)-1-(2-(6,6-dimethylcyclohex-1-enyl)allyloxy)propan-2-yl)-7a-methyl-octahydroinden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol
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C33H50O3
  1
1
ED50 = 52 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0523218
 Compound Info 
(1R,3S,Z)-5-((E)-2-((1R,3aS,7aR)-7a-methyl-1-((S)-1-(2-(1-methylcyclohexyl)allyloxy)propan-2-yl)-octahydroinden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol
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C32H50O3
  1
1
ED50 = 350 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0523217
 Compound Info 
(1R,3S,Z)-5-((E)-2-((1R,3aS,7aR)-1-((S)-1-(benzyloxy)propan-2-yl)-7a-methyl-octahydroinden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol
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C29H40O3
  1
1
ED50 = 410 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS