Brief Information of the Cell Line and Protein
Cell Line ID: CL000076 , CHO/Galpha16
 Cell Line Info 
Synonyms
CHO/Ga16
RD-HGA16
CHO-RD-HGA16
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_IY41
Protein ID: PT02346 , Prostaglandin E2 receptor EP4 subtype
 Protein Info 
Gene Name PTGER4
Organism Mus musculus, Mouse
Protein Classification Membrane receptor
Uniprot ID P32240
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000076
 Cell Line Info 
 Protein ID: PT02346
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0564321
 Compound Info 
4-[(1S)-1-[[2-[[3-(trifluoromethyl)phenyl]methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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C25H22F3NO4S
  1
1
IC50 = 2.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0576837
 Compound Info 
4-[(1S)-1-[[2-[2-(4-fluorophenyl)ethyl]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carbonyl]amino]ethyl]benzoic acid
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C25H24FNO3S
  1
1
IC50 = 19.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0569215
 Compound Info 
4-[[[2-[(4-fluorophenyl)methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]methyl]benzoic acid
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C23H20FNO4S
  1
1
IC50 = 24.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0564330
 Compound Info 
4-[(1S)-1-[[2-[2-(4-fluorophenyl)ethyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carbonyl]amino]ethyl]benzoic acid
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C26H26FNO3S
  1
1
IC50 = 29 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0569739
 Compound Info 
4-[(1S)-1-[[2-[2-(4-fluorophenyl)ethyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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C25H24FNO4S
  1
1
IC50 = 50.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0564380
 Compound Info 
4-[(1S)-1-[[2-[[4-(trifluoromethyl)phenyl]methylamino]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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C25H23F3N2O4S
  1
1
IC50 = 66.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0435681
 Compound Info 
US8686018, 107
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C22H18F5N3O4
  1
1
IC50 = 101.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0575940
 Compound Info 
4-[(1S)-1-[[2-[[4-(trifluoromethyl)phenyl]methyl]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbonyl]amino]ethyl]benzoic acid
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C25H22F3NO4S
  1
1
IC50 = 336.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS