Brief Information of the Cell Line and Protein
Cell Line ID: CL000026 , CHO-K1
Synonyms
CHO K1
CHOK1
CHO cell clone K1
GM15452
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0214
Protein ID: PT02259 , Neuropeptide Y receptor type 1
Gene Name NPY1R
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P25929
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000026  Protein ID: PT02259
 
Compound ID Compound Name Compound Formula
CP0504615
(S)-N-(4-(4-phenyl-5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C25H24N4S2
 1
1
Ki = 30 nM
   TI
   LI
   LO
   TS
CP0498901
(+/-)-N-(4-(4-methyl-5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C20H22N4S2
 1
1
Ki = 50 nM
   TI
   LI
   LO
   TS
CP0411175
(+/-)-N-(4-(4-isopropyl-5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C22H26N4S2
 1
1
Ki = 53 nM
   TI
   LI
   LO
   TS
CP0411179
(+/-)-N-(4-(4-phenyl-5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C25H24N4S2
 1
1
Ki = 55 nM
   TI
   LI
   LO
   TS
CP0507000
(+/-)-N-(4-(4-(4-methoxyphenyl)-5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C26H26N4OS2
 1
1
Ki = 55 nM
   TI
   LI
   LO
   TS
CP0510460
(+/-)-N-(4-(4-isobutyl-5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C23H28N4S2
 1
1
Ki = 62 nM
   TI
   LI
   LO
   TS
CP0518942
(+/-)-N-(4-(4-butyl-4,5-dihydrothiazol-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C22H26N4S2
 1
1
Ki = 69 nM
   TI
   LI
   LO
   TS
CP0522892
(+/-)-N-(4-(4-(3-chlorophenyl)-5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C25H23ClN4S2
 1
1
Ki = 107 nM
   TI
   LI
   LO
   TS
CP0518945
(+/-)-N-(4-(4-(4-chlorophenyl)-5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C25H23ClN4S2
 1
1
Ki = 122 nM
   TI
   LI
   LO
   TS
CP0504603
(R)-N-(4-(4-ethyl-4,5-dihydrothiazol-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C20H22N4S2
 1
1
Ki = 153 nM
   TI
   LI
   LO
   TS
CP0504608
(R)-N-(4-(4-phenyl-4,5-dihydrothiazol-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C24H22N4S2
 1
1
Ki = 175 nM
   TI
   LI
   LO
   TS
CP0497590
(+/-)-N-(4-(4-phenethyl-5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C27H28N4S2
 1
1
Ki = 195 nM
   TI
   LI
   LO
   TS
CP0407684
N-[2-[4-(5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenyl]ethyl]-1,3-benzothiazol-2-amine
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C19H20N4S2
 1
1
Ki = 221 nM
   TI
   LI
   LO
   TS
CP0411181
N-[2-[4-(4,5-dihydro-1,3-thiazol-2-ylamino)phenyl]ethyl]-1,3-benzothiazol-2-amine
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C18H18N4S2
 1
1
Ki = 248 nM
   TI
   LI
   LO
   TS
CP0518941
5,6-dichloro-N-(4-(5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C19H18Cl2N4S2
 1
1
Ki = 316 nM
   TI
   LI
   LO
   TS
CP0504600
N-[2-[4-(5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenyl]ethyl]-6-fluoro-1,3-benzothiazol-2-amine
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C19H19FN4S2
 1
1
Ki = 318 nM
   TI
   LI
   LO
   TS
CP0504613
(+/-)-N-(4-(4-cyclohexyl-5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C25H30N4S2
 1
1
Ki = 332 nM
   TI
   LI
   LO
   TS
CP0538526
6-chloro-N-(4-(5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C19H19ClN4S2
 1
1
Ki = 342 nM
   TI
   LI
   LO
   TS
CP0502459
(R)-N-(4-(4-methyl-4,5-dihydrothiazol-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C19H20N4S2
 1
1
Ki = 379 nM
   TI
   LI
   LO
   TS
CP0504616
(R)-N-(4-(4-phenyl-5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C25H24N4S2
 1
1
Ki = 464 nM
   TI
   LI
   LO
   TS
CP0504605
(+/-)-N-(4-(4-propyl-4,5-dihydrothiazol-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C21H24N4S2
 1
1
Ki = 482 nM
   TI
   LI
   LO
   TS
CP0482975
N-[2-[4-(5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenyl]ethyl]-6-methyl-1,3-benzothiazol-2-amine
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C20H22N4S2
 1
1
Ki = 616 nM
   TI
   LI
   LO
   TS
CP0504606
(R)-N-(4-(4-isobutyl-4,5-dihydrothiazol-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C22H26N4S2
 1
1
Ki = 712 nM
   TI
   LI
   LO
   TS
CP0411180
(+/-)-N-(4-(4-(2-chlorophenyl)-5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C25H23ClN4S2
 1
1
Ki = 956 nM
   TI
   LI
   LO
   TS
CP0518939
N-[2-[4-(4,5-dihydro-1,3-thiazol-2-ylamino)phenyl]ethyl]-6-methyl-1,3-benzothiazol-2-amine
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C19H20N4S2
 1
1
Ki = 1060 nM
   TI
   LI
   LO
   TS
CP0475777
N-[2-[4-(4,5-dihydro-1,3-thiazol-2-ylamino)phenyl]ethyl]-6-fluoro-1,3-benzothiazol-2-amine
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C18H17FN4S2
 1
1
Ki = 1120 nM
   TI
   LI
   LO
   TS
CP0469069
6-chloro-N-(4-(4,5-dihydrothiazol-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C18H17ClN4S2
 1
1
Ki = 1240 nM
   TI
   LI
   LO
   TS
CP0504599
N-[2-[4-(5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenyl]ethyl]-6-methoxy-1,3-benzothiazol-2-amine
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C20H22N4OS2
 1
1
Ki = 1250 nM
   TI
   LI
   LO
   TS
CP0504597
N-[2-[4-(4,5-dihydro-1,3-thiazol-2-ylamino)phenyl]ethyl]-6-methoxy-1,3-benzothiazol-2-amine
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C19H20N4OS2
 1
1
Ki = 1670 nM
   TI
   LI
   LO
   TS
CP0504610
N-[2-[4-[(5-methoxy-4,5-dihydro-1,3-thiazol-2-yl)amino]phenyl]ethyl]-1,3-benzothiazol-2-amine
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C19H20N4OS2
 1
1
Ki = 2550 nM
   TI
   LI
   LO
   TS
CP0504602
N-[2-[4-(5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenyl]ethyl]-6-nitro-1,3-benzothiazol-2-amine
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C19H19N5O2S2
 1
1
Ki = 3300 nM
   TI
   LI
   LO
   TS
CP0407682
N-[2-[4-(4,5-dihydro-1,3-thiazol-2-ylamino)phenyl]ethyl]-4-methyl-1,3-benzothiazol-2-amine
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C19H20N4S2
 1
1
Ki = 3460 nM
   TI
   LI
   LO
   TS
CP0538502
5,6-dichloro-N-(4-(4,5-dihydrothiazol-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
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C18H16Cl2N4S2
 1
1
Ki = 3640 nM
   TI
   LI
   LO
   TS
CP0498896
N-[2-[4-(4,5-dihydro-1,3-thiazol-2-ylamino)phenyl]ethyl]-4-methoxy-1,3-benzothiazol-2-amine
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C19H20N4OS2
 1
1
Ki = 3990 nM
   TI
   LI
   LO
   TS
CP0411173
N-[2-[4-(5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenyl]ethyl]-6-methylsulfonyl-1,3-benzothiazol-2-amine
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C20H22N4O2S3
 1
1
Ki = 5200 nM
   TI
   LI
   LO
   TS
CP0411172
N-[2-[4-(4,5-dihydro-1,3-thiazol-2-ylamino)phenyl]ethyl]-6-nitro-1,3-benzothiazol-2-amine
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C18H17N5O2S2
 1
1
Ki = 5250 nM
   TI
   LI
   LO
   TS
CP0498897
N-[2-[4-(4,5-dihydro-1,3-thiazol-2-ylamino)phenyl]ethyl]-6-methylsulfonyl-1,3-benzothiazol-2-amine
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C19H20N4O2S3
 1
1
Ki = 5920 nM
   TI
   LI
   LO
   TS