[2-(3-fluorophenyl)-5-methylsulfonylphenyl]-[2-(2-methylpyridin-4-yl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]methanone

[2-(3-fluorophenyl)-5-methylsulfonylphenyl]-[2-(5-fluoropyridin-3-yl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]methanone

[2-(4,4-difluoropiperidin-1-yl)-5-methylsulfonylphenyl]-[2-(2-methylpyridin-4-yl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]methanone

[2-(2-fluorophenyl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-[5-methylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]methanone

[2-(4,4-difluoropiperidin-1-yl)-5-methylsulfonylphenyl]-[2-(5-fluoropyridin-3-yl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]methanone

[2-(2-fluorophenyl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-[2-(3-fluorophenyl)-5-methylsulfonylphenyl]methanone

[2-(2-fluorophenyl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-[2-[(2-methylpropan-2-yl)oxy]-5-methylsulfonylphenyl]methanone

[2-(2-methylpyridin-4-yl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-[5-methylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]methanone

[5-ethylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]-[2-(2-methylpyridin-4-yl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]methanone

[5-methylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]-(2-phenyl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl)methanone

[3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]azetidin-1-yl]-[2-methoxy-3-methylsulfonyl-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]methanone

[2-(4,4-difluoropiperidin-1-yl)-5-methylsulfonylphenyl]-[2-(2-fluorophenyl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]methanone

(2-cyclopentyl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl)-[5-methylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]methanone

3-[2-(2-methylpyridin-4-yl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]-4-[(2S)-1,1,1-trifluoropropan-2-yl]oxybenzonitrile

[2-(5-fluoropyridin-2-yl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-[2-methoxy-3-methylsulfonyl-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]methanone

[4-[2-fluoro-4-(1-methoxyethyl)phenyl]piperazin-1-yl]-[2-(4-fluorophenyl)-5-methylsulfonylphenyl]methanone

4-(4,4-difluoropiperidin-1-yl)-3-[2-(2-methylpyridin-4-yl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]benzonitrile

3-[2-(2-methylpyridin-4-yl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]-4-propan-2-yloxybenzonitrile

3-[2-(5-fluoropyridin-2-yl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]-2-methoxy-4-[(2S)-1,1,1-trifluoropropan-2-yl]oxybenzonitrile

[2-(2-fluorophenyl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-(5-methylsulfonyl-2-propan-2-yloxyphenyl)methanone

[2-(5-fluoropyridin-3-yl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-[5-methylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]methanone

[2-(3-methylphenyl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-[5-methylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]methanone

[3-[3-fluoro-5-(trifluoromethyl)pyridin-2-yl]azetidin-1-yl]-[2-methoxy-3-methylsulfonyl-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]methanone

[5-ethylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]-[2-(5-fluoropyridin-3-yl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]methanone

[2-methoxy-3-methylsulfonyl-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]-[3-[4-(trifluoromethyl)phenyl]azetidin-1-yl]methanone

[5-ethylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]-[2-(2-fluorophenyl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]methanone

2-chloro-3-[2-(5-fluoropyridin-2-yl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]-4-[(2S)-1,1,1-trifluoropropan-2-yl]oxybenzonitrile

[2-(cyclopropylmethoxy)-5-methylsulfonylphenyl]-[2-(2-fluorophenyl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]methanone

[2-methoxy-3-methylsulfonyl-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]-[3-[5-(trifluoromethyl)pyridin-2-yl]azetidin-1-yl]methanone

4-(3-fluorophenyl)-3-[2-(2-methylpyridin-4-yl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]benzonitrile

N-cyclopentyl-N-[2-(3,5-difluoroanilino)-2-oxoethyl]-4-pyridin-2-ylbenzamide

N-cyclohexyl-N-[2-(3,5-difluoroanilino)-2-oxoethyl]-4-pyridin-2-ylbenzamide

3-[2-(5-fluoropyridin-3-yl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]-4-[(2S)-1,1,1-trifluoropropan-2-yl]oxybenzonitrile

3-[2-(2-fluorophenyl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]-4-[(2S)-1,1,1-trifluoropropan-2-yl]oxybenzonitrile

N-cyclohexyl-N-[2-(3,5-difluoroanilino)-2-oxoethyl]-4-pyrrolidin-1-ylbenzamide

N-[2-(3,5-difluoroanilino)-2-oxoethyl]-N-(oxan-3-yl)-4-pyridin-2-ylbenzamide

N-[(2R)-3-[(2S)-2-ethylpiperidin-1-yl]-2-hydroxypropyl]naphthalene-1-sulfonamide

N-[2-(3,5-difluoroanilino)-2-oxoethyl]-N-(2-methylpropyl)-4-pyridin-2-ylbenzamide

3-(2-phenyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl)-4-propan-2-yloxybenzonitrile

3-[2-(5-fluoropyridin-3-yl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]-4-propan-2-yloxybenzonitrile

N-(cyclobutylmethyl)-N-[2-(3,5-difluoroanilino)-2-oxoethyl]-4-pyridin-2-ylbenzamide

N-cyclohexyl-N-[2-(3,5-difluoroanilino)-2-oxoethyl]-6-pyrrolidin-1-ylpyridine-3-carboxamide

N-(cyclopropylmethyl)-N-[2-(3,5-difluoroanilino)-2-oxoethyl]-4-pyridin-2-ylbenzamide

3-(2-cyclopentyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl)-4-[(2S)-1,1,1-trifluoropropan-2-yl]oxybenzonitrile

[2-methoxy-3-methylsulfonyl-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]-(3-phenylazetidin-1-yl)methanone

N-[(2R)-2-hydroxy-3-(2-methylpiperidin-1-yl)propyl]naphthalene-1-sulfonamide

4-(3-fluorophenyl)-3-[2-(5-fluoropyridin-3-yl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]benzonitrile

N-cyclohexyl-4-methoxy-N-[(5-phenyl-1,2-oxazol-3-yl)methyl]benzamide

N-butan-2-yl-N-[2-(3,5-difluoroanilino)-2-oxoethyl]-4-pyridin-2-ylbenzamide

(2-phenyl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl)-[5-propan-2-ylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]methanone

4-(cyclopropylmethoxy)-3-[2-(2-methylpyridin-4-yl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]benzonitrile

N-cyclohexyl-N-[2-(3,5-difluoroanilino)-2-oxoethyl]-4-methoxybenzamide

[5-methylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]-[3-[4-(trifluoromethyl)phenyl]azetidin-1-yl]methanone

N-cyclohexyl-N-[2-(3,5-difluoroanilino)-2-oxoethyl]-4-imidazol-1-ylbenzamide

4-chloro-N-cyclohexyl-N-[2-(3,5-difluoroanilino)-2-oxoethyl]benzamide

N-[(2R)-3-(2,5-dimethylpyrrolidin-1-yl)-2-hydroxypropyl]naphthalene-1-sulfonamide

N-[(2R)-2-hydroxy-3-(2-methylpyrrolidin-1-yl)propyl]naphthalene-1-sulfonamide

N-[(2R)-3-[tert-butyl(propyl)amino]-2-hydroxypropyl]naphthalene-1-sulfonamide

N-[(2R)-3-(5-ethyl-2-methylpiperidin-1-yl)-2-hydroxypropyl]naphthalene-1-sulfonamide

N-[2-(3,5-difluoroanilino)-2-oxoethyl]-N-(oxan-4-yl)-4-pyridin-2-ylbenzamide

N-[2-(3,5-difluoroanilino)-2-oxoethyl]-N-(2-methoxyethyl)-4-pyridin-2-ylbenzamide

N-[(2R)-3-[butan-2-yl(propyl)amino]-2-hydroxypropyl]naphthalene-1-sulfonamide

N-[2-(3,5-difluoroanilino)-2-oxoethyl]-N-(oxolan-3-yl)-4-pyridin-2-ylbenzamide

N-[2-(3,5-difluoroanilino)-2-oxoethyl]-N-(1-methoxybutan-2-yl)-4-pyridin-2-ylbenzamide

N-[2-(3,5-difluoroanilino)-2-oxoethyl]-N-(1-methoxypropan-2-yl)-4-pyridin-2-ylbenzamide

N-[2-(3,5-difluoroanilino)-2-oxoethyl]-N-propan-2-yl-4-pyridin-2-ylbenzamide

N-[[5-(4-chlorophenyl)furan-2-yl]methyl]-N-cyclohexyl-4-methoxybenzamide

3-chloro-N-cyclohexyl-N-[2-(3,5-difluoroanilino)-2-oxoethyl]benzamide

2,3-dichloro-N-[(2R)-3-(2,4-dimethylpyrrolidin-1-yl)-2-hydroxypropyl]benzenesulfonamide

N-cyclohexyl-4-methoxy-N-[(1-phenyltriazol-4-yl)methyl]benzamide

2-[(4-chlorophenyl)carbamoyl-cyclohexylamino]-N-(3,5-difluorophenyl)acetamide

2,5-dichloro-N-[(2R)-3-(2,4-dimethylpyrrolidin-1-yl)-2-hydroxypropyl]thiophene-3-sulfonamide

4-bromo-N-[(2R)-3-(2,4-dimethylpyrrolidin-1-yl)-2-hydroxypropyl]-2-ethylbenzenesulfonamide

N-[(2R)-2-hydroxy-3-pyrrolidin-1-ylpropyl]naphthalene-1-sulfonamide

4-chloro-N-[(2R)-3-(2,4-dimethylpyrrolidin-1-yl)-2-hydroxypropyl]-2,5-dimethylbenzenesulfonamide

N-[(2R)-2-hydroxy-3-piperidin-1-ylpropyl]naphthalene-1-sulfonamide

4-chloro-N-[2-(3,5-difluoroanilino)-2-oxoethyl]-N-(2-methylpropyl)benzamide

N-[(2R)-3-(2,4-dimethylpyrrolidin-1-yl)-2-hydroxypropyl]naphthalene-2-sulfonamide

N-[(2R)-2-hydroxy-3-(3-methylpiperidin-1-yl)propyl]naphthalene-1-sulfonamide

4-chloro-N-cyclohexyl-N-[1-(3,5-difluoroanilino)-1-oxopropan-2-yl]benzamide

N-cyclohexyl-N-[2-(3,5-difluoroanilino)-2-oxoethyl]oxane-4-carboxamide

N-[(2R)-3-(2-cyclohexylpyrrolidin-1-yl)-2-hydroxypropyl]naphthalene-1-sulfonamide

N-cyclohexyl-N-[2-(3,5-difluoroanilino)-2-oxoethyl]cyclohexanecarboxamide

N-[(2R)-3-(2-ethylpiperidin-1-yl)-2-hydroxypropyl]naphthalene-1-sulfonamide

N-[(2S)-3-(2,5-dimethylpyrrolidin-1-yl)-2-hydroxypropyl]naphthalene-1-sulfonamide

N-cyclohexyl-4-methoxy-N-[(2-phenyl-1,3-thiazol-4-yl)methyl]benzamide

4-chloro-N-cyclohexyl-N-[3-(3,5-difluoroanilino)-3-oxopropyl]benzamide

[4-(4-amino-2-fluorophenyl)piperazin-1-yl]-[2-(4-fluorophenyl)-5-methylsulfonylphenyl]methanone

N-[(2S)-2-hydroxy-3-(2-methylpyrrolidin-1-yl)propyl]naphthalene-1-sulfonamide

2-[(4-chlorophenyl)sulfonyl-cyclohexylamino]-N-(3,5-difluorophenyl)acetamide

N-cyclohexyl-4-methoxy-N-[(3-methyl-5-phenyl-1,2-oxazol-4-yl)methyl]benzamide

N-cyclohexyl-4-methoxy-N-[(2-phenyl-1H-imidazol-5-yl)methyl]benzamide

N-cyclohexyl-N-[2-(3,5-difluoroanilino)-2-oxoethyl]-4-[2-(dimethylamino)ethoxy]benzamide

2-chloro-N-cyclohexyl-N-[2-(3,5-difluoroanilino)-2-oxoethyl]benzamide

N-cyclohexyl-N-[2-(3,5-difluoroanilino)-2-oxoethyl]-1-methylpyrazole-3-carboxamide

2-[(4-chlorophenyl)methyl-cyclohexylamino]-N-(3,5-difluorophenyl)acetamide

N-cyclohexyl-N-[2-(3,5-difluoroanilino)-2-oxoethyl]pyridine-3-carboxamide

N-cyclohexyl-4-methoxy-N-[(4-phenyl-1H-pyrazol-5-yl)methyl]benzamide

N-cyclohexyl-N-[2-(3,5-difluoroanilino)-2-oxoethyl]-1-methylpiperidine-4-carboxamide

(exo)-1-Methyl-1H-imidazole-4-carboxylic acid(3-trifluoromethyl, 4-fluorobenzyl)-(octahydro-cyclopenta[c]pyrrol-5-yl)-amide

N-((cis)-4-aminocyclohexyl)-N-(3-chlorobenzyl)-1-methyl-1H-imidazole-4-carboxamide dihydrochloride

(exo)-1-methyl-N-(octahydrocyclopenta[c]pyrrol-5-yl)-N-(3-(trifluoromethoxy)benzyl)-1H-imidazole-4-carboxamide

(exo)-1-Methyl-1H-imidazole-4-carboxylic acid(3-cyclopentyloxy, 4-fluorobenzyl)-octahydro-cyclopenta[c]pyrrol-5-yl)-amide

(exo)-1-methyl-N-(2-methyloctahydrocyclopenta[c]pyrrol-5-yl)-N-(3-(trifluoromethoxy)benzyl)-1H-imidazole-4-carboxamide

(exo)-N-(2-ethyloctahydrocyclopenta[c]pyrrol-5-yl)-N-(4-fluoro-3-(trifluoromethyl)benzyl)-1-methyl-1H-imidazole-4-carboxamide

(exo)-N-(2-(2-hydroxy-2-phenylethyl)octahydrocyclopenta[c]pyrrol-5-yl)-1-methyl-N-(3-(trifluoromethoxy)benzyl)-1H-imidazole-4-carboxamide

(exo)-1-Methyl-1H-imidazole-4-carboxylic acid(3-trifluoromethyl, 4-fluorobenzyl)-(2-methyl-octahydro-cyclopenta[c]pyrrol-5-yl)-amide

(exo)-1-Methyl-1H-imidazole-4-carboxylic acid(3-cyclopentyloxy-4-fluorobenzyl)-(2-methyl-octahydro-cyclopenta[c]pyrrol-5-yl)-amide

(exo)-N-(2-ethyloctahydrocyclopenta[c]pyrrol-5-yl)-1-methyl-N-(3-(trifluoromethoxy)benzyl)-1H-imidazole-4-carboxamide

(exo)-N-(3-isopropoxybenzyl)-1-methyl-N-(octahydrocyclopenta[c]pyrrol-5-yl)-1H-imidazole-4-carboxamide

(exo)-N-(2-(2-fluoropropyl)octahydrocyclopenta[c]pyrrol-5-yl)-1-methyl-N-(3-(trifluoromethoxy)benzyl)-1H-imidazole-4-carboxamide

(exo)-N-(3-(cyclopentyloxy)benzyl)-1-methyl-N-(octahydrocyclopenta[c]pyrrol-5-yl)-1H-imidazole-4-carboxamide

(exo)-1-Methyl-1H-imidazole-4-carboxylic acid(3-trifluoromethoxy-benzyl)-(2-(2-hydroxy, 2-methylpropyl)-octahydro-cyclopenta[c]pyrrol-5-yl)-amide

(1-(3-(7-((5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)methoxy)-1,2,3,4-tetrahydronaphthalen-1-yl)propyl)piperidin-3-yl)methanol

(exo)-1-methyl-N-(3-(trifluoromethoxy)benzyl)-N-(2-(3,3,3-trifluoropropyl)octahydrocyclopenta[c]pyrrol-5-yl)-1H-imidazole-4-carboxamide

(1-(3-(7-((5-(2-fluorophenyl)pyridin-2-yl)methoxy)-1,2,3,4-tetrahydronaphthalen-1-yl)propyl)piperidin-3-yl)methanol

(1-(3-(7-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)methoxy)-1,2,3,4-tetrahydronaphthalen-1-yl)propyl)piperidin-3-yl)methanol

(1-(4-(6-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)methoxy)-2,3-dihydro-1H-inden-1-yl)piperazin-1-yl)cyclopentyl)methanol

(endo)-N-(4-fluoro-3-(trifluoromethyl)benzyl)-1-methyl-N-(octahydrocyclopenta[c]pyrrol-5-yl)-1H-imidazole-4-carboxamide

(1-(4-(6-((5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)methoxy)-2,3-dihydro-1H-inden-1-yl)piperazin-1-yl)cyclopentyl)methanol

1-cyclopentyl-4-(6-((5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)methoxy)-2,3-dihydro-1H-inden-1-yl)piperazine

1-(3,4-dimethylcyclopentyl)-N-ethyl-N-[[3-[[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]methoxy]phenyl]methyl]pyrrolidin-3-amine

(1-(3-(6-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)methoxy)-2,3-dihydro-1H-inden-1-yl)propylamino)cyclopentyl)methanol

1-(6-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)methoxy)-2,3-dihydro-1H-inden-1-yl)-4-(3,4-dimethylcyclopentyl)piperazine

1-(6-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)methoxy)-2,3-dihydro-1H-inden-1-yl)-4-isopropylpiperazine

1-(7-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)methoxy)naphthalen-1-yl)-4-methylpiperazine

(exo)-N-(3-(cyclopentyloxy)-4-methoxybenzyl)-1-methyl-N-(octahydrocyclopenta[c]pyrrol-5-yl)-1H-imidazole-4-carboxamide