Brief Information of the Cell Line and Protein
Cell Line ID: CL000670 , CF2.Th
Synonyms
Cf2Th
CF2Th
CF2TH
Cf2TH
FCf2Th
Category Spontaneously immortalized cell line
Organism
Canis lupus familiaris (Dog)
Cellosaurus ID
CVCL_3363
Protein ID: PT02059 , C-X-C chemokine receptor type 4
Gene Name CXCR4
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P61073
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000670  Protein ID: PT02059
 
Compound ID Compound Name Compound Formula
CP0415026
1-[3-[[amino-(naphthalen-1-ylamino)methylidene]amino]propyl]-1-[4-[3-[[amino-(naphthalen-1-ylamino)methylidene]amino]propylamino]butyl]-2-naphthalen-1-ylguanidine
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C43H50N10
 1
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
CP0499174
2-[3-[4-[[amino-(naphthalen-2-ylamino)methylidene]amino]butylamino]propyl]-1-naphthalen-2-ylguanidine
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C29H35N7
 1
1
IC50 = 62 nM
   TI
   LI
   LO
   TS
CP0474060
1-[3-[[amino-(naphthalen-2-ylamino)methylidene]amino]propyl]-1-[4-[3-[[amino-(naphthalen-2-ylamino)methylidene]amino]propylamino]butyl]-2-naphthalen-2-ylguanidine
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C43H50N10
 1
1
IC50 = 93 nM
   TI
   LI
   LO
   TS
CP0422525
2-[3-[4-[3-[[amino-(naphthalen-2-ylamino)methylidene]amino]propylamino]butylamino]propyl]-1-naphthalen-2-ylguanidine
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C32H42N8
 1
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
CP0452374
1-[4-[[amino-(naphthalen-1-ylamino)methylidene]amino]butyl]-1-[3-[[amino-(naphthalen-1-ylamino)methylidene]amino]propyl]-2-naphthalen-1-ylguanidine
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C40H43N9
 1
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
CP0422526
2-[3-[4-[3-[[amino-(naphthalen-1-ylamino)methylidene]amino]propylamino]butylamino]propyl]-1-naphthalen-1-ylguanidine
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C32H42N8
 1
1
IC50 = 180 nM
   TI
   LI
   LO
   TS
CP0446992
1-[4-[[amino-(naphthalen-2-ylamino)methylidene]amino]butyl]-1-[3-[[amino-(naphthalen-2-ylamino)methylidene]amino]propyl]-2-naphthalen-2-ylguanidine
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C40H43N9
 1
1
IC50 = 190 nM
   TI
   LI
   LO
   TS
CP0511504
2-[3-[4-[[amino-(naphthalen-1-ylamino)methylidene]amino]butylamino]propyl]-1-naphthalen-1-ylguanidine
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C29H35N7
 1
1
IC50 = 220 nM
   TI
   LI
   LO
   TS
CP0452377
2-[3-[4-[[amino(anilino)methylidene]amino]butylamino]propyl]-1-phenylguanidine
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C21H31N7
 1
1
IC50 = 260 nM
   TI
   LI
   LO
   TS
CP0452376
1-[4-[[amino(anilino)methylidene]amino]butyl]-1-[3-[[amino(anilino)methylidene]amino]propyl]-2-phenylguanidine
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C28H37N9
 1
1
IC50 = 280 nM
   TI
   LI
   LO
   TS
CP0473372
1-[3-[[amino-(naphthalen-2-ylamino)methylidene]amino]propyl]-1-[4-[3-[[amino-(naphthalen-2-ylamino)methylidene]amino]propyl-(N'-naphthalen-2-ylcarbamimidoyl)amino]butyl]-2-naphthalen-2-ylguanidine
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C54H58N12
 1
1
IC50 = 300 nM
   TI
   LI
   LO
   TS
CP0483772
1-[3-[[amino-(naphthalen-1-ylamino)methylidene]amino]propyl]-1-[4-[3-[[amino-(naphthalen-1-ylamino)methylidene]amino]propyl-(N'-naphthalen-1-ylcarbamimidoyl)amino]butyl]-2-naphthalen-1-ylguanidine
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C54H58N12
 1
1
IC50 = 380 nM
   TI
   LI
   LO
   TS
CP0452375
1-[3-[[amino(anilino)methylidene]amino]propyl]-1-[4-[3-[[amino(anilino)methylidene]amino]propyl-(N'-phenylcarbamimidoyl)amino]butyl]-2-phenylguanidine
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C38H50N12
 1
1
IC50 = 510 nM
   TI
   LI
   LO
   TS