Brief Information of the Cell Line and Protein
Cell Line ID: CL000035 , NIH 3T3
Synonyms
NIH/3T3
NIH-3T3
NIH3T3
3T3
3T3NIH
3T3-Swiss
Swiss-3T3
Swiss/3T3
Swiss 3T3
Swiss3T3
Category Spontaneously immortalized cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0594
Protein ID: PT01823 , Prostaglandin F2-alpha receptor
Gene Name PTGFR
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P43088
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000035  Protein ID: PT01823
 
Compound ID Compound Name Compound Formula
CP0264733
(E)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-3-hydroxy-4-(3-trifluoromethyl-phenoxy)-but-1-enyl]-cyclopentyl}-hept-5-enoic acid isopropyl ester
   Show/Hide
C26H35F3O6
 1
1
EC50 = 2.7 nM
   TI
   LI
   LO
   TS
CP0272645
(Z)-8-{(2R,3S,4R)-2-[(E)-(R)-4-(3-Chloro-phenoxy)-3-hydroxy-but-1-enyl]-4-hydroxy-tetrahydro-furan-3-yl}-oct-4-enoic acid
   Show/Hide
C22H29ClO6
 1
1
EC50 = 23 nM
   TI
   LI
   LO
   TS
CP0095751
(5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dien-1-oic acid
   Show/Hide
C20H34O5
 1
1
EC50 = 24.5 nM
   TI
   LI
   LO
   TS
CP0316561
(E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-5-phenyl-pentyl)-cyclopentyl]-hept-5-enoic acid isopropyl ester
   Show/Hide
C26H40O5
 1
1
EC50 = 34.4 nM
   TI
   LI
   LO
   TS
CP0151350
(Z)-8-[(2R,3S,4R)-4-Hydroxy-2-((E)-(R)-3-hydroxy-4-phenoxy-but-1-enyl)-tetrahydro-furan-3-yl]-oct-4-enoic acid
   Show/Hide
C22H30O6
 1
1
EC50 = 57 nM
   TI
   LI
   LO
   TS
CP0285700
(Z)-8-{(2R,3S,4R)-2-[(E)-(R)-4-(3-Chloro-phenoxy)-3-hydroxy-but-1-enyl]-4-hydroxy-tetrahydro-furan-3-yl}-oct-6-enoic acid
   Show/Hide
C22H29ClO6
 1
1
EC50 = 58 nM
   TI
   LI
   LO
   TS
CP0050513
(Z)-8-{(2R,3S,4R)-4-Hydroxy-2-[(E)-(R)-3-hydroxy-4-(3-trifluoromethyl-phenoxy)-but-1-enyl]-tetrahydro-furan-3-yl}-oct-4-enoic acid
   Show/Hide
C23H29F3O6
 1
1
EC50 = 67 nM
   TI
   LI
   LO
   TS
CP0333250
(Z)-8-{(2R,3S,4R)-4-Hydroxy-2-[(E)-(R)-3-hydroxy-4-(3-trifluoromethyl-phenoxy)-but-1-enyl]-tetrahydro-furan-3-yl}-oct-6-enoic acid
   Show/Hide
C23H29F3O6
 1
1
EC50 = 187 nM
   TI
   LI
   LO
   TS
CP0306961
(Z)-8-{(2R,3S,4R)-2-[(E)-(S)-4-(3-Chloro-phenoxy)-3-hydroxy-but-1-enyl]-4-hydroxy-tetrahydro-furan-3-yl}-oct-6-enoic acid
   Show/Hide
C22H29ClO6
 1
1
EC50 = 194 nM
   TI
   LI
   LO
   TS
CP0333251
(Z)-8-{(2R,3S,4R)-2-[(E)-(S)-4-(3-Chloro-phenoxy)-3-hydroxy-but-1-enyl]-4-hydroxy-tetrahydro-furan-3-yl}-oct-4-enoic acid
   Show/Hide
C22H29ClO6
 1
1
EC50 = 249 nM
   TI
   LI
   LO
   TS
CP0151351
(Z)-8-[(2R,3S,4R)-4-Hydroxy-2-((E)-(S)-3-hydroxy-4-phenoxy-but-1-enyl)-tetrahydro-furan-3-yl]-oct-4-enoic acid
   Show/Hide
C22H30O6
 1
1
EC50 = 252 nM
   TI
   LI
   LO
   TS
CP0282210
(Z)-8-[(2R,3S,4R)-4-Hydroxy-2-((E)-(R)-3-hydroxy-4-phenoxy-but-1-enyl)-tetrahydro-furan-3-yl]-oct-6-enoic acid
   Show/Hide
C22H30O6
 1
1
EC50 = 293 nM
   TI
   LI
   LO
   TS
CP0278130
(Z)-8-[(R)-4-Hydroxy-2-((1R,2S,4S)-3-hydroxy-4-phenoxy-but-1-enyl)-tetrahydro-furan-3-yl]-oct-6-enoic acid
   Show/Hide
C22H30O6
 1
1
EC50 = 573 nM
   TI
   LI
   LO
   TS
CP0280807
(Z)-8-{(2R,3S,4R)-4-Hydroxy-2-[(E)-(S)-3-hydroxy-4-(3-trifluoromethyl-phenoxy)-but-1-enyl]-tetrahydro-furan-3-yl}-oct-4-enoic acid
   Show/Hide
C23H29F3O6
 1
1
EC50 = 781 nM
   TI
   LI
   LO
   TS
CP0283804
(Z)-8-{(2R,3S,4R)-4-Hydroxy-2-[(E)-(S)-3-hydroxy-4-(3-trifluoromethyl-phenoxy)-but-1-enyl]-tetrahydro-furan-3-yl}-oct-6-enoic acid
   Show/Hide
C23H29F3O6
 1
1
EC50 = 899 nM
   TI
   LI
   LO
   TS
CP0180296
(Z)-7-[(2R,3S,4R)-4-Hydroxy-2-((E)-(S)-3-hydroxy-oct-1-enyl)-tetrahydro-furan-3-yl]-hept-5-enoic acid
   Show/Hide
C19H32O5
 1
1
EC50 = 2380 nM
   TI
   LI
   LO
   TS
CP0078411
(Z)-7-[(2R,3S,4R)-4-Hydroxy-2-((E)-(R)-3-hydroxy-oct-1-enyl)-tetrahydro-furan-3-yl]-hept-5-enoic acid
   Show/Hide
C19H32O5
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS