Brief Information of the Cell Line and Protein
Cell Line ID: CL000026 , CHO-K1
Synonyms
CHO K1
CHOK1
CHO cell clone K1
GM15452
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0214
Protein ID: PT01823 , Prostaglandin F2-alpha receptor
Gene Name PTGFR
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P43088
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000026  Protein ID: PT01823
 
Compound ID Compound Name Compound Formula
CP0295469
(Z)-7-{(1R,2R,3R,5S)-2-[(E)-(R)-4-(3-Chloro-phenoxy)-3-hydroxy-but-1-enyl]-3,5-dihydroxy-cyclopentyl}-hept-5-enoic acid
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C22H29ClO6
 1
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
CP0402541
7-{(1R,2R,3R,5S)-2-[(R)-4-(3-Chloro-phenoxy)-3-hydroxy-butyl]-3,5-dihydroxy-cyclopentyl}-heptanoic acid
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C22H33ClO6
 1
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
CP0095751
(5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dien-1-oic acid
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C20H34O5
 1
1
IC50 = 2.5 nM
   TI
   LI
   LO
   TS
CP0404058
7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-(3-trifluoromethyl-phenyl)-pentyl]-cyclopentyl}-heptanoic acid
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C24H35F3O5
 1
1
IC50 = 8.6 nM
   TI
   LI
   LO
   TS
CP0528790
(Z)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-(S)-3-hydroxy-5-(3-trifluoromethyl-phenyl)-pent-1-enyl]-cyclopentyl}-hept-5-enoic acid
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C24H31F3O5
 1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
CP0405571
(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-(R)-3-hydroxy-4,4-dimethyl-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid
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C22H38O5
 1
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
CP0453409
7-{(1R,2R,3R,5S)-2-[(R)-5-(3-Fluoro-phenyl)-3-hydroxy-pentyl]-3,5-dihydroxy-cyclopentyl}-heptanoic acid
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C23H35FO5
 1
1
IC50 = 42 nM
   TI
   LI
   LO
   TS
CP0449088
7-{(1R,2R,3R,5S)-2-[(R)-5-(2-Fluoro-phenyl)-3-hydroxy-pentyl]-3,5-dihydroxy-cyclopentyl}-heptanoic acid
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C23H35FO5
 1
1
IC50 = 76 nM
   TI
   LI
   LO
   TS
CP0402565
7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-5-phenyl-pentyl)-cyclopentyl]-heptanoic acid
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C23H36O5
 1
1
IC50 = 82 nM
   TI
   LI
   LO
   TS
CP0425924
7-{(1R,2R,3R,5S)-2-[(R)-5-(3-Cyano-phenyl)-3-hydroxy-pentyl]-3,5-dihydroxy-cyclopentyl}-heptanoic acid
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C24H35NO5
 1
1
IC50 = 210 nM
   TI
   LI
   LO
   TS
CP0466595
7-{(1R,2R,3R,5S)-2-[(R)-5-(4-Fluoro-phenyl)-3-hydroxy-pentyl]-3,5-dihydroxy-cyclopentyl}-heptanoic acid
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C23H35FO5
 1
1
IC50 = 210 nM
   TI
   LI
   LO
   TS
CP0457103
7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-(4-methoxy-phenyl)-pentyl]-cyclopentyl}-heptanoic acid
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C24H38O6
 1
1
IC50 = 290 nM
   TI
   LI
   LO
   TS
CP0432809
7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((S)-3-hydroxy-octyl)-cyclopentyl]-heptanoic acid
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C20H38O5
 1
1
IC50 = 522 nM
   TI
   LI
   LO
   TS
CP0428991
7-{(1R,2R,3R,5S)-2-[(R)-5-(3-Ethyl-phenyl)-3-hydroxy-pentyl]-3,5-dihydroxy-cyclopentyl}-heptanoic acid
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C25H40O5
 1
1
IC50 = 540 nM
   TI
   LI
   LO
   TS
CP0453390
7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-5-o-tolyl-pentyl)-cyclopentyl]-heptanoic acid
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C24H38O5
 1
1
IC50 = 630 nM
   TI
   LI
   LO
   TS
CP0456706
7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-(3-methoxy-phenyl)-pentyl]-cyclopentyl}-heptanoic acid
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C24H38O6
 1
1
IC50 = 1620 nM
   TI
   LI
   LO
   TS
CP0456818
7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-(2-trifluoromethyl-phenyl)-pentyl]-cyclopentyl}-heptanoic acid
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C24H35F3O5
 1
1
IC50 = 2140 nM
   TI
   LI
   LO
   TS
CP0372234
7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-(4-trifluoromethyl-phenyl)-pentyl]-cyclopentyl}-heptanoic acid
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C24H35F3O5
 1
1
IC50 = 3630 nM
   TI
   LI
   LO
   TS
CP0404150
7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-5-p-tolyl-pentyl)-cyclopentyl]-heptanoic acid
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C24H38O5
 1
1
IC50 = 4400 nM
   TI
   LI
   LO
   TS
CP0375810
7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-(2-methoxy-phenyl)-pentyl]-cyclopentyl}-heptanoic acid
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C24H38O6
 1
1
IC50 = 5890 nM
   TI
   LI
   LO
   TS
CP0497580
7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-4,4-dimethyl-octyl)-cyclopentyl]-heptanoic acid
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C22H42O5
 1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS