3-(2,2-difluoro-10,12-dimethyl-1-aza-3-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-3,5,7,9,11-pentaen-4-yl)-N-[2-[2-[2-[2-[[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl]amino]ethoxy]ethoxy]ethoxy]ethyl]propanamide

3-(2,2-difluoro-10,12-dimethyl-1-aza-3-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-3,5,7,9,11-pentaen-4-yl)-N-[2-[2-[2-[2-[[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl]-methylamino]ethoxy]ethoxy]ethoxy]ethyl]propanamide

3-N-(2,6-dimethylphenyl)-1-(3-methoxy-3-methylbutyl)-6-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrazolo[3,4-d]pyrimidine-3,6-diamine

3-N-(2,6-dimethylphenyl)-1-(3-methoxy-3-methylbutyl)-6-N-(4-piperazin-1-ylphenyl)pyrazolo[3,4-d]pyrimidine-3,6-diamine

3-N-(2,6-dichlorophenyl)-6-N-[3-fluoro-4-(2-pyrrolidin-1-ylethoxy)phenyl]-1-(3-methoxy-3-methylbutyl)pyrazolo[3,4-d]pyrimidine-3,6-diamine

3-N-(2,6-dimethylphenyl)-6-N-[3-fluoro-4-(2-pyrrolidin-1-ylethoxy)phenyl]-1-(3-methoxy-3-methylbutyl)pyrazolo[3,4-d]pyrimidine-3,6-diamine

3-N-(2,6-dimethylphenyl)-1-(3-methoxy-3-methylbutyl)-6-N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]pyrazolo[3,4-d]pyrimidine-3,6-diamine

3-N-(2,6-dimethylphenyl)-1-(3-methoxy-3-methylbutyl)-6-N-phenylpyrazolo[3,4-d]pyrimidine-3,6-diamine

3-N-(2,6-dimethylphenyl)-6-N-[3-fluoro-4-(3-piperidin-1-ylpropoxy)phenyl]-1-(3-methoxy-3-methylbutyl)pyrazolo[3,4-d]pyrimidine-3,6-diamine

3-N-(2,6-dichlorophenyl)-1-[2-(dimethylamino)ethyl]-6-N-phenylpyrazolo[3,4-d]pyrimidine-3,6-diamine

3-N-(2,6-dichlorophenyl)-1-[3-(dimethylamino)propyl]-6-N-phenylpyrazolo[3,4-d]pyrimidine-3,6-diamine

3-N-(2,6-dichlorophenyl)-1-(3-methoxy-3-methylbutyl)-6-N-phenylpyrazolo[3,4-d]pyrimidine-3,6-diamine

(R)-N3-(2,6-dichlorophenyl)-1-(2-(3-(dimethylamino)pyrrolidin-1-yl)ethyl)-N6-phenyl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine

(R)-4-(3-(2,6-dichlorophenylamino)-6-(phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)butane-1,2-diol

3-N-(2,6-dichlorophenyl)-1-[2-(4-methylpiperazin-1-yl)ethyl]-6-N-phenylpyrazolo[3,4-d]pyrimidine-3,6-diamine

1-(3-methoxy-3-methylbutyl)-6-N-[4-(4-methylpiperazin-1-yl)phenyl]-3-N-(2,4,6-trimethylphenyl)pyrazolo[3,4-d]pyrimidine-3,6-diamine

3-N-(2,6-dichlorophenyl)-1-(3-methoxy-3-methylbutyl)-6-N-(4-piperazin-1-ylphenyl)pyrazolo[3,4-d]pyrimidine-3,6-diamine

3-N-(4-fluoro-2,6-dimethylphenyl)-1-(3-methoxy-3-methylbutyl)-6-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrazolo[3,4-d]pyrimidine-3,6-diamine

N-(2,6-dimethylphenyl)-4-(2-ethoxyphenoxy)-2-(4-piperazin-1-ylanilino)pyrimidine-5-carboxamide

3-N-(4-fluoro-2,6-dimethylphenyl)-1-(3-methoxy-3-methylbutyl)-6-N-phenylpyrazolo[3,4-d]pyrimidine-3,6-diamine

(R)-4-(3-(2,6-dimethylphenylamino)-6-(phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)butane-1,2-diol

1-(3-(dimethylamino)propyl)-N3-(2,6-dimethylphenyl)-N6-phenyl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine

(R)-(1-(2-(3-(2,6-dichlorophenylamino)-6-(phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)pyrrolidin-2-yl)methanol

2-(3-(2,6-dichlorophenylamino)-6-(phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-N,N-dimethylacetamide

1-(3-(diethylamino)propyl)-N3-(2,6-dimethylphenyl)-N6-phenyl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine

4-(2-(3-(2,6-dichlorophenylamino)-6-(phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)piperazin-1-ol

3-N-(2,6-dimethylphenyl)-1-(2-morpholin-4-ylethyl)-6-N-phenylpyrazolo[3,4-d]pyrimidine-3,6-diamine

2-(3-(2,6-dichlorophenylamino)-6-(phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-1-morpholinoethanone

(R)-1-(dimethylamino)-4-(3-(2,6-dimethylphenylamino)-6-(phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)butan-2-ol

3-N-(2,6-dimethylphenyl)-6-N-phenyl-1-(3-pyrrolidin-1-ylpropyl)pyrazolo[3,4-d]pyrimidine-3,6-diamine

1-(3-methoxy-3-methylbutyl)-N6-(4-(4-methylpiperazin-1-yl)phenyl)-N3-phenyl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine

1-(3-methoxy-3-methylbutyl)-6-N-phenyl-3-N-(2,4,6-trimethylphenyl)pyrazolo[3,4-d]pyrimidine-3,6-diamine

1-(3-methoxy-3-methylbutyl)-N3,N6-diphenyl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine