Brief Information of the Cell Line and Protein
Cell Line ID: CL000214 , BV-2
Synonyms
BV2
Category Transformed cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0182
Protein ID: PT01718 , Nitric oxide synthase, inducible
Gene Name NOS2
Organism Mus musculus, Mouse
Protein Classification Enzyme
Uniprot ID P29477
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000214  Protein ID: PT01718
 
Compound ID Compound Name Compound Formula
CP0405292
methyl (6R)-2-methyl-3-methylidene-6-[(4S,5S,10S,13R,14R,17R)-4,10,13-trimethyl-3,7,11-trioxo-1,2,4,5,6,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]heptanoate
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C30H42O5
 1
1
IC50 = 600 nM
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CP0499714
(E)-3-(3,4-dimethoxyphenyl)-1-[5-[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]-2,4-dihydroxyphenyl]prop-2-en-1-one
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C28H26O8
 1
1
IC50 = 950 nM
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CP0408034
methyl (6R)-2-methyl-3-methylidene-6-[(4S,5S,10S,13R,14R,17R)-4,10,13-trimethyl-3,11-dioxo-2,4,5,6,7,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]heptanoate
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C30H44O4
 1
1
IC50 = 1500 nM
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CP0381223
methyl (6R)-2-methyl-3-methylidene-6-[(4S,5S,10S,13R,14S,17R)-4,10,13-trimethyl-3,11-dioxo-2,4,5,6,7,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]heptanoate
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C30H44O4
 1
1
IC50 = 1600 nM
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CP0427886
methyl carbamimidothioate;sulfuric acid
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C2H8N2O4S2
 1
1
IC50 = 1800 nM
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CP0392856
(E)-3-(2,3-dimethoxyphenyl)-1-[5-[(E)-3-(2,3-dimethoxyphenyl)prop-2-enoyl]-2,4-dihydroxyphenyl]prop-2-en-1-one
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C28H26O8
 1
1
IC50 = 1820 nM
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CP0408035
methyl (6R)-6-[(4S,5S,7S,10S,13R,14R,17R)-7-hydroxy-4,10,13-trimethyl-3,11-dioxo-2,4,5,6,7,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-3-methylideneheptanoate
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C30H44O5
 1
1
IC50 = 2500 nM
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CP0425670
methyl (6R)-6-[(3R,4S,5S,10S,12S,13R,14R,17R)-3,12-dihydroxy-4,10,13-trimethyl-7-oxo-1,2,3,4,5,6,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-methyl-3-methylideneheptanoate
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C30H46O5
 1
1
IC50 = 2500 nM
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CP0505691
(6R)-2-methyl-3-methylidene-6-[(4S,5S,10S,13R,14R,17R)-4,10,13-trimethyl-3,7,11-trioxo-1,2,4,5,6,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]heptanoic acid
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C29H40O5
 1
1
IC50 = 3600 nM
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CP0520414
(11R,13S)-6,12,12-trimethyltricyclo[9.4.0.03,8]pentadeca-1,3(8),4,6-tetraene-5,13-diol
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C18H24O2
 1
1
IC50 = 3800 nM
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CP0476567
(E)-3-(furan-2-yl)-1-[5-[(E)-3-(furan-2-yl)prop-2-enoyl]-2,4-dihydroxyphenyl]prop-2-en-1-one
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C20H14O6
 1
1
IC50 = 4000 nM
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CP0379632
(6R)-2-methyl-3-methylidene-6-[(4S,5S,10S,13R,14R,17R)-4,10,13-trimethyl-3,11-dioxo-2,4,5,6,7,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]heptanoic acid
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C29H42O4
 1
1
IC50 = 4100 nM
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CP0404593
7beta,14alpha-dihydroxy-3,11-dioxo-4alpha-methylergosta-8,24(28)-dien-26-oic acid
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C29H42O5
 1
1
IC50 = 4200 nM
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CP0431514
5,7-dihydroxy-6-methoxy-2-(4-nitrophenyl)chromen-4-one
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C16H11NO7
 1
1
IC50 = 4730 nM
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CP0521858
(E)-1-[2,4-dihydroxy-5-[(E)-3-phenylprop-2-enoyl]phenyl]-3-phenylprop-2-en-1-one
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C24H18O4
 1
1
IC50 = 5440 nM
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CP0520413
(2S,4aS,10aR)-1,1,4a,7-tetramethyl-2,3,4,9,10,10a-hexahydrophenanthrene-2,6-diol
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C18H26O2
 1
1
IC50 = 5900 nM
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CP0002373
(1S,2R,5R,6R,9R,10R,13S,15S)-5-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-6,10-dimethyl-16,17-dioxapentacyclo[13.2.2.0^{1,9}.0^{2,6}.0^{10,15}]nonadec-18-en-13-ol
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C28H44O3
 1
1
IC50 = 6300 nM
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CP0496129
(E)-1-[2,4-dihydroxy-5-[(E)-3-(2,3,4-trimethoxyphenyl)prop-2-enoyl]phenyl]-3-(2,3,4-trimethoxyphenyl)prop-2-en-1-one
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C30H30O10
 1
1
IC50 = 7040 nM
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CP0906522
antrocamphin A
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C15H18O3
 1
1
IC50 = 7200 nM
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CP0553113
[(1R,2S,3S,5S,6R,7R,8S,9S,10R,11S,12S,13R,15R)-2,9,10,12-tetraacetyloxy-15-benzoyloxy-6-hydroxy-3,7,13-trimethyl-9-prop-1-en-2-yl-14-oxatetracyclo[11.1.1.01,5.06,11]pentadecan-8-yl] benzoate
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C42H48O14
 1
1
IC50 = 7500 nM
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CP0006392
5,7-Dihydroxy-8-methoxy-2-phenyl-chromen-4-one
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C16H12O5
 1
1
IC50 = 7800 nM
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CP0496128
(E)-1-[2,4-dihydroxy-5-[(E)-3-(3-methoxyphenyl)prop-2-enoyl]phenyl]-3-(3-methoxyphenyl)prop-2-en-1-one
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C26H22O6
 1
1
IC50 = 8090 nM
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CP0416276
2-(4-fluorophenyl)-5,7-dihydroxy-6-methoxychromen-4-one
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C16H11FO5
 1
1
IC50 = 8580 nM
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CP0496130
(E)-1-[2,4-dihydroxy-5-[(E)-3-pyridin-2-ylprop-2-enoyl]phenyl]-3-pyridin-2-ylprop-2-en-1-one
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C22H16N2O4
 1
1
IC50 = 8650 nM
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CP0404594
(6R)-6-[(3R,4S,5S,10S,13R,14R,17R)-3-hydroxy-4,10,13-trimethyl-7,11-dioxo-2,3,4,5,6,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-3-methylideneheptanoic acid
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C29H42O5
 1
1
IC50 = 9600 nM
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CP0553114
[(1R,2R,4S,5S,6R,7S,8R,9S,10R,11R,15S,16R,18S)-7,9-diacetyloxy-5,6,18-trihydroxy-4,8,16-trimethyl-13-phenyl-18-prop-1-en-2-yl-12,14,17-trioxapentacyclo[11.3.1.111,15.01,10.02,6]octadecan-8-yl] benzoate
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C38H44O12
 1
1
IC50 = 10200 nM
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CP0527557
2-(3-bromophenyl)-5,7-dihydroxy-6-methoxychromen-4-one
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C16H11BrO5
 1
1
IC50 = 10840 nM
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CP0425299
2-(3-fluorophenyl)-5,7-dihydroxy-6-methoxychromen-4-one
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C16H11FO5
 1
1
IC50 = 11420 nM
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CP0479570
Benzocamphorin B
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C15H16O4
 1
1
IC50 = 12100 nM
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CP0478601
(5S,9R,10S,13R,14R,17R)-17-[(E,2R,5S,6S)-7-hydroxy-5,6-dimethylhept-3-en-2-yl]-10,13-dimethyl-1,2,4,5,6,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
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C28H44O2
 1
1
IC50 = 12700 nM
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CP0043950
(S)-methyl 2-amino-5-(amino(nitroamino)methyleneamino)pentanoate
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C7H15N5O4
 2
1
IC50 = 13350 nM
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2
IC50 = 25800 nM
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CP0451583
[(1R,2S,3S,5S,6R,7R,8S,9S,10R,11S,12S,13R,15R)-2,8,10,12-tetraacetyloxy-9-benzoyloxy-6-hydroxy-3,7,13-trimethyl-9-prop-1-en-2-yl-14-oxatetracyclo[11.1.1.01,5.06,11]pentadecan-15-yl] benzoate
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C42H48O14
 1
1
IC50 = 13400 nM
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CP0478602
3alpha,7beta-dihydroxy-11-oxo-4alpha-methylergosta-8,24(28)-dien-26-oic acid
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C29H44O5
 1
1
IC50 = 15700 nM
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CP0499763
2,2',5,5'-tetramethoxy-3,4,3',4'-bi-methylenedioxy-6,6'-dimethylbiphenyl
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C20H22O8
 1
1
IC50 = 16200 nM
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CP0919913
zhankuic acid C
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C29H42O6
 1
1
IC50 = 16200 nM
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CP0914655
(E)-1-[5-Acetyl-2,4-dihydroxyphenyl]-3-(benzo[d][1,3]dioxol-5-yl)prop-2-en-1-one
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C18H14O6
 1
1
IC50 = 17740 nM
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CP0479571
(3S,10S,13R,14R,17R)-3,4,4,10,13,14-hexamethyl-17-[(2R)-6-methyl-5-methylideneheptan-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene
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C32H54
 1
1
IC50 = 22300 nM
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CP0476566
(E)-3-(2,5-dimethoxyphenyl)-1-[5-[(E)-3-(2,5-dimethoxyphenyl)prop-2-enoyl]-2,4-dihydroxyphenyl]prop-2-en-1-one
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C28H26O8
 1
1
IC50 = 23290 nM
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CP0474940
(3S,4aR,6aR,6aS,8aR,12aR,14aR,14bR)-4,4,6a,6a,8a,11,11,14b-octamethyl-1,2,3,4a,5,6,8,9,10,12,12a,13,14,14a-tetradecahydropicen-3-ol
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C30H50O
 1
1
IC50 = 24200 nM
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CP0496127
(E)-1-[2,4-dihydroxy-5-[(E)-3-(4-methoxyphenyl)prop-2-enoyl]phenyl]-3-(4-methoxyphenyl)prop-2-en-1-one
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C26H22O6
 1
1
IC50 = 25690 nM
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CP0499737
4,7-dimethoxy-5-methyl-1,3-benzodioxole
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C10H12O4
 1
1
IC50 = 29100 nM
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CP0520415
[(1R,2R,4S,5S,6R,7S,8R,9S,10S,11R,15S,16R,18S)-7-acetyloxy-5,6,9,18-tetrahydroxy-4,8,16-trimethyl-13-phenyl-18-prop-1-en-2-yl-12,14,17-trioxapentacyclo[11.3.1.111,15.01,10.02,6]octadecan-8-yl] benzoate
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C36H42O11
 1
1
IC50 > 30000 nM
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CP0298149
ERGOSTEROL
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C28H44O
 1
1
IC50 = 30600 nM
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CP0482047
(E)-1-[2,4-dihydroxy-5-[(E)-3-(5-methylfuran-2-yl)prop-2-enoyl]phenyl]-3-(5-methylfuran-2-yl)prop-2-en-1-one
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C22H18O6
 1
1
IC50 = 36310 nM
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CP0496169
(E)-1-[2,4-dihydroxy-5-[(E)-3-(3-methylthiophen-2-yl)prop-2-enoyl]phenyl]-3-(3-methylthiophen-2-yl)prop-2-en-1-one
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C22H18O4S2
 1
1
IC50 = 43270 nM
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CP0505817
(4aR,6aR,6aS,8aR,12aR,14aR,14bR)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one
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C30H48O
 1
1
IC50 = 46500 nM
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CP0033901
3,4,5-Trihydroxybenzoate, X
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C7H6O5
 1
1
IC50 > 50000 nM
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CP0039968
(6aS,6aS,6bR,8aR,12aR,14aR,14bS)-4,4,6a,6b,8a,11,11,14a-octamethyl-2,6,6a,7,8,9,10,12,12a,13,14,14b-dodecahydro-1H-picen-3-one
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C30H48O
 1
1
IC50 > 50000 nM
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CP0111043
5-alpha-stigmasta-7,22-diene-3beta-ol
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C29H48O
 1
1
IC50 > 50000 nM
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CP0260856
(4R,4aS,6aS,6aS,6bR,8aR,12aR,14aS,14bS)-4,4a,6a,6b,8a,11,11,14a-octamethyl-2,4,5,6,6a,7,8,9,10,12,12a,13,14,14b-tetradecahydro-1H-picen-3-one
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C30H50O
 1
1
IC50 > 50000 nM
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CP0294933
[(3S,4aR,6aR,6bS,8aR,12aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl] acetate
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C32H52O2
 1
1
IC50 > 50000 nM
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CP0424481
(3S,6S)-3-methyl-6-[[2-(2-methylbut-3-en-2-yl)-5,7-bis(3-methylbut-2-enyl)-1H-indol-3-yl]methyl]piperazine-2,5-dione
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C29H39N3O2
 1
1
IC50 > 50000 nM
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CP0434962
[(3S,6aS,6aS,6bR,8aR,12aR,14aR,14bS)-4,4,6a,6b,8a,11,11,14a-octamethyl-1,2,3,6,6a,7,8,9,10,12,12a,13,14,14b-tetradecahydropicen-3-yl] acetate
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C32H52O2
 1
1
IC50 > 50000 nM
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CP0434963
(2E)-2-[(1R,4aS,4bR,7S,8S,8aS,10R,10aS)-7,10-dihydroxy-1,4b,8-trimethyl-9-oxo-3,4,4a,5,6,7,8,8a,10,10a-decahydro-1H-phenanthren-2-ylidene]acetic acid
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C19H28O5
 1
1
IC50 > 50000 nM
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CP0439306
(4aR,6aR,6bS,8aR,12aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-octamethyl-2,4a,5,6,7,8,9,10,12,12a,14,14a-dodecahydro-1H-picen-3-one
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C30H48O
 1
1
IC50 > 50000 nM
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CP0493722
(3S,6R,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,6-diol
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C29H50O2
 1
1
IC50 > 50000 nM
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CP0522864
5-stigmasten-3beta,7beta-diol
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C29H50O2
 1
1
IC50 > 50000 nM
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CP0524327
(3S,6aS,6aS,6bR,8aR,12aR,14aR,14bS)-4,4,6a,6b,8a,11,11,14a-octamethyl-1,2,3,6,6a,7,8,9,10,12,12a,13,14,14b-tetradecahydropicen-3-ol
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C30H50O
 1
1
IC50 > 50000 nM
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CP0524328
(3S,5R,6R,7E,9R)-megastigman-7-ene-3,5,6,9-tetraol
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C13H24O4
 1
1
IC50 > 50000 nM
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CP0524329
(+)-pinitol
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C7H14O6
 1
1
IC50 > 50000 nM
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CP0726984
Afzelin
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C21H20O10
 1
1
IC50 > 50000 nM
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