Brief Information of the Cell Line and Protein
Cell Line ID: CL000068 , A-549
 Cell Line Info 
Synonyms
A 549
A549
NCI-A549
A549/ATCC
A549 ATCC
A549ATCC
hA549
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0023
Protein ID: PT01584 , Steroid 17-alpha-hydroxylase/17,20 lyase
 Protein Info 
Gene Name CYP17A1
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P05093
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000068
 Cell Line Info 
 Protein ID: PT01584
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0083501
 Compound Info 
6-fluoro-2-[(4-methylpyridin-3-yl)methyl]-3,4-dihydro-1H-[1]benzothiolo[2,3-c]pyridine
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C18H17FN2S
  1
1
IC50 = 20.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0154937
 Compound Info 
2-(pyridin-3-ylmethyl)-3,4-dihydro-1H-[1]benzothiolo[2,3-c]pyridin-6-ol
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C17H16N2OS
  1
1
IC50 = 23.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0328239
 Compound Info 
6-fluoro-2-(1H-imidazol-5-ylmethyl)-3,4-dihydro-1H-[1]benzothiolo[2,3-c]pyridine
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C15H14FN3S
  1
1
IC50 = 24.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0118930
 Compound Info 
6-fluoro-2-(pyridin-3-ylmethyl)-3,4-dihydro-1H-[1]benzothiolo[2,3-c]pyridine
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C17H15FN2S
  1
1
IC50 = 29 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0035494
 Compound Info 
(1S,2R,5S,10R,11S,15S)-2,15-dimethyl-14-(pyridin-3-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-7,13-dien-5-ol
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C24H31NO
  1
1
IC50 = 35.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0154936
 Compound Info 
6-fluoro-2-[(5-methoxypyridin-3-yl)methyl]-3,4-dihydro-1H-[1]benzothiolo[2,3-c]pyridine
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C18H17FN2OS
  1
1
IC50 = 45 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0203343
 Compound Info 
6-fluoro-2-[(5-fluoropyridin-3-yl)methyl]-3,4-dihydro-1H-[1]benzothiolo[2,3-c]pyridine
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C17H14F2N2S
  1
1
IC50 = 45.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS