| Compound ID |
Compound Name |
Compound Formula |
|
CP0471409
|
N-[2-[2-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]tetrazol-5-yl]-4,5-dimethoxyphenyl]quinoline-8-carboxamide
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|
C38H37N7O5
|
1
|
| 1 |
EC50 = 5.4 nM
|
|
|
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CP0471412
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N-[2-[2-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]tetrazol-5-yl]-4,5-dimethoxyphenyl]thiophene-3-carboxamide
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|
C33H34N6O5S
|
1
|
| 1 |
EC50 = 6.4 nM
|
|
|
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CP0559059
|
N-[2-[2-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]tetrazol-5-yl]-4,5-dimethoxyphenyl]-6-methyl-4-oxochromene-2-carboxamide
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|
C39H38N6O7
|
1
|
| 1 |
EC50 = 6.5 nM
|
|
|
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CP0557693
|
N-[2-[2-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]tetrazol-5-yl]-4,5-dimethoxyphenyl]-5-methoxy-4-oxochromene-2-carboxamide
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|
C39H38N6O8
|
1
|
| 1 |
EC50 = 7.4 nM
|
|
|
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CP0559058
|
N-[2-[2-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]tetrazol-5-yl]-4,5-dimethoxyphenyl]isoquinoline-1-carboxamide
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|
C38H37N7O5
|
1
|
| 1 |
EC50 = 7.6 nM
|
|
|
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CP0554575
|
N-[2-[2-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]tetrazol-5-yl]-4,5-dimethoxyphenyl]benzamide
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|
C35H36N6O5
|
1
|
| 1 |
EC50 = 7.7 nM
|
|
|
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CP0317641
|
Encequidar
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|
C38H36N6O7
|
1
|
| 1 |
EC50 = 7.9 nM
|
|
|
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CP0552262
|
N-[2-[2-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]tetrazol-5-yl]-4,5-dimethoxyphenyl]quinoline-3-carboxamide
Show/Hide
|
C38H37N7O5
|
1
|
| 1 |
EC50 = 7.9 nM
|
|
|
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CP0564666
|
N-[2-[2-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]tetrazol-5-yl]-4,5-dimethoxyphenyl]-6-fluoro-4-oxochromene-2-carboxamide
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|
C38H35FN6O7
|
1
|
| 1 |
EC50 = 8.1 nM
|
|
|
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CP0552264
|
N-[2-[2-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]tetrazol-5-yl]-4,5-dimethoxyphenyl]isoquinoline-3-carboxamide
Show/Hide
|
C38H37N7O5
|
1
|
| 1 |
EC50 = 8.5 nM
|
|
|
|
CP0552263
|
N-[2-[2-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]tetrazol-5-yl]-4,5-dimethoxyphenyl]-4-oxochromene-3-carboxamide
Show/Hide
|
C38H36N6O7
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0471410
|
N-[2-[2-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]tetrazol-5-yl]-4,5-dimethoxyphenyl]pyridine-3-carboxamide
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|
C34H35N7O5
|
1
|
| 1 |
EC50 = 9.1 nM
|
|
|
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CP0554574
|
N-[2-[2-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]tetrazol-5-yl]-4,5-dimethoxyphenyl]pyrazine-2-carboxamide
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|
C33H34N8O5
|
1
|
| 1 |
EC50 = 9.1 nM
|
|
|
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CP0559391
|
N-[2-[2-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]tetrazol-5-yl]-4,5-dimethoxyphenyl]isoquinoline-4-carboxamide
Show/Hide
|
C38H37N7O5
|
1
|
| 1 |
EC50 = 9.1 nM
|
|
|
|
CP0557692
|
N-[2-[2-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]tetrazol-5-yl]-4,5-dimethoxyphenyl]furan-3-carboxamide
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|
C33H34N6O6
|
1
|
| 1 |
EC50 = 10.2 nM
|
|
|
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CP0471411
|
N-[2-[2-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]tetrazol-5-yl]-4,5-dimethoxyphenyl]-3,4-difluorobenzamide
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|
C35H34F2N6O5
|
1
|
| 1 |
EC50 = 10.3 nM
|
|
|
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CP0558082
|
N-[2-[2-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]tetrazol-5-yl]-4,5-dimethoxyphenyl]naphthalene-2-carboxamide
Show/Hide
|
C39H38N6O5
|
1
|
| 1 |
EC50 = 10.3 nM
|
|
|
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CP0559057
|
N-[2-[2-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]tetrazol-5-yl]-4,5-dimethoxyphenyl]quinoline-2-carboxamide
Show/Hide
|
C38H37N7O5
|
1
|
| 1 |
EC50 = 12.1 nM
|
|
|
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CP0469476
|
(E)-1-[2-hydroxy-4,6-dimethoxy-3-(3-methylbut-2-enyl)phenyl]-3-(3-piperazin-1-ylphenyl)prop-2-en-1-one
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|
C26H32N2O4
|
1
|
| 1 |
IC50 = 1020 nM
|
|
|
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CP0470355
|
(E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(3-piperazin-1-ylphenyl)prop-2-en-1-one
Show/Hide
|
C21H24N2O4
|
1
|
| 1 |
IC50 = 2630 nM
|
|
|
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CP0470356
|
(E)-1-(3-butyl-2-hydroxy-4,6-dimethoxyphenyl)-3-(3-piperazin-1-ylphenyl)prop-2-en-1-one
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|
C25H32N2O4
|
1
|
| 1 |
IC50 = 3570 nM
|
|
|
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CP0520401
|
(E)-1-(2-hydroxy-4,6-dimethoxy-3-methylphenyl)-3-(3-piperazin-1-ylphenyl)prop-2-en-1-one
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|
C22H26N2O4
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
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CP0467887
|
(E)-1-(3-ethyl-2-hydroxy-4,6-dimethoxyphenyl)-3-(3-piperazin-1-ylphenyl)prop-2-en-1-one
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|
C23H28N2O4
|
1
|
| 1 |
IC50 = 4690 nM
|
|
|
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CP0467949
|
(E)-1-(2,4-dimethoxyphenyl)-3-(3-piperazin-1-ylphenyl)prop-2-en-1-one
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|
C21H24N2O3
|
1
|
| 1 |
IC50 = 4900 nM
|
|
|
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CP0559877
|
(E)-1-(2-hydroxy-4,6-dimethoxy-3-propylphenyl)-3-(3-piperazin-1-ylphenyl)prop-2-en-1-one
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|
C24H30N2O4
|
1
|
| 1 |
IC50 = 5120 nM
|
|
|
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CP0559879
|
(E)-1-[2-hydroxy-4,6-dimethoxy-3-(3-methylbut-2-enyl)phenyl]-3-[3-(trifluoromethyl)phenyl]prop-2-en-1-one
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|
C23H23F3O4
|
1
|
| 1 |
IC50 = 6260 nM
|
|
|
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CP0538108
|
(E)-1-[2-hydroxy-4,6-dimethoxy-3-(3-methylbut-2-enyl)phenyl]-3-(3-methoxyphenyl)prop-2-en-1-one
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|
C23H26O5
|
1
|
| 1 |
IC50 = 7860 nM
|
|
|
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CP0531045
|
(E)-1-[2-hydroxy-4,6-dimethoxy-3-(3-methylbut-2-enyl)phenyl]-3-(3-nitrophenyl)prop-2-en-1-one
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|
C22H23NO6
|
1
|
| 1 |
IC50 = 8830 nM
|
|
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CP0531044
|
(E)-3-(3-chlorophenyl)-1-[2-hydroxy-4,6-dimethoxy-3-(3-methylbut-2-enyl)phenyl]prop-2-en-1-one
Show/Hide
|
C22H23ClO4
|
1
|
| 1 |
IC50 = 9390 nM
|
|
|
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CP0036382
|
CAS_52-53-9
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|
C27H38N2O4
|
1
|
| 1 |
IC50 = 10100 nM
|
|
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CP0558802
|
(E)-3-(3-fluorophenyl)-1-[2-hydroxy-4,6-dimethoxy-3-(3-methylbut-2-enyl)phenyl]prop-2-en-1-one
Show/Hide
|
C22H23FO4
|
1
|
| 1 |
IC50 = 12640 nM
|
|
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CP0537984
|
(E)-1-[2-hydroxy-4,6-dimethoxy-3-(3-methylbut-2-enyl)phenyl]-3-(4-piperazin-1-ylphenyl)prop-2-en-1-one
Show/Hide
|
C26H32N2O4
|
1
|
| 1 |
IC50 = 14840 nM
|
|
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CP0467948
|
(E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-piperazin-1-ylphenyl)prop-2-en-1-one
Show/Hide
|
C21H24N2O4
|
1
|
| 1 |
IC50 = 16620 nM
|
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CP0571024
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(E)-3-[4-(dimethylamino)phenyl]-1-[2-hydroxy-4,6-dimethoxy-3-(3-methylbut-2-enyl)phenyl]prop-2-en-1-one
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|
C24H29NO4
|
1
|
| 1 |
IC50 = 17410 nM
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CP0557079
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(E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-[3-(4-methylpiperazin-1-yl)phenyl]prop-2-en-1-one
Show/Hide
|
C22H26N2O4
|
1
|
| 1 |
IC50 = 17960 nM
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CP0557961
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(E)-3-(4-fluorophenyl)-1-[2-hydroxy-4,6-dimethoxy-3-(3-methylbut-2-enyl)phenyl]prop-2-en-1-one
Show/Hide
|
C22H23FO4
|
1
|
| 1 |
IC50 = 17960 nM
|
|
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CP0531046
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(E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(3-morpholin-4-ylphenyl)prop-2-en-1-one
Show/Hide
|
C21H23NO5
|
1
|
| 1 |
IC50 = 18750 nM
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CP0435719
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tert-butyl 4-[3-[(E)-3-[2-hydroxy-4,6-dimethoxy-3-(3-methylbut-2-enyl)phenyl]-3-oxoprop-1-enyl]phenyl]piperazine-1-carboxylate
Show/Hide
|
C31H40N2O6
|
1
|
| 1 |
IC50 = 20070 nM
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CP0557979
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(E)-1-[2-hydroxy-4,6-dimethoxy-3-(3-methylbut-2-enyl)phenyl]-3-phenylprop-2-en-1-one
Show/Hide
|
C22H24O4
|
1
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| 1 |
IC50 = 20640 nM
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CP0551662
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(E)-1-[2-hydroxy-4,6-dimethoxy-3-(3-methylbut-2-enyl)phenyl]-3-(4-methoxyphenyl)prop-2-en-1-one
Show/Hide
|
C23H26O5
|
1
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| 1 |
IC50 = 20720 nM
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CP0559878
|
(E)-3-(4-chlorophenyl)-1-[2-hydroxy-4,6-dimethoxy-3-(3-methylbut-2-enyl)phenyl]prop-2-en-1-one
Show/Hide
|
C22H23ClO4
|
1
|
| 1 |
IC50 = 21780 nM
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CP0467885
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(E)-1-[2-hydroxy-4,6-dimethoxy-3-(3-methylbut-2-enyl)phenyl]-3-[3-(4-methylpiperazin-1-yl)phenyl]prop-2-en-1-one
Show/Hide
|
C27H34N2O4
|
1
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| 1 |
IC50 = 23590 nM
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CP0474242
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(E)-1-[2-hydroxy-4,6-dimethoxy-3-(3-methylbut-2-enyl)phenyl]-3-[4-(trifluoromethyl)phenyl]prop-2-en-1-one
Show/Hide
|
C23H23F3O4
|
1
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| 1 |
IC50 = 23590 nM
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CP0537986
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(E)-1-(2-hydroxy-4,6-dimethoxy-3-pentylphenyl)-3-(3-piperazin-1-ylphenyl)prop-2-en-1-one
Show/Hide
|
C26H34N2O4
|
1
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| 1 |
IC50 = 23590 nM
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CP0228529
|
CHEBI:70658
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|
C18H18O4
|
1
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| 1 |
IC50 = 24730 nM
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CP0559876
|
(E)-1-[2-hydroxy-4,6-dimethoxy-3-(3-methylbut-2-enyl)phenyl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
Show/Hide
|
C25H30O7
|
1
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| 1 |
IC50 = 26560 nM
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CP0558803
|
(E)-1-[2-hydroxy-4,6-dimethoxy-3-(3-methylbut-2-enyl)phenyl]-3-(2,3,4-trimethoxyphenyl)prop-2-en-1-one
Show/Hide
|
C25H30O7
|
1
|
| 1 |
IC50 = 27520 nM
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CP0459361
|
(E)-1-[2-hydroxy-4,6-dimethoxy-3-(3-methylbut-2-enyl)phenyl]-3-(3-morpholin-4-ylphenyl)prop-2-en-1-one
Show/Hide
|
C26H31NO5
|
1
|
| 1 |
IC50 = 31600 nM
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CP0469451
|
tert-butyl 4-[3-[(E)-3-(2-hydroxy-4,6-dimethoxyphenyl)-3-oxoprop-1-enyl]phenyl]piperazine-1-carboxylate
Show/Hide
|
C26H32N2O6
|
1
|
| 1 |
IC50 = 39950 nM
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CP0469475
|
(E)-3-[3-[4-(3,4-dimethoxybenzoyl)piperazin-1-yl]phenyl]-1-(2-hydroxy-4,6-dimethoxyphenyl)prop-2-en-1-one
Show/Hide
|
C30H32N2O7
|
1
|
| 1 |
IC50 = 42310 nM
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CP0470354
|
tert-butyl 4-[4-[(E)-3-[2-hydroxy-4,6-dimethoxy-3-(3-methylbut-2-enyl)phenyl]-3-oxoprop-1-enyl]phenyl]piperazine-1-carboxylate
Show/Hide
|
C31H40N2O6
|
1
|
| 1 |
IC50 = 52210 nM
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CP0571025
|
tert-butyl 4-[4-[(E)-3-(2-hydroxy-4,6-dimethoxyphenyl)-3-oxoprop-1-enyl]phenyl]piperazine-1-carboxylate
Show/Hide
|
C26H32N2O6
|
1
|
| 1 |
IC50 = 59230 nM
|
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