Brief Information of the Cell Line and Protein
Cell Line ID: CL000002 , K-562
Synonyms
K562
K.562
K 562
KO
GM05372
GM05372E
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0004
Protein ID: PT01546 , ATP-dependent translocase ABCB1
Gene Name ABCB1
Organism Homo sapiens, Human
Protein Classification Transporter
Uniprot ID P08183
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000002  Protein ID: PT01546
 
Compound ID Compound Name Compound Formula
CP0450496
[4-[methyl-[4-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxycyclohexyl]amino]cyclohexyl] 3,4,5-trimethoxybenzoate
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C35H47NO10
 1
1
IC50 = 12 nM
   TI
   LI
   LO
   TS
CP0396005
[4-[methyl-[4-[3-(3,4,5-trimethoxyphenyl)prop-2-ynoyloxy]cyclohexyl]amino]cyclohexyl] 3,4,5-trimethoxybenzoate
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C35H45NO10
 1
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
CP0514078
CHEMBL2316440
   Show/Hide
C41H49NO9
 1
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
CP0415038
[4-[methyl-[4-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxycyclohexyl]amino]cyclohexyl] 3,4,5-trimethoxybenzoate
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C35H47NO10
 1
1
IC50 = 30 nM
   TI
   LI
   LO
   TS
CP0384233
5-(anthracen-9-ylmethylamino)-2-(3,4-dimethoxyphenyl)-2-propan-2-ylpentanenitrile
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C31H34N2O2
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0497484
CHEMBL2316443
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C39H43NO7
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0396006
[4-[methyl-[4-[3-(3,4,5-trimethoxyphenyl)prop-2-ynoyloxy]cyclohexyl]amino]cyclohexyl] 3,4,5-trimethoxybenzoate
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C35H45NO10
 1
1
IC50 = 70 nM
   TI
   LI
   LO
   TS
CP0447974
CHEMBL1643346
   Show/Hide
C35H45NO10
 1
1
IC50 = 70 nM
   TI
   LI
   LO
   TS
CP0447976
[4-[methyl-[4-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxycyclohexyl]amino]cyclohexyl] 9H-fluorene-9-carboxylate
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C39H45NO7
 1
1
IC50 = 75 nM
   TI
   LI
   LO
   TS
CP0433660
[4-[methyl-[4-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxycyclohexyl]amino]cyclohexyl] 9H-fluorene-9-carboxylate
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C39H45NO7
 1
1
IC50 = 80 nM
   TI
   LI
   LO
   TS
CP0447977
[4-[methyl-[4-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxycyclohexyl]amino]cyclohexyl] 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexanoate
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C41H56N2O9
 1
1
IC50 = 80 nM
   TI
   LI
   LO
   TS
CP0497486
[4-[methyl-[4-[3-(3,4,5-trimethoxyphenyl)prop-2-ynoyloxy]cyclohexyl]amino]cyclohexyl] 3,4,5-trimethoxybenzoate
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C35H45NO10
 1
1
IC50 = 80 nM
   TI
   LI
   LO
   TS
CP0422658
[4-[methyl-[4-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxycyclohexyl]amino]cyclohexyl] 3,4,5-trimethoxybenzoate
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C35H47NO10
 1
1
IC50 = 92 nM
   TI
   LI
   LO
   TS
CP0450494
[4-[[4-[2,2-bis(4-methoxyphenyl)acetyl]oxycyclohexyl]-methylamino]cyclohexyl] 3-(3,4,5-trimethoxyphenyl)prop-2-ynoate
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C41H49NO9
 1
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
CP0508334
[4-[methyl-[4-[3-(3,4,5-trimethoxyphenyl)prop-2-ynoyloxy]cyclohexyl]amino]cyclohexyl] 9H-fluorene-9-carboxylate
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C39H43NO7
 1
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
CP0396004
CHEMBL2316437
   Show/Hide
C41H49NO9
 1
1
IC50 = 130 nM
   TI
   LI
   LO
   TS
CP0432012
[4-[methyl-[4-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxycyclohexyl]amino]cyclohexyl] 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexanoate
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C41H56N2O9
 1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS
CP0508335
[4-[[4-[2,2-bis(4-methoxyphenyl)acetyl]oxycyclohexyl]-methylamino]cyclohexyl] 3-(3,4,5-trimethoxyphenyl)prop-2-ynoate
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C41H49NO9
 1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS
CP0422628
[4-[methyl-[4-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxycyclohexyl]amino]cyclohexyl] 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexanoate
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C41H56N2O9
 1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
CP0447968
[4-[methyl-[4-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxycyclohexyl]amino]cyclohexyl] 9H-fluorene-9-carboxylate
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C39H45NO7
 1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
CP0450495
CHEMBL2316435
   Show/Hide
C39H45NO7
 1
1
IC50 = 180 nM
   TI
   LI
   LO
   TS
CP0489899
CHEMBL2316429
   Show/Hide
C41H56N2O9
 1
1
IC50 = 240 nM
   TI
   LI
   LO
   TS
CP0422669
[4-[methyl-[4-[3-(3,4,5-trimethoxyphenyl)prop-2-ynoyloxy]cyclohexyl]amino]cyclohexyl] 9H-fluorene-9-carboxylate
   Show/Hide
C39H43NO7
 1
1
IC50 = 290 nM
   TI
   LI
   LO
   TS
CP0476583
CHEMBL2316160
   Show/Hide
C35H47NO10
 1
1
IC50 = 320 nM
   TI
   LI
   LO
   TS
CP0396008
[4-[methyl-[4-[3-(3,4,5-trimethoxyphenyl)propanoyloxy]cyclohexyl]amino]cyclohexyl] 3,4,5-trimethoxybenzoate
   Show/Hide
C35H49NO10
 1
1
IC50 = 350 nM
   TI
   LI
   LO
   TS
CP0450493
[4-[methyl-[4-[3-(3,4,5-trimethoxyphenyl)prop-2-ynoyloxy]cyclohexyl]amino]cyclohexyl] 9H-fluorene-9-carboxylate
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C39H43NO7
 1
1
IC50 = 500 nM
   TI
   LI
   LO
   TS
CP0514079
[4-[methyl-[4-[3-(3,4,5-trimethoxyphenyl)propanoyloxy]cyclohexyl]amino]cyclohexyl] 3,4,5-trimethoxybenzoate
   Show/Hide
C35H49NO10
 1
1
IC50 = 610 nM
   TI
   LI
   LO
   TS
CP0415037
[4-[methyl-[4-[3-(3,4,5-trimethoxyphenyl)propanoyloxy]cyclohexyl]amino]cyclohexyl] 3,4,5-trimethoxybenzoate
   Show/Hide
C35H49NO10
 1
1
IC50 = 630 nM
   TI
   LI
   LO
   TS
CP0447967
CHEMBL1643342
   Show/Hide
C35H49NO10
 1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0036382
CAS_52-53-9
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C27H38N2O4
 1
1
IC50 = 1600 nM
   TI
   LI
   LO
   TS