Brief Information of the Cell Line and Protein
Cell Line ID: CL000059 , HuT 78
 Cell Line Info 
Synonyms
Hut 78
HUT 78
HuT-78
HUT-78
HuT78
Hut78
HUT78
NCI-H78
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0337
Protein ID: PT01508 , C-C chemokine receptor type 4
 Protein Info 
Gene Name CCR4
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P51679
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000059
 Cell Line Info 
 Protein ID: PT01508
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0094303
 Compound Info 
N-[(2,4-dichlorophenyl)methyl]-2-[2-[[(2R)-pyrrolidin-2-yl]methyl]-2,8-diazaspiro[4.5]decan-8-yl]pyrimidin-4-amine
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C24H32Cl2N6
  1
1
EC50 = 6.31 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0300639
 Compound Info 
[4-[4-[(2,4-dichlorophenyl)methylamino]pyrido[2,3-d]pyrimidin-2-yl]piperazin-1-yl]-[(2R)-piperidin-2-yl]methanone
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C24H27Cl2N7O
  1
1
EC50 = 10 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0307739
 Compound Info 
N-[(2,4-dichlorophenyl)methyl]-2-[2-[[(2S)-pyrrolidin-2-yl]methyl]-2,8-diazaspiro[4.5]decan-8-yl]pyrimidin-4-amine
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C24H32Cl2N6
  1
1
EC50 = 12.59 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0307741
 Compound Info 
N-[(2,4-difluorophenyl)methyl]-2-[2-(pyrrolidin-2-ylmethyl)-2,8-diazaspiro[4.5]decan-8-yl]pyrimidin-4-amine
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C24H32F2N6
  1
1
EC50 = 15.85 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0234242
 Compound Info 
N-[(2,4-dichlorophenyl)methyl]-N-methyl-2-[2-(pyrrolidin-2-ylmethyl)-2,8-diazaspiro[4.5]decan-8-yl]pyrimidin-4-amine
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C25H34Cl2N6
  1
1
EC50 = 158.49 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0385056
 Compound Info 
(2R)-N-[1-[4-(4-chloro-2-fluoroanilino)-6,7-dimethoxyquinazolin-2-yl]piperidin-4-yl]-N-methylpyrrolidine-2-carboxamide
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C27H32ClFN6O3
  1
1
EC50 = 398.11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS