Brief Information of the Cell Line and Protein
Cell Line ID: CL000085 , J1
Synonyms
ES-J1
Category Embryonic stem cell
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_6412
Protein ID: PT01480 , 5-hydroxytryptamine receptor 2C
Gene Name HTR2C
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID P08909
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000085  Protein ID: PT01480
 
Compound ID Compound Name Compound Formula
CP0045155
2,5-dimethoxy-4-bromophenethylamine
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C10H14BrNO2
 1
1
Ki = 36 nM
   TI
   LI
   LO
   TS
CP0038318
(4-Bromo-benzyl)-[2-(4-bromo-2,5-dimethoxy-phenyl)-ethyl]-amine
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C17H19Br2NO2
 1
1
Ki = 48 nM
   TI
   LI
   LO
   TS
CP0347823
Benzyl-[2-(4-bromo-2,5-dimethoxy-phenyl)-ethyl]-amine
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C17H20BrNO2
 1
1
Ki = 90 nM
   TI
   LI
   LO
   TS
CP0185216
2-(4-bromo-2,5-dimethoxyphenyl)-N-methylethanamine
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C11H16BrNO2
 1
1
Ki = 100 nM
   TI
   LI
   LO
   TS
CP0209318
(4-Bromo-benzyl)-[2-(5-methoxy-1H-indol-3-yl)-ethyl]-amine
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C18H19BrN2O
 1
1
Ki = 100 nM
   TI
   LI
   LO
   TS
CP0208313
2-(4-bromo-2,5-dimethoxyphenyl)-N-[(4-iodophenyl)methyl]ethanamine
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C17H19BrINO2
 1
1
Ki = 165 nM
   TI
   LI
   LO
   TS
CP0211930
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-3-phenylpropan-1-amine
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C20H24N2O
 1
1
Ki = 165 nM
   TI
   LI
   LO
   TS
CP0217672
2-(4-bromo-2,5-dimethoxyphenyl)-N-[(4-methoxyphenyl)methyl]ethanamine
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C18H22BrNO3
 1
1
Ki = 215 nM
   TI
   LI
   LO
   TS
CP0049759
2-(4-bromo-2,5-dimethoxyphenyl)-N-[(4-methylphenyl)methyl]ethanamine
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C18H22BrNO2
 1
1
Ki = 225 nM
   TI
   LI
   LO
   TS
CP0209192
N-[2-(4-bromo-2,5-dimethoxyphenyl)ethyl]-3-phenylpropan-1-amine
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C19H24BrNO2
 1
1
Ki = 310 nM
   TI
   LI
   LO
   TS
CP0214254
2-(4-bromo-2,5-dimethoxyphenyl)-N-[(4-fluorophenyl)methyl]ethanamine
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C17H19BrFNO2
 1
1
Ki = 360 nM
   TI
   LI
   LO
   TS
CP0310397
Benzyl-[2-(5-methoxy-1H-indol-3-yl)-ethyl]-amine
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C18H20N2O
 1
1
Ki = 370 nM
   TI
   LI
   LO
   TS
CP0095892
2-(4-bromo-2,5-dimethoxyphenyl)-N,N-dimethylethanamine
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C12H18BrNO2
 1
1
Ki = 480 nM
   TI
   LI
   LO
   TS
CP0034894
2-(5-methoxy-1H-indol-3-yl)ethanamine
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C11H14N2O
 1
1
Ki = 500 nM
   TI
   LI
   LO
   TS
CP0306453
N-[2-(4-bromo-2,5-dimethoxyphenyl)ethyl]-4-phenylbutan-1-amine
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C20H26BrNO2
 1
1
Ki = 695 nM
   TI
   LI
   LO
   TS
CP0208748
2-(4-bromo-2,5-dimethoxyphenyl)-N-[(4-chlorophenyl)methyl]ethanamine
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C17H19BrClNO2
 1
1
Ki = 715 nM
   TI
   LI
   LO
   TS
CP0038174
2-(5-methoxy-1H-indol-3-yl)-N-methylethanamine
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C12H16N2O
 1
1
Ki = 840 nM
   TI
   LI
   LO
   TS
CP0071154
2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamine
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C13H18N2O
 1
1
Ki = 960 nM
   TI
   LI
   LO
   TS
CP0045485
4-{[2-(4-Bromo-2,5-dimethoxy-phenyl)-ethylamino]-methyl}-phenylamine
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C17H21BrN2O2
 1
1
Ki = 1020 nM
   TI
   LI
   LO
   TS
CP0040981
(4-Methoxy-benzyl)-[2-(5-methoxy-1H-indol-3-yl)-ethyl]-amine
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C19H22N2O2
 1
1
Ki = 1180 nM
   TI
   LI
   LO
   TS
CP0226641
2-(4-bromo-2,5-dimethoxyphenyl)-N-[(4-nitrophenyl)methyl]ethanamine
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C17H19BrN2O4
 1
1
Ki = 1220 nM
   TI
   LI
   LO
   TS
CP0110440
2-(5-methoxy-1H-indol-3-yl)-N-[(4-methylphenyl)methyl]ethanamine
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C19H22N2O
 1
1
Ki = 1225 nM
   TI
   LI
   LO
   TS
CP0311155
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-4-phenylbutan-1-amine
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C21H26N2O
 1
1
Ki = 1500 nM
   TI
   LI
   LO
   TS
CP0345958
(4-Iodo-benzyl)-[2-(5-methoxy-1H-indol-3-yl)-ethyl]-amine
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C18H19IN2O
 1
1
Ki = 1770 nM
   TI
   LI
   LO
   TS
CP0209098
2-(4-bromo-2,5-dimethoxyphenyl)-N-ethylethanamine
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C12H18BrNO2
 1
1
Ki = 1930 nM
   TI
   LI
   LO
   TS
CP0347820
1-[2-(4-Bromo-2,5-dimethoxy-phenyl)-ethyl]-piperidine
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C15H22BrNO2
 1
1
Ki = 2530 nM
   TI
   LI
   LO
   TS
CP0099718
N-ethyl-2-(5-methoxy-1H-indol-3-yl)ethanamine
   Show/Hide
C13H18N2O
 1
1
Ki = 2675 nM
   TI
   LI
   LO
   TS
CP0165621
(4-Fluoro-benzyl)-[2-(5-methoxy-1H-indol-3-yl)-ethyl]-amine
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C18H19FN2O
 1
1
Ki = 3530 nM
   TI
   LI
   LO
   TS
CP0196679
(4-Chloro-benzyl)-[2-(5-methoxy-1H-indol-3-yl)-ethyl]-amine
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C18H19ClN2O
 1
1
Ki = 4390 nM
   TI
   LI
   LO
   TS
CP0136625
4-{[2-(5-Methoxy-1H-indol-3-yl)-ethylamino]-methyl}-phenylamine
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C18H21N3O
 1
1
Ki = 6700 nM
   TI
   LI
   LO
   TS
CP0219592
2-(5-methoxy-1H-indol-3-yl)-N-[(4-nitrophenyl)methyl]ethanamine
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C18H19N3O3
 1
1
Ki = 9970 nM
   TI
   LI
   LO
   TS
CP0049854
5-Methoxy-3-(2-piperidin-1-yl-ethyl)-1H-indole
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C16H22N2O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS