Brief Information of the Cell Line and Protein
Cell Line ID: CL000026 , CHO-K1
 Cell Line Info 
Synonyms
CHO K1
CHOK1
CHO cell clone K1
GM15452
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0214
Protein ID: PT01480 , 5-hydroxytryptamine receptor 2C
 Protein Info 
Gene Name HTR2C
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID P08909
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000026
 Cell Line Info 
 Protein ID: PT01480
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0403928
 Compound Info 
8-[5-(5-chloro-2,4-dimethoxyphenyl)-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
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C20H26ClN3O5
  1
1
Ki = 0.631 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0467080
 Compound Info 
4-chloro-N-[3-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-4-methoxyphenyl]benzenesulfonamide
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C25H29ClN4O6S
  1
1
Ki = 1.995 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0441834
 Compound Info 
8-[5-(2-methoxy-5-phenoxyphenyl)-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
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C25H29N3O5
  1
1
Ki = 3.162 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0415489
 Compound Info 
N-[3-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-4-methoxyphenyl]benzenesulfonamide
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C25H30N4O6S
  1
1
Ki = 6.31 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0415488
 Compound Info 
8-[5-(5-amino-2,4-dimethoxyphenyl)-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
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C20H28N4O5
  1
1
Ki = 39.81 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0391396
 Compound Info 
N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]-3-(trifluoromethyl)benzenesulfonamide
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C27H31F3N4O7S
  1
1
Ki = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS