Compound ID |
Compound Name |
Compound Formula |
CP0452579
|
3-(2-(3-tert-Butylphenyl)-5-((dimethylamino)methyl)-2H-1,2,4-triazol-3-yl)phenol
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C21H26N4O
|
1
|
1 |
IC50 = 46.3 nM
|
|
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CP0390376
|
3-(5-(3-tert-Butylphenyl)-3-((dimethylamino)methyl)-1H-1,2,4-triazol-1-yl)phenol
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C21H26N4O
|
1
|
1 |
IC50 = 341 nM
|
|
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CP0390387
|
3-(3-((Dimethylamino)methyl)-5-(2,4-dimethylphenyl)-1H-1,2,4-triazol-1-yl)phenol
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C19H22N4O
|
1
|
1 |
IC50 = 351 nM
|
|
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CP0373889
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3-(2-(4-tert-Butylphenyl)-5-((dimethylamino)methyl)-2H-1,2,4-triazol-3-yl)phenol
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C21H26N4O
|
1
|
1 |
IC50 = 760 nM
|
|
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CP0041255
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(+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide
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C28H39N3O2
|
1
|
1 |
IC50 = 3601 nM
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|
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CP0038385
|
3-(5-(4-tert-butylphenyl)-3-((dimethylamino)methyl)-1H-1,2,4-triazol-1-yl)phenol
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C21H26N4O
|
1
|
1 |
IC50 = 3851 nM
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|
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CP0373269
|
(5-(2,4-Dimethylphenyl)-1-(3-methoxyphenyl)-1H-1,2,4-triazol-3-yl)-N,N-dimethylmethanamine
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C20H24N4O
|
1
|
1 |
IC50 > 10000 nM
|
|
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CP0373884
|
(5-(4-tert-Butylphenyl)-1-(3-methoxyphenyl)-1H-1,2,4-triazol-3-yl)-N,N-dimethylmethanamine
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|
C22H28N4O
|
1
|
1 |
IC50 > 10000 nM
|
|
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CP0417784
|
(1-(4-tert-Butylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazol-3-yl)-N,N-dimethylmethanamine
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|
C22H28N4O
|
1
|
1 |
IC50 > 10000 nM
|
|
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CP0452580
|
(1-(3-tert-Butylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazol-3-yl)-N,N-dimethylmethanamine
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|
C22H28N4O
|
1
|
1 |
IC50 > 10000 nM
|
|
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CP0510367
|
(5-(3-tert-Butylphenyl)-1-(3-methoxyphenyl)-1H-1,2,4-triazol-3-yl)-N,N-dimethylmethanamine
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C22H28N4O
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0035617
|
N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]decan-8-yl]acetamide
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|
C22H32N2O2
|
1
|
1 |
Kd = 1 nM
|
|
|
CP0054764
|
2-[(1S,2S,13R,21R)-22-(cyclopropylmethyl)-2,16-dihydroxy-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaen-7-yl]guanidine
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|
C27H29N5O3
|
3
|
1 |
Ki = 0.03 nM
|
|
|
2 |
Ki = 0.18 nM
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|
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3 |
Ki = 3.9 nM
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|
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CP0041449
|
C18130
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C40H43N3O6
|
4
|
1 |
Ki = 0.07 nM
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|
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2 |
Ki = 0.24 nM
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|
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3 |
Ki = 0.244 nM
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4 |
Ki = 1.39 nM
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CP0430310
|
5'-Amidinomethyl-17-cyclopropylmethyl-6,7-didehydro-4,5alpha-epoxy-3,14-dihydroxyindolo[2',3':6,7]morphinan
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|
C28H30N4O3
|
1
|
1 |
Ki = 0.214 nM
|
|
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CP0409091
|
5'-N-Biguanidino-17-cyclopropylmethyl-6,7-didehydro-4,5alpha-epoxy-3,14-dihydroxyindolo[2',3':6,7]morphinan
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|
C28H31N7O3
|
1
|
1 |
Ki = 0.226 nM
|
|
|
CP0848535
|
5'-(Trimethylammonium)methyl-17-cyclopropylmethyl-6,7-didehydro-4,5alpha-epoxy-3,14-dihydroxyindolo[2',3':6,7]morphinan Iodide
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|
C30H36IN3O3
|
1
|
1 |
Ki = 0.354 nM
|
|
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CP0377768
|
2-[2-[(1S,2S,13R,21R)-22-(cyclopropylmethyl)-2,16-dihydroxy-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaen-7-yl]ethyl]guanidine
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|
C29H33N5O3
|
1
|
1 |
Ki = 0.507 nM
|
|
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CP0405336
|
5'-Amidino-17-cyclopropylmethyl-6,7-didehydro-4,5alpha-epoxy-3,14-dihydroxyindolo[2',3':6,7]morphinan
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|
C27H28N4O3
|
1
|
1 |
Ki = 0.529 nM
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|
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CP0381067
|
2-[[(1S,2S,13R,21R)-22-(cyclopropylmethyl)-2,16-dihydroxy-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaen-7-yl]methyl]guanidine
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|
C28H31N5O3
|
1
|
1 |
Ki = 0.745 nM
|
|
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CP0505602
|
5'-(Dimethylamino)methyl-17-cyclopropylmethyl-6,7-didehydro-4,5alpha-epoxy-3,14-dihydroxyindolo[2',3':6,7]morphinan
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|
C29H33N3O3
|
1
|
1 |
Ki = 0.823 nM
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|
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CP0050068
|
(1S,2S,13R,21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol
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|
C26H26N2O3
|
3
|
1 |
Ki = 1.23 nM
|
|
|
2 |
Ki = 25.5 nM
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|
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3 |
Ki = 42 nM
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|
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CP0048724
|
(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride
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|
C20H23NO4
|
3
|
1 |
Ki = 1.8 nM
|
|
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2 |
Ki = 4.2 nM
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3 |
Ki = 12.7 nM
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CP0402523
|
6,7-Dihydro-4,5alpha-epoxy-5'-guanidinyl-17-methyl-3,14-dihydroxyindolo[2',3':6,7]morphinan
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|
C24H25N5O3
|
1
|
1 |
Ki = 2.83 nM
|
|
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CP0036843
|
(2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(furan-3-yl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho-[2,1-c]pyran-7-carboxylic acid methyl ester
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|
C23H28O8
|
1
|
1 |
Ki = 4 nM
|
|
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CP0182209
|
5'-[N-(N'-Cyano)guanidinyl]-17-cyclopropylmethyl-6,7-didehydro-4,5alpha-epoxy-3,14-dihydroxyindolo[2',3':6,7]morphinan
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|
C28H28N6O3
|
1
|
1 |
Ki = 4.46 nM
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|
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CP0505690
|
(3S,4aR,4bS,6S,8R,8aR)-6-Acetoxy-3-furan-3-yl-4a,8a-dimethyl-5-oxo-4,4a,4b,5,6,7,8,8a,9,10-decahydro-3H-2-oxa-phenanthrene-8-carboxylic acid methyl ester
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|
C23H28O7
|
1
|
1 |
Ki = 6 nM
|
|
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CP0510348
|
(3S,4aS,4bR,6S,8R,8aR,10aR)-6-Acetoxy-3-furan-3-yl-4a,8a-dimethyl-5-oxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester
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|
C23H30O7
|
1
|
1 |
Ki = 6 nM
|
|
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CP0169508
|
(3S,4aR,4bS,6R,8R,8aR,10aR)-6-Acetoxy-3-furan-3-yl-4a,8a-dimethyl-1-oxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester
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|
C23H30O7
|
1
|
1 |
Ki = 18 nM
|
|
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CP0395488
|
(3S,4aR,4bS,6S,8R,8aR,10aR)-6-Formyloxy-3-furan-3-yl-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester
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|
C22H26O8
|
1
|
1 |
Ki = 18 nM
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|
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CP0676197
|
N-(2-(Benzyl(tert-butyl)amino)ethyl)-2-tosyl-1,2,3,4-tetrahydroisoquinoline-6-carboxamide
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|
C30H37N3O3S
|
1
|
1 |
Ki = 37 nM
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|
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CP0058181
|
4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[2-[(phenylmethyl)-propan-2-yl-amino]ethyl]benzamide
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|
C27H33N3O3S
|
1
|
1 |
Ki = 50 nM
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|
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CP0717802
|
N-(2-((4-Chlorobenzyl)(tert-butyl)amino)ethyl)-2-tosyl-1,2,3,4-tetrahydroisoquinoline-6-carboxamide
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|
C30H36ClN3O3S
|
1
|
1 |
Ki = 53 nM
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CP0096567
|
7-(2'-spiroindanyl)oxymorphone
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|
C25H25NO4
|
3
|
1 |
Ki = 55 nM
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|
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2 |
Ki = 292 nM
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3 |
Ki = 488 nM
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CP0494837
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(3S,4aS,4bR,6S,8R,8aR,10aR)-6-Acetoxy-3-furan-3-yl-1-hydroxy-4a,8a-dimethyl-5-oxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester
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|
C23H30O8
|
1
|
1 |
Ki = 59 nM
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CP0667615
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N-(2-((4-Bromobenzyl)(isopropyl)amino)ethyl)-2-tosyl-1,2,3,4-tetrahydroisoquinoline-6-carboxamide
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|
C29H34BrN3O3S
|
1
|
1 |
Ki = 73 nM
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|
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CP0048256
|
10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one
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|
C17H19NO4
|
3
|
1 |
Ki = 95 nM
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2 |
Ki = 208 nM
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3 |
Ki = 435 nM
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CP0378873
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(2S,4aR,6aR,7R,9S,10aS,10bR)-methyl 9-acetoxy-6a,10b-dimethyl-4,10-dioxo-2-((R)-tetrahydrofuran-3-yl)-dodecahydro-1H-benzo[f]isochromene-7-carboxylate
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|
C23H32O8
|
1
|
1 |
Ki = 156 nM
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CP0391557
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(3S,4aR,4bS,6S,8R,8aR,10aS)-6-Acetoxy-3-furan-3-yl-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester
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|
C23H28O8
|
1
|
1 |
Ki = 163 nM
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CP0378809
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(2S,4aR,6aS,7R,9S,10aS,10bR)-2-(furan-3-yl)-7-(hydroxymethyl)-6a,10b-dimethyl-4,10-dioxo-dodecahydro-1H-benzo[f]isochromen-9-yl acetate
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|
C22H28O7
|
1
|
1 |
Ki = 347 nM
|
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CP0515409
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(3S,4aR,4bR,5R,6S,8aR,10aR)-5,6-Diacetoxy-3-furan-3-yl-4a,8a-dimethyl-1-oxo-3,4,4a,4b,5,6,8a,9,10,10a-decahydro-1H-2-oxa-phenanthrene-8-carboxylic acid methyl ester
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|
C25H30O9
|
1
|
1 |
Ki = 1022 nM
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CP0860586
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(3S,4aR,4bS,5R,6S,8R,8aR,10aR)-5-Acetoxy-3-furan-3-yl-6-hydroxy-4a,8a-dimethyl-1-oxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester
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|
C23H30O8
|
1
|
1 |
Ki = 1125 nM
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CP0384142
|
(S,E)-(2,3,5,6,7,9a-hexahydro-1H-pyrrolo[1,2-a]azepin-9-yl)(2-hydroxy-6-methylphenyl)methanone
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|
C17H21NO2
|
1
|
1 |
Ki = 4000 nM
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CP0050256
|
(3S,4aR,4bS,5R,6S,8R,8aR,10aR)-5,6-Diacetoxy-3-furan-3-yl-4a,8a-dimethyl-1-oxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester
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|
C25H32O9
|
1
|
1 |
Ki > 10000 nM
|
|
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CP0496079
|
(3S,4aR,4bR,5R,6S,8aR,10aR)-5-Acetoxy-3-furan-3-yl-6-hydroxy-4a,8a-dimethyl-1-oxo-3,4,4a,4b,5,6,8a,9,10,10a-decahydro-1H-2-oxa-phenanthrene-8-carboxylic acid methyl ester
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|
C23H28O8
|
1
|
1 |
Ki > 10000 nM
|
|
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CP0510347
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(3S,4aR,4bR,5R,6S,8aR,10aR)-6-Acetoxy-3-furan-3-yl-5-hydroxy-4a,8a-dimethyl-1-oxo-3,4,4a,4b,5,6,8a,9,10,10a-decahydro-1H-2-oxa-phenanthrene-8-carboxylic acid methyl ester
Show/Hide
|
C23H28O8
|
1
|
1 |
Ki > 10000 nM
|
|
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CP0134916
|
1-{3-[3-(tert-butyl) phenyl]-5-N,N-dimethylaminomethyl-(1,2,4-triazol-4-yl) }-3-phenol
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|
C21H26N4O
|
1
|
1 |
Ki > 10000 nM
|
|
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CP0221707
|
1-{3-[4-(tert-butyl) phenyl]-5-N,N-dimethylaminomethyl-(1,2,4-triazol-4-yl)}-3-phenol
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|
C21H26N4O
|
1
|
1 |
Ki > 10000 nM
|
|
|
CP0850124
|
elaeocarpenine
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|
C16H19NO2
|
1
|
1 |
Ki = 12000 nM
|
|
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CP0501690
|
(S)-(1,2,3,5,6,8a-hexahydroindolizin-8-yl)(2-methoxy-6-methylphenyl)methanone
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|
C17H21NO2
|
1
|
1 |
Ki = 20000 nM
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CP0390056
|
(S)-(1,2,3,5,6,8a-hexahydroindolizin-8-yl)(2-hydroxy-6-methylphenyl)methanone
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|
C16H19NO2
|
1
|
1 |
Ki = 24000 nM
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CP0498934
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(S)-(2-hydroxy-6-methylphenyl)(2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl)methanone
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|
C15H17NO2
|
1
|
1 |
Ki = 35000 nM
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CP0384140
|
(S)-(1,2,3,5,6,8a-hexahydroindolizin-8-yl)(2-hydroxyphenyl)methanone
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|
C15H17NO2
|
1
|
1 |
Ki = 83000 nM
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