| Compound ID |
Compound Name |
Compound Formula |
|
CP0051607
|
4-[3-(8-methyl-4-oxo-3H-quinazolin-2-yl)propanoylamino]-N-quinolin-8-ylbenzamide
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|
C28H23N5O3
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
|
CP0468693
|
6-fluoro-2-[4-(2-hydroxypropan-2-yl)phenyl]-8-methyl-3H-quinazolin-4-one
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|
C18H17FN2O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0533784
|
6-fluoro-8-methyl-2-(4-piperidin-4-ylphenyl)-3H-quinazolin-4-one;hydrochloride
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|
C20H21ClFN3O
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0458123
|
2-[4-(2-hydroxypropan-2-yl)phenyl]-8-methyl-3H-quinazolin-4-one
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|
C18H18N2O2
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0550942
|
6-fluoro-2-[4-[2-(2-hydroxyethoxy)propan-2-yl]phenyl]-8-methyl-3H-quinazolin-4-one
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|
C20H21FN2O3
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0485970
|
6-fluoro-8-methyl-2-[4-(4-methylpiperazin-1-yl)phenyl]-3H-quinazolin-4-one
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|
C20H21FN4O
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0053018
|
2-(4-(Trifluoromethyl)phenyl)-7,8-dihydro-5H-thiopyrano-[4,3-d]pyrimidin-4-ol
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|
C14H11F3N2OS
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0485991
|
6-fluoro-8-methyl-2-[4-(1-methylpiperidin-4-yl)phenyl]-3H-quinazolin-4-one
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|
C21H22FN3O
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0458121
|
2-(4-tert-butylphenyl)-6-fluoro-3H-quinazolin-4-one
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|
C18H17FN2O
|
1
|
| 1 |
IC50 = 3.6 nM
|
|
|
|
CP0346125
|
6,8-difluoro-2-[4-(2-hydroxypropan-2-yl)phenyl]-3H-quinazolin-4-one
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|
C17H14F2N2O2
|
2
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
IC50 = 9.2 nM
|
|
|
|
CP0528969
|
5,6-difluoro-2-[4-(2-hydroxypropan-2-yl)phenyl]-3H-quinazolin-4-one
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|
C17H14F2N2O2
|
1
|
| 1 |
IC50 = 7.5 nM
|
|
|
|
CP0251373
|
2-(4-tert-butylphenyl)-3H-quinazolin-4-one
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|
C18H18N2O
|
1
|
| 1 |
IC50 = 8.7 nM
|
|
|
|
CP0134483
|
2-[2-[[4-[(Z)-(7-carbamoyl-3-oxo-1-benzofuran-2-ylidene)methyl]benzoyl]amino]ethyl]-1H-benzimidazole-4-carboxamide
Show/Hide
|
C27H21N5O5
|
1
|
| 1 |
IC50 = 8.8 nM
|
|
|
|
CP0468687
|
6-fluoro-2-[4-(2-hydroxypropan-2-yl)phenyl]-3H-quinazolin-4-one
Show/Hide
|
C17H15FN2O2
|
1
|
| 1 |
IC50 = 10.5 nM
|
|
|
|
CP0481807
|
6-fluoro-2-[4-(4-methylpiperazin-1-yl)phenyl]-3H-quinazolin-4-one
Show/Hide
|
C19H19FN4O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0482822
|
8-chloro-2-[4-(2-hydroxypropan-2-yl)phenyl]-3H-quinazolin-4-one
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|
C17H15ClN2O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0485969
|
2-[4-(2-hydroxypropan-2-yl)phenyl]-3H-quinazolin-4-one
Show/Hide
|
C17H16N2O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0468694
|
6-fluoro-2-[4-[2-(2-hydroxyethoxy)propan-2-yl]phenyl]-3H-quinazolin-4-one
Show/Hide
|
C19H19FN2O3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0468690
|
6-fluoro-2-[4-[2-(2-methoxyethoxy)propan-2-yl]phenyl]-3H-quinazolin-4-one
Show/Hide
|
C20H21FN2O3
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0434855
|
5-fluoro-2-[4-(2-hydroxypropan-2-yl)phenyl]-3H-quinazolin-4-one
Show/Hide
|
C17H15FN2O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0458122
|
8-fluoro-2-[4-(2-hydroxypropan-2-yl)phenyl]-3H-quinazolin-4-one
Show/Hide
|
C17H15FN2O2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0567329
|
6,8-difluoro-2-[4-(1-methylpiperidin-4-yl)phenyl]-3H-quinazolin-4-one;2,2,2-trifluoroacetic acid
Show/Hide
|
C22H20F5N3O3
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0458124
|
6,8-difluoro-2-(4-piperidin-4-ylphenyl)-3H-quinazolin-4-one;hydrochloride
Show/Hide
|
C19H18ClF2N3O
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0468688
|
6-chloro-2-[4-(2-hydroxypropan-2-yl)phenyl]-3H-quinazolin-4-one
Show/Hide
|
C17H15ClN2O2
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0485971
|
5,8-difluoro-2-[4-(2-hydroxypropan-2-yl)phenyl]-3H-quinazolin-4-one
Show/Hide
|
C17H14F2N2O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0481805
|
2-[4-(2-hydroxypropan-2-yl)phenyl]-8-methoxy-3H-quinazolin-4-one
Show/Hide
|
C18H18N2O3
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0434856
|
5-chloro-2-[4-(2-hydroxypropan-2-yl)phenyl]-3H-quinazolin-4-one
Show/Hide
|
C17H15ClN2O2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0040799
|
2-(4-Methoxy-phenyl)-quinazolin-4-ol
Show/Hide
|
C15H12N2O2
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0124674
|
(2Z)-2-[[4-[4-(1H-benzimidazol-2-yl)piperazine-1-carbonyl]phenyl]methylidene]-3-oxo-1-benzofuran-7-carboxamide
Show/Hide
|
C28H23N5O4
|
1
|
| 1 |
IC50 = 198 nM
|
|
|
|
CP0092236
|
2-Phenyl-3H-quinazolin-4-one
Show/Hide
|
C14H10N2O
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
|
CP0478961
|
tert-butyl 7-[2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoyl]-2,7-diazaspiro[4.4]nonane-2-carboxylate
Show/Hide
|
C28H31FN4O4
|
1
|
| 1 |
IC50 = 576 nM
|
|
|
|
CP0468686
|
2-(1,3-benzodioxol-5-yl)-3H-quinazolin-4-one
Show/Hide
|
C15H10N2O3
|
1
|
| 1 |
IC50 = 620 nM
|
|
|
|
CP0481806
|
6-fluoro-2-[5-(2-hydroxypropan-2-yl)pyridin-2-yl]-3H-quinazolin-4-one
Show/Hide
|
C16H14FN3O2
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0389557
|
tert-butyl 2-[2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoyl]-2,8-diazaspiro[4.5]decane-8-carboxylate
Show/Hide
|
C29H33FN4O4
|
1
|
| 1 |
IC50 = 953 nM
|
|
|
|
CP0120515
|
4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbonyl]-4-fluorophenyl}methyl)-1,2-dihydrophthalazin-1-one
Show/Hide
|
C24H23FN4O3
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0481994
|
tert-butyl 9-[2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoyl]-3,9-diazaspiro[5.5]undecane-3-carboxylate
Show/Hide
|
C30H35FN4O4
|
1
|
| 1 |
IC50 = 2800 nM
|
|
|
|
CP0051608
|
3-(8-methyl-4-oxo-3H-quinazolin-2-yl)propanoic acid
Show/Hide
|
C12H12N2O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0113876
|
3-(4-oxo-3H-quinazolin-2-yl)propanoic acid
Show/Hide
|
C11H10N2O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0113877
|
4-amino-N-quinolin-8-ylbenzamide
Show/Hide
|
C16H13N3O
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0134484
|
(2Z)-3-oxo-2-[[4-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazine-7-carbonyl]phenyl]methylidene]-1-benzofuran-7-carboxamide
Show/Hide
|
C23H16F3N5O4
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
