| Compound ID |
Compound Name |
Compound Formula |
|
CP0389521
|
(1S,2S,4S,5R,6S)-2-amino-4-[(2-hydroxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Show/Hide
|
C15H16N2O6
|
2
|
| 1 |
EC50 = 0.17 nM
|
|
|
| 2 |
Ki = 1.79 nM
|
|
|
|
CP0356641
|
(1S,2S,4S,5R,6S)-2-amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Show/Hide
|
C16H18N2O6
|
2
|
| 1 |
EC50 = 0.47 nM
|
|
|
| 2 |
Ki = 0.927 nM
|
|
|
|
CP0454448
|
(1S,2S,4S,5R,6S)-2-amino-4-[(3-hydroxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Show/Hide
|
C15H16N2O6
|
2
|
| 1 |
EC50 = 0.71 nM
|
|
|
| 2 |
Ki = 2.27 nM
|
|
|
|
CP0447261
|
(1S,2S,4S,5R,6S)-2-amino-4-[(3-chlorobenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Show/Hide
|
C15H15ClN2O5
|
2
|
| 1 |
EC50 = 0.82 nM
|
|
|
| 2 |
Ki = 0.47 nM
|
|
|
|
CP0465824
|
(1S,2S,4S,5R,6S)-2-amino-4-[(3-fluorobenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Show/Hide
|
C15H15FN2O5
|
2
|
| 1 |
EC50 = 2 nM
|
|
|
| 2 |
Ki = 2.11 nM
|
|
|
|
CP0396672
|
(1S,2S,4S,5R,6S)-2-amino-4-[(4-hydroxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Show/Hide
|
C15H16N2O6
|
2
|
| 1 |
EC50 = 2.12 nM
|
|
|
| 2 |
Ki = 9.34 nM
|
|
|
|
CP0476634
|
(1S,2S,4S,5R,6S)-2-amino-4-[(4-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Show/Hide
|
C16H18N2O6
|
2
|
| 1 |
EC50 = 2.44 nM
|
|
|
| 2 |
Ki = 4.56 nM
|
|
|
|
CP0447263
|
(1S,2S,4S,5R,6S)-2-amino-4-benzamidobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Show/Hide
|
C15H16N2O5
|
2
|
| 1 |
EC50 = 4.96 nM
|
|
|
| 2 |
Ki = 6.75 nM
|
|
|
|
CP0447264
|
(1S,2S,4S,5R,6S)-2-amino-4-[(2-chlorobenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Show/Hide
|
C15H15ClN2O5
|
2
|
| 1 |
EC50 = 4.96 nM
|
|
|
| 2 |
Ki = 27.4 nM
|
|
|
|
CP0396668
|
(1S,2S,4S,5R,6S)-2-amino-4-[(2-fluorobenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Show/Hide
|
C15H15FN2O5
|
2
|
| 1 |
EC50 = 5.1 nM
|
|
|
| 2 |
Ki = 5.79 nM
|
|
|
|
CP0396670
|
(1S,2S,4S,5R,6S)-2-amino-4-[(4-chlorobenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Show/Hide
|
C15H15ClN2O5
|
2
|
| 1 |
EC50 = 5.15 nM
|
|
|
| 2 |
Ki = 2.29 nM
|
|
|
|
CP0390069
|
(1S,2S,4S,5R,6S)-2-amino-4-[(4-fluorobenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Show/Hide
|
C15H15FN2O5
|
2
|
| 1 |
EC50 = 6.6 nM
|
|
|
| 2 |
Ki = 4.34 nM
|
|
|
|
CP0465823
|
(1S,2S,4S,5R,6S)-2-amino-4-[(2-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Show/Hide
|
C16H18N2O6
|
2
|
| 1 |
EC50 = 7.15 nM
|
|
|
| 2 |
Ki = 23.2 nM
|
|
|
|
CP0390062
|
(1S,2S,4S,5R,6S)-2,4-diaminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Show/Hide
|
C8H12N2O4
|
2
|
| 1 |
EC50 = 24.9 nM
|
|
|
| 2 |
Ki = 284 nM
|
|
|
|
CP0076675
|
(1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Show/Hide
|
C8H11NO4
|
2
|
| 1 |
EC50 = 27.9 nM
|
|
|
| 2 |
Ki = 107 nM
|
|
|
|
CP0448123
|
2-[(4-fluorophenoxy)methyl]-5-(4-fluorophenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
Show/Hide
|
C19H15F2N3O2
|
1
|
| 1 |
EC50 = 34 nM
|
|
|
|
CP0002355
|
(2S)-2-aminopentanedioic acid
Show/Hide
|
C5H9NO4
|
2
|
| 1 |
EC50 = 60 nM
|
|
|
| 2 |
Ki = 57.54 nM
|
|
|
|
CP0420566
|
5-(4-fluorophenyl)-2-(phenoxymethyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
Show/Hide
|
C19H16FN3O2
|
1
|
| 1 |
EC50 = 74 nM
|
|
|
|
CP0441053
|
10'-(6-fluoropyridin-3-yl)-6'-methylspiro[cyclopropane-1,7'-pyrido[2,3-d][2]benzazepine]-5'-one
Show/Hide
|
C21H16FN3O
|
1
|
| 1 |
EC50 < 100 nM
|
|
|
|
CP0519317
|
9'-(6-fluoropyridin-3-yl)-2'-(methoxymethyl)-5'-methylspiro[cyclopropane-1,6'-pyrazolo[3,4-d][2]benzazepine]-4'-one
Show/Hide
|
C21H19FN4O2
|
1
|
| 1 |
EC50 < 100 nM
|
|
|
|
CP0548390
|
10'-(6-fluoropyridin-3-yl)-3'-methoxy-6'-methylspiro[cyclopropane-1,7'-pyrido[2,3-d][2]benzazepine]-5'-one
Show/Hide
|
C22H18FN3O2
|
1
|
| 1 |
EC50 < 100 nM
|
|
|
|
CP0571040
|
10'-(5-fluoropyridin-2-yl)-6'-methylspiro[cyclopropane-1,7'-pyrido[2,3-d][2]benzazepine]-5'-one
Show/Hide
|
C21H16FN3O
|
1
|
| 1 |
EC50 < 100 nM
|
|
|
|
CP0576115
|
9'-(6-fluoropyridin-3-yl)-5'-methylspiro[cyclobutane-1,6'-pyrrolo[1,2-a][1,4]benzodiazepine]-4'-one
Show/Hide
|
C21H18FN3O
|
1
|
| 1 |
EC50 < 100 nM
|
|
|
|
CP0577136
|
10-(6-fluoropyridin-3-yl)-3-methoxy-6-methyl-7H-pyrido[2,3-d][2]benzazepin-5-one
Show/Hide
|
C20H16FN3O2
|
1
|
| 1 |
EC50 < 100 nM
|
|
|
|
CP0873237
|
9-(5-fluoropyridin-2-yl)-2-(methoxymethyl)-5-methyl-5,6-dihydrobenzo[c]pyrazolo[4,3-e]azepin-4(2H)-one
Show/Hide
|
C19H17FN4O2
|
1
|
| 1 |
EC50 <= 100 nM
|
|
|
|
CP0958428
|
2-ethyl-5-methyl-9-(2-methylpyridin-3-yl)-5,6-dihydrobenzo[c]pyrazolo[4,3-e]azepin-4(2H)-one
Show/Hide
|
C20H20N4O
|
1
|
| 1 |
EC50 <= 100 nM
|
|
|
|
CP0395096
|
5-(4-methylphenyl)-2-(phenoxymethyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
Show/Hide
|
C20H19N3O2
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0385921
|
(1S,2S,4S,5R,6S)-4-acetamido-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Show/Hide
|
C10H14N2O5
|
2
|
| 1 |
EC50 = 193 nM
|
|
|
| 2 |
Ki = 177 nM
|
|
|
|
CP0395113
|
5-(4-fluorophenyl)-2-(pyridin-2-yloxymethyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
Show/Hide
|
C18H15FN4O2
|
1
|
| 1 |
EC50 = 290 nM
|
|
|
|
CP0519556
|
(1S,2S,4S,5R,6S)-2-amino-4-(benzylamino)bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Show/Hide
|
C15H18N2O4
|
2
|
| 1 |
EC50 = 356 nM
|
|
|
| 2 |
Ki = 1070 nM
|
|
|
|
CP0448124
|
5-(4-fluorophenyl)-2-(phenoxymethyl)-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one
Show/Hide
|
C20H18FN3O2
|
1
|
| 1 |
EC50 = 540 nM
|
|
|
|
CP0326353
|
7-[[(1S,2S)-2-(4-chlorophenyl)cyclopropyl]methoxy]-3-(cyclopropylmethyl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine
Show/Hide
|
C21H19ClF3N3O
|
1
|
| 1 |
EC50 = 890 nM
|
|
|
|
CP0395090
|
5-(4-fluorophenyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
Show/Hide
|
C19H16FN3O2
|
1
|
| 1 |
EC50 = 3390 nM
|
|
|
|
CP0099614
|
5-(5-fluoropyridin-2-yl)-2-(phenoxymethyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
Show/Hide
|
C18H15FN4O2
|
1
|
| 1 |
EC50 = 6760 nM
|
|
|
|
CP0077643
|
5-methyl-2-(phenoxymethyl)-6,7-dihydro-[1,3]thiazolo[5,4-c]pyridin-4-one
Show/Hide
|
C14H14N2O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0133913
|
7-(benzyloxy)-2,3-dihydro-4H-chromen-4-one
Show/Hide
|
C16H14O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0379848
|
7-(phenoxymethyl)chroman-4-one
Show/Hide
|
C16H14O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0379852
|
2-(2-phenylethynyl)-5,6-dihydro-4H-1,3-benzothiazol-7-one
Show/Hide
|
C15H11NOS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0390064
|
(1S,2S,4S,5R,6S)-2-amino-4-[(2-cyclohexylacetyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Show/Hide
|
C16H24N2O5
|
3
|
| 1 |
EC50 > 25000 nM
|
|
|
| 2 |
IC50 > 25000 nM
|
|
|
| 3 |
Ki = 425 nM
|
|
|
|
CP0396669
|
(1S,2S,4S,5R,6S)-2-amino-4-(cyclohexanecarbonylamino)bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Show/Hide
|
C15H22N2O5
|
3
|
| 1 |
EC50 > 25000 nM
|
|
|
| 2 |
IC50 = 9990 nM
|
|
|
| 3 |
Ki = 757 nM
|
|
|
|
CP0454449
|
(1S,2S,4S,5R,6S)-2-amino-4-(3-phenylpropanoylamino)bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Show/Hide
|
C17H20N2O5
|
3
|
| 1 |
EC50 > 25000 nM
|
|
|
| 2 |
IC50 = 2050 nM
|
|
|
| 3 |
Ki = 281 nM
|
|
|
