Brief Information of the Cell Line and Protein
Cell Line ID: CL001008 , CHO-A3
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0214
Protein ID: PT01173 , Histamine H3 receptor
Gene Name HRH3
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID Q9QYN8
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL001008  Protein ID: PT01173
 
Compound ID Compound Name Compound Formula
CP0160985
4-[4-[(2S)-2-methyl-3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
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C19H25N3O2
 1
1
Ki = 4 nM
   TI
   LI
   LO
   TS
CP0397274
4-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
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C18H23N3O2
 1
1
Ki = 9 nM
   TI
   LI
   LO
   TS
CP0436424
4-methoxy-2-(methoxymethyl)-5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
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C21H29N3O4
 1
1
Ki = 13 nM
   TI
   LI
   LO
   TS
CP0160988
2-(methoxymethyl)-5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
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C20H27N3O3
 1
1
Ki = 14 nM
   TI
   LI
   LO
   TS
CP0475460
5-methoxy-2-(methoxymethyl)-4-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyridazin-3-one
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C21H29N3O4
 1
1
Ki = 19 nM
   TI
   LI
   LO
   TS
CP0410256
4-[4-[(2S)-2-methyl-3-piperidin-1-ylpropoxy]phenyl]-1H-pyridazin-6-one
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C19H25N3O2
 1
1
Ki = 34 nM
   TI
   LI
   LO
   TS
CP0385309
4-[4-[(2R)-2-methyl-3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
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C19H25N3O2
 1
1
Ki = 43 nM
   TI
   LI
   LO
   TS
CP0542354
4-methoxy-5-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-1H-pyridazin-6-one
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C19H25N3O3
 1
1
Ki = 62 nM
   TI
   LI
   LO
   TS
CP0450518
4-[4-[(2R)-2-methyl-3-piperidin-1-ylpropoxy]phenyl]-1H-pyridazin-6-one
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C19H25N3O2
 1
1
Ki = 131 nM
   TI
   LI
   LO
   TS