| Compound ID |
Compound Name |
Compound Formula |
|
CP0967056
|
methyl(3R,5S)-3,5-dimethyl-4-[3-[6-[(3R)-3-methylpiperazin-1-yl]-3-pyridyl]-1H-pyrazolo[4,3-d]pyrimidin-5-yl]piperazine-1-carboxylate
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|
C23H31N9O2
|
1
|
| 1 |
IC50 = 0.85 nM
|
|
|
|
CP0970051
|
methyl(3R,5S)-3,5-dimethyl-4-[3-[4-(4-methylpiperazin-1-yl)phenyl]-1H-pyrazolo[4,3-d]pyrimidin-5-yl]piperazine-1-carboxylate
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|
C24H32N8O2
|
1
|
| 1 |
IC50 = 0.98 nM
|
|
|
|
CP0950697
|
[(3R,5S)-3,5-dimethyl-4-[3-[6-[(3R)-3-methylpiperazin-1-yl]-3-pyridyl]-1H-pyrazolo[4,3-d]pyrimidin-5-yl]piperazin-1-yl]-pyrrolidin-1-yl-methanone
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|
C26H36N10O
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0965080
|
methyl(3R,5S)-3,5-dimethyl-4-[3-[6-(4-methylpiperazin-1-yl)-3-pyridyl]-1H-pyrazolo[4,3-d]pyrimidin-5-yl]piperazine-1-carboxylate
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|
C23H31N9O2
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0965937
|
methyl(3R,5S)-4-[3-[3-fluoro-4-(4-methylpiperazin-1-yl)phenyl]-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3,5-dimethyl-piperazine-1-carboxylate
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|
C24H31FN8O2
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0964932
|
5-[(2S,6R)-2,6-dimethyl-1-piperidyl]-3-[6-[(3R)-3-methylpiperazin-1-yl]-3-pyridyl]-1H-pyrazolo[4,3-d]pyrimidine
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|
C22H30N8
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0970645
|
ethyl(3R,5S)-3,5-dimethyl-4-[3-[6-[(3R)-3-methylpiperazin-1-yl]-3-pyridyl]-1H-pyrazolo[4,3-d]pyrimidin-5-yl]piperazine-1-carboxylate
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|
C24H33N9O2
|
1
|
| 1 |
IC50 = 4.9 nM
|
|
|
|
CP0951945
|
(3R,5S)-N,N,3,5-tetramethyl-4-[3-[6-[(3R)-3-methylpiperazin-1-yl]-3-pyridyl]-1H-pyrazolo[4,3-d]pyrimidin-5-yl]piperazine-1-carboxamide
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|
C24H34N10O
|
1
|
| 1 |
IC50 = 6.4 nM
|
|
|
|
CP0967055
|
1-[(3R,5S)-3,5-dimethyl-4-[3-[6-[(3R)-3-methylpiperazin-1-yl]-3-pyridyl]-1H-pyrazolo[4,3-d]pyrimidin-5-yl]piperazin-1-yl]-2-methoxy-ethanone
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|
C24H33N9O2
|
1
|
| 1 |
IC50 = 7.3 nM
|
|
|
|
CP0965079
|
1-[(3R,5S)-3,5-dimethyl-4-[3-[6-[(3R)-3-methylpiperazin-1-yl]-3-pyridyl]-1H-pyrazolo[4,3-d]pyrimidin-5-yl]piperazin-1-yl]-2-methyl-propan-1-one
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|
C25H35N9O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0967053
|
3-[6-[(3R)-3-methylpiperazin-1-yl]-3-pyridyl]-5-(2-methyl-1-piperidyl)-1H-pyrazolo[4,3-d]pyrimidine
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|
C21H28N8
|
1
|
| 1 |
IC50 = 8.1 nM
|
|
|
|
CP0128561
|
1-[4-[5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl]piperazine
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|
C24H27N3O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0967054
|
(3R,5S)-3,5-dimethyl-4-[3-[6-[(3R)-3-methylpiperazin-1-yl]-3-pyridyl]-1H-pyrazolo[4,3-d]pyrimidin-5-yl]morpholine
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|
C21H28N8O
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0143998
|
1-[4-[6-methyl-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl]piperazine
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|
C25H29N3O3
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0965295
|
3-[6-[(3R)-3-methylpiperazin-1-yl]-3-pyridyl]-5-(1-piperidyl)-1H-pyrazolo[4,3-d]pyrimidine
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|
C20H26N8
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0968823
|
3-[6-[(3R)-3-methylpiperazin-1-yl]-3-pyridyl]-5-(1-piperidyl)-1H-pyrazolo[3,4-c]pyridine
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|
C21H27N7
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0970285
|
3-[6-[(3R)-3-methylpiperazin-1-yl]-3-pyridyl]-5-(1-piperidyl)-1H-pyrazolo[4,3-b]pyridine
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|
C21H27N7
|
1
|
| 1 |
IC50 = 95 nM
|
|
|
|
CP0970644
|
5-[(2R,6S)-2,6-dimethylpiperazin-1-yl]-3-[6-[(3R)-3-methylpiperazin-1-yl]-3-pyridyl]-1H-pyrazolo[4,3-d]pyrimidine
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|
C21H29N9
|
1
|
| 1 |
IC50 = 793 nM
|
|
|
