Brief Information of the Cell Line and Protein
Cell Line ID: CL000153 , CHOP
Category Transformed cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_4702
Protein ID: PT01107 , 11-beta-hydroxysteroid dehydrogenase 1
Gene Name HSD11B1
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P28845
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000153  Protein ID: PT01107
 
Compound ID Compound Name Compound Formula
CP0523055
2,5-bis(3-bromobenzylidene)cyclopentanone
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C19H14Br2O
 1
1
IC50 = 97 nM
   TI
   LI
   LO
   TS
CP0473650
(1E,4E)-1,5-bis(2-bromophenyl)penta-1,4-dien-3-one
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C17H12Br2O
 1
1
IC50 = 115 nM
   TI
   LI
   LO
   TS
CP0397358
(2E,5E)-2,5-bis[(2-bromophenyl)methylidene]cyclopentan-1-one
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C19H14Br2O
 1
1
IC50 = 144 nM
   TI
   LI
   LO
   TS
CP0134951
2,6-bis(4-hydroxybenzylidene)cyclohexanone
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C20H18O3
 1
1
IC50 = 195 nM
   TI
   LI
   LO
   TS
CP0015639
(1E,4E)-1,5-Bis-(4-hydroxy-3-methoxy-phenyl)-penta-1,4-dien-3-one
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C19H18O5
 1
1
IC50 = 257 nM
   TI
   LI
   LO
   TS
CP0254222
2,6-Bis(4-Fluorobenzylidene)Cyclohexanone
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C20H16F2O
 1
1
IC50 = 263 nM
   TI
   LI
   LO
   TS
CP0500903
2,5-Bis(4-Fluorobenzylidene)Cyclopentanone
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C19H14F2O
 1
1
IC50 = 310 nM
   TI
   LI
   LO
   TS
CP0375977
(2E,6E)-2,6-bis[(2-bromophenyl)methylidene]cyclohexan-1-one
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C20H16Br2O
 1
1
IC50 = 346 nM
   TI
   LI
   LO
   TS
CP0229765
(1E,4E)-1,5-bis(4-fluorophenyl)penta-1,4-dien-3-one
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C17H12F2O
 1
1
IC50 = 507 nM
   TI
   LI
   LO
   TS
CP0064545
(1E,4E)-1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-3-one
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C17H14O3
 1
1
IC50 = 832 nM
   TI
   LI
   LO
   TS
CP0003494
US9187397, 1 (curcumin)
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C21H20O6
 1
1
IC50 = 4501 nM
   TI
   LI
   LO
   TS