| Compound ID |
Compound Name |
Compound Formula |
|
CP0489806
|
2-((R)-3-oxo-1-(phenylsulfonyl)-1,2,3,4-tetrahydroquinoxalin-2-yl)-N-((R)-7-(piperidin-1-ylmethyl)chroman-4-yl)acetamide
Show/Hide
|
C31H34N4O5S
|
2
|
| 1 |
IC50 = 0.12 nM
|
|
|
| 2 |
Ki = 0.19 nM
|
|
|
|
CP0439845
|
2-((R)-3-oxo-1-tosyl-1,2,3,4-tetrahydroquinoxalin-2-yl)-N-((R)-7-(piperidin-1-ylmethyl)chroman-4-yl)acetamide
Show/Hide
|
C32H36N4O5S
|
2
|
| 1 |
IC50 = 0.14 nM
|
|
|
| 2 |
Ki = 0.24 nM
|
|
|
|
CP0057919
|
(R)-N-(4-(4,5-dihydro-1H-imidazol-2-yl)phenethyl)-2-(1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)acetamide
Show/Hide
|
C27H25Cl2N5O4S
|
2
|
| 1 |
IC50 = 0.18 nM
|
|
|
| 2 |
Ki = 0.034 nM
|
|
|
|
CP0493605
|
2-[(2R)-1-(benzenesulfonyl)-3-oxo-2,4-dihydroquinoxalin-2-yl]-N-[(4R)-7-[(tert-butylamino)methyl]-3,4-dihydro-2H-chromen-4-yl]acetamide
Show/Hide
|
C30H34N4O5S
|
2
|
| 1 |
IC50 = 0.37 nM
|
|
|
| 2 |
Ki = 1.8 nM
|
|
|
|
CP0549558
|
2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)-N-((R)-7-(piperidin-1-ylmethyl)chroman-4-yl)acetamide
Show/Hide
|
C31H32Cl2N4O5S
|
2
|
| 1 |
IC50 = 0.48 nM
|
|
|
| 2 |
Ki = 0.15 nM
|
|
|
|
CP0511399
|
2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)-N-((R)-6-(piperidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl)acetamide
Show/Hide
|
C32H34Cl2N4O4S
|
2
|
| 1 |
IC50 = 0.55 nM
|
|
|
| 2 |
Ki = 0.1 nM
|
|
|
|
CP0399570
|
2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)-N-((R)-7-((methylamino)methyl)chroman-4-yl)acetamide
Show/Hide
|
C27H26Cl2N4O5S
|
2
|
| 1 |
IC50 = 0.8 nM
|
|
|
| 2 |
Ki = 1.2 nM
|
|
|
|
CP0423223
|
2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)-N-((R)-7-((isopropylamino)methyl)chroman-4-yl)acetamide
Show/Hide
|
C29H30Cl2N4O5S
|
2
|
| 1 |
IC50 = 0.86 nM
|
|
|
| 2 |
Ki = 0.7 nM
|
|
|
|
CP0440506
|
2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)-N-((R)-7-((dimethylamino)methyl)chroman-4-yl)acetamide
Show/Hide
|
C28H28Cl2N4O5S
|
2
|
| 1 |
IC50 = 1 nM
|
|
|
| 2 |
Ki = 1.7 nM
|
|
|
|
CP0528993
|
N-[(4R)-7-(aminomethyl)-3,4-dihydro-2H-chromen-4-yl]-2-[(2R)-1-(3,4-dichlorophenyl)sulfonyl-3-oxo-2,4-dihydroquinoxalin-2-yl]acetamide
Show/Hide
|
C26H24Cl2N4O5S
|
2
|
| 1 |
IC50 = 1.2 nM
|
|
|
| 2 |
Ki = 2.6 nM
|
|
|
|
CP0399569
|
2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)-N-((R)-7-((isobutylamino)methyl)chroman-4-yl)acetamide
Show/Hide
|
C30H32Cl2N4O5S
|
2
|
| 1 |
IC50 = 1.4 nM
|
|
|
| 2 |
Ki = 0.44 nM
|
|
|
|
CP0399571
|
N-[(4R)-7-[(tert-butylamino)methyl]-3,4-dihydro-2H-chromen-4-yl]-2-[(2R)-1-(3,4-dichlorophenyl)sulfonyl-3-oxo-2,4-dihydroquinoxalin-2-yl]acetamide
Show/Hide
|
C30H32Cl2N4O5S
|
2
|
| 1 |
IC50 = 1.7 nM
|
|
|
| 2 |
Ki = 1.1 nM
|
|
|
|
CP0328193
|
N-[(1R)-6-[(tert-butylamino)methyl]-1,2,3,4-tetrahydronaphthalen-1-yl]-2-[(2S)-1-[3-(trifluoromethyl)phenyl]sulfonylpiperidin-2-yl]acetamide
Show/Hide
|
C29H38F3N3O3S
|
2
|
| 1 |
IC50 = 13 nM
|
|
|
| 2 |
Ki = 23 nM
|
|
|
|
CP0423222
|
2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)-N-((R)-7-formylchroman-4-yl)acetamide
Show/Hide
|
C26H21Cl2N3O6S
|
2
|
| 1 |
IC50 = 23 nM
|
|
|
| 2 |
Ki = 57 nM
|
|
|
|
CP0457687
|
2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)-N-((R)-7-(hydroxymethyl)chroman-4-yl)acetamide
Show/Hide
|
C26H23Cl2N3O6S
|
2
|
| 1 |
IC50 = 62 nM
|
|
|
| 2 |
Ki = 86 nM
|
|
|
|
CP0457688
|
2-(1-(mesitylsulfonyl)-3-oxo-1,2,3,4-tetrahydronoxalin-2-yl)-N-(2-methoxyphenyl)acetamide
Show/Hide
|
C26H27N3O5S
|
2
|
| 1 |
IC50 > 4000 nM
|
|
|
| 2 |
Ki = 500 nM
|
|
|
