| Compound ID |
Compound Name |
Compound Formula |
|
CP0046656
|
(2S)-2-[(4-{[(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)methyl](prop-2-yn-1-yl)amino}phenyl)formamido]pentanedioic acid
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|
C24H23N5O6
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0282776
|
2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid
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|
C22H23N5O6
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0441562
|
2-{4-[(2,4-Diamino-pyrido[3,2-d]pyrimidin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid
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|
C23H23N7O5
|
1
|
| 1 |
IC50 = 1260 nM
|
|
|
|
CP0453439
|
2-{4-[(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid(8-deaza-10-propargylfolate)
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|
C23H22N6O6
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0381320
|
2-{4-[(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid(8-deaza-10-methylfolate)
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|
C21H22N6O6
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0397643
|
2-{4-[(2-Amino-4-oxo-1,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid (DDF)
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|
C21H21N5O6
|
1
|
| 1 |
IC50 = 2700 nM
|
|
|
|
CP0198010
|
2-{4-[(2-Amino-4-oxo-1,4-dihydro-pteridin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid(10-propargylfolate)
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|
C22H21N7O6
|
1
|
| 1 |
IC50 = 5500 nM
|
|
|
|
CP0428767
|
2-{4-[(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid(8-deazafolate)
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|
C20H20N6O6
|
1
|
| 1 |
IC50 = 55000 nM
|
|
|
