| Compound ID |
Compound Name |
Compound Formula |
|
CP0036757
|
3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine
Show/Hide
|
C19H24N2
|
5
|
| 1 |
IC50 = 2.6 nM
|
|
|
| 2 |
IC50 = 29 nM
|
|
|
| 3 |
Ki = 5.7 nM
|
|
|
| 4 |
Ki = 31 nM
|
|
|
| 5 |
Ki = 1300 nM
|
|
|
|
CP0407490
|
3-(2-ethynyl-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine
Show/Hide
|
C21H24N2
|
4
|
| 1 |
IC50 = 40 nM
|
|
|
| 2 |
Ki = 27 nM
|
|
|
| 3 |
Ki = 220 nM
|
|
|
| 4 |
Ki = 2400 nM
|
|
|
|
CP0401186
|
3-[11-[3-(dimethylamino)propyl]-5,6-dihydrobenzo[b][1]benzazepin-2-yl]prop-2-yn-1-ol
Show/Hide
|
C22H26N2O
|
4
|
| 1 |
IC50 = 60 nM
|
|
|
| 2 |
Ki = 35 nM
|
|
|
| 3 |
Ki = 150 nM
|
|
|
| 4 |
Ki = 2600 nM
|
|
|
|
CP0376826
|
3-[2-[3-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propoxy]propyl]-5,6-dihydrobenzo[b][1]benzazepin-11-yl]-N,N-dimethylpropan-1-amine
Show/Hide
|
C39H47N3O
|
4
|
| 1 |
IC50 = 270 nM
|
|
|
| 2 |
Ki = 330 nM
|
|
|
| 3 |
Ki = 6300 nM
|
|
|
| 4 |
Ki = 15000 nM
|
|
|
|
CP0390340
|
N,N-dimethyl-3-[2-[3-[2-(2-naphthalen-1-ylethoxy)ethoxy]propyl]-5,6-dihydrobenzo[b][1]benzazepin-11-yl]propan-1-amine
Show/Hide
|
C36H44N2O2
|
4
|
| 1 |
IC50 = 280 nM
|
|
|
| 2 |
Ki = 360 nM
|
|
|
| 3 |
Ki = 1000 nM
|
|
|
| 4 |
Ki = 6700 nM
|
|
|
|
CP0566411
|
N,N-dimethyl-3-[2-[3-(2-naphthalen-1-yloxyethoxy)propyl]-5,6-dihydrobenzo[b][1]benzazepin-11-yl]propan-1-amine
Show/Hide
|
C34H40N2O2
|
4
|
| 1 |
IC50 = 280 nM
|
|
|
| 2 |
Ki = 270 nM
|
|
|
| 3 |
Ki = 600 nM
|
|
|
| 4 |
Ki = 2700 nM
|
|
|
|
CP0401188
|
N,N-dimethyl-3-[2-[3-[2-(2-naphthalen-1-ylethoxy)ethoxy]prop-1-ynyl]-5,6-dihydrobenzo[b][1]benzazepin-11-yl]propan-1-amine
Show/Hide
|
C36H40N2O2
|
4
|
| 1 |
IC50 = 300 nM
|
|
|
| 2 |
Ki = 540 nM
|
|
|
| 3 |
Ki = 1100 nM
|
|
|
| 4 |
Ki = 5200 nM
|
|
|
|
CP0414618
|
N,N-dimethyl-3-[2-[3-(naphthalen-1-ylmethoxy)prop-1-ynyl]-5,6-dihydrobenzo[b][1]benzazepin-11-yl]propan-1-amine
Show/Hide
|
C33H34N2O
|
4
|
| 1 |
IC50 = 340 nM
|
|
|
| 2 |
Ki = 280 nM
|
|
|
| 3 |
Ki = 590 nM
|
|
|
| 4 |
Ki = 5400 nM
|
|
|
|
CP0376825
|
N,N-dimethyl-3-[2-[3-(naphthalen-1-ylmethylsulfanyloxy)prop-1-ynyl]-5,6-dihydrobenzo[b][1]benzazepin-11-yl]propan-1-amine
Show/Hide
|
C33H34N2OS
|
4
|
| 1 |
IC50 = 350 nM
|
|
|
| 2 |
Ki = 475 nM
|
|
|
| 3 |
Ki = 1100 nM
|
|
|
| 4 |
Ki = 4700 nM
|
|
|
|
CP0390344
|
N,N-dimethyl-3-[2-[3-[2-(2-naphthalen-1-yloxyethoxy)ethoxy]prop-1-ynyl]-5,6-dihydrobenzo[b][1]benzazepin-11-yl]propan-1-amine
Show/Hide
|
C36H40N2O3
|
4
|
| 1 |
IC50 = 420 nM
|
|
|
| 2 |
Ki = 450 nM
|
|
|
| 3 |
Ki = 6400 nM
|
|
|
| 4 |
Ki = 6500 nM
|
|
|
|
CP0376833
|
N,N-dimethyl-3-[2-[3-(2-naphthalen-2-yloxyethoxy)prop-1-ynyl]-5,6-dihydrobenzo[b][1]benzazepin-11-yl]propan-1-amine
Show/Hide
|
C34H36N2O2
|
4
|
| 1 |
IC50 = 440 nM
|
|
|
| 2 |
Ki = 640 nM
|
|
|
| 3 |
Ki = 1500 nM
|
|
|
| 4 |
Ki = 2000 nM
|
|
|
|
CP0055808
|
3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine
Show/Hide
|
C18H22N2
|
1
|
| 1 |
IC50 = 560 nM
|
|
|
|
CP0401187
|
N,N-dimethyl-3-[2-[3-[2-(2-naphthalen-1-ylsulfanylethoxy)ethoxy]prop-1-ynyl]-5,6-dihydrobenzo[b][1]benzazepin-11-yl]propan-1-amine
Show/Hide
|
C36H40N2O2S
|
4
|
| 1 |
IC50 = 560 nM
|
|
|
| 2 |
Ki = 500 nM
|
|
|
| 3 |
Ki = 2000 nM
|
|
|
| 4 |
Ki = 19000 nM
|
|
|
|
CP0390341
|
N,N-dimethyl-3-[2-[3-(3-naphthalen-1-yloxypropoxy)propyl]-5,6-dihydrobenzo[b][1]benzazepin-11-yl]propan-1-amine
Show/Hide
|
C35H42N2O2
|
4
|
| 1 |
IC50 = 600 nM
|
|
|
| 2 |
Ki = 620 nM
|
|
|
| 3 |
Ki = 1200 nM
|
|
|
| 4 |
Ki = 9400 nM
|
|
|
|
CP0390342
|
N,N-dimethyl-3-[2-[3-(naphthalen-1-ylmethoxy)propyl]-5,6-dihydrobenzo[b][1]benzazepin-11-yl]propan-1-amine
Show/Hide
|
C33H38N2O
|
4
|
| 1 |
IC50 = 610 nM
|
|
|
| 2 |
Ki = 290 nM
|
|
|
| 3 |
Ki = 620 nM
|
|
|
| 4 |
Ki = 5000 nM
|
|
|
|
CP0414616
|
3-[2-[3-[3-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propoxy]propoxy]propyl]-5,6-dihydrobenzo[b][1]benzazepin-11-yl]-N,N-dimethylpropan-1-amine
Show/Hide
|
C42H53N3O2
|
4
|
| 1 |
IC50 = 840 nM
|
|
|
| 2 |
Ki = 640 nM
|
|
|
| 3 |
Ki = 5900 nM
|
|
|
| 4 |
Ki = 11000 nM
|
|
|
|
CP0376828
|
N,N-dimethyl-3-[2-[3-(3-naphthalen-1-yloxypropoxy)prop-1-ynyl]-5,6-dihydrobenzo[b][1]benzazepin-11-yl]propan-1-amine
Show/Hide
|
C35H38N2O2
|
4
|
| 1 |
IC50 = 940 nM
|
|
|
| 2 |
Ki = 1200 nM
|
|
|
| 3 |
Ki = 3500 nM
|
|
|
| 4 |
Ki = 27000 nM
|
|
|
|
CP0452551
|
3-[2-[3-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propoxy]prop-1-ynyl]-5,6-dihydrobenzo[b][1]benzazepin-11-yl]-N,N-dimethylpropan-1-amine
Show/Hide
|
C39H43N3O
|
4
|
| 1 |
IC50 = 1600 nM
|
|
|
| 2 |
Ki = 1600 nM
|
|
|
| 3 |
Ki = 13000 nM
|
|
|
| 4 |
Ki = 16000 nM
|
|
|
|
CP0414617
|
3-[2-[3-[3-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propoxy]propoxy]prop-1-ynyl]-5,6-dihydrobenzo[b][1]benzazepin-11-yl]-N,N-dimethylpropan-1-amine
Show/Hide
|
C42H49N3O2
|
4
|
| 1 |
IC50 = 4100 nM
|
|
|
| 2 |
Ki = 2800 nM
|
|
|
| 3 |
Ki = 10000 nM
|
|
|
| 4 |
Ki = 11000 nM
|
|
|
|
CP0391700
|
3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-[2-[2-[2-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-methylamino]ethoxy]ethoxy]ethyl]-N-methylpropan-1-amine
Show/Hide
|
C42H54N4O2
|
1
|
| 1 |
IC50 = 4800 nM
|
|
|
|
CP0376830
|
N,N-dimethyl-3-[2-[3-(2-naphthalen-1-yloxyethoxy)prop-1-ynyl]-5,6-dihydrobenzo[b][1]benzazepin-11-yl]propan-1-amine
Show/Hide
|
C34H36N2O2
|
4
|
| 1 |
IC50 = 4800 nM
|
|
|
| 2 |
Ki = 1800 nM
|
|
|
| 3 |
Ki = 3500 nM
|
|
|
| 4 |
Ki = 8000 nM
|
|
|
|
CP0449275
|
3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-[2-[2-[2-[2-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-methylamino]ethoxy]ethoxy]ethoxy]ethyl]-N-methylpropan-1-amine
Show/Hide
|
C44H58N4O3
|
1
|
| 1 |
IC50 = 5500 nM
|
|
|
|
CP0478378
|
3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-[2-[2-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-methylamino]ethoxy]ethyl]-N-methylpropan-1-amine
Show/Hide
|
C40H50N4O
|
1
|
| 1 |
IC50 = 6000 nM
|
|
|
|
CP0506008
|
N-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-2-[2-[2-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-methylamino]-2-oxoethoxy]ethoxy]-N-methylacetamide
Show/Hide
|
C42H50N4O4
|
1
|
| 1 |
IC50 = 46000 nM
|
|
|
