General Information of the Compound
Compound ID
CP0969400
Compound Name
(2S)-2-amino-6-[[4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-oxo-pyrimidin-5-yl]methylamino]hexanoic acid
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Structure
Formula
C16H27N5O6
Molecular Weight
385.421
Canonical SMILES
Nc1nc(=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)cc1CNCCCC[C@H](N)C(=O)O
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InChI
InChI=1S/C16H27N5O6/c17-10(15(24)25)3-1-2-4-19-6-9-7-21(16(26)20-14(9)18)13-5-11(23)12(8-22)27-13/h7,10-13,19,22-23H,1-6,8,17H2,(H,24,25)(H2,18,20,26)/t10-,11-,12+,13+/m0/s1
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InChIKey
RIYMDHNAUKQPEJ-WUHRBBMRSA-N
Physicochemical Property
logP
-1.862
Rotatable Bonds
10
Heavy Atom Count
27
Polar Areas
185.95
Hydrogen Bond Donor Count
6
Hydrogen Bond Acceptor Count
10
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 168279702
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02598, DNA (cytosine-5)-methyltransferase 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 2700 nM
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