General Information of the Compound
Compound ID
CP0961354
Compound Name
8-amino-2-(3,4-dimethoxyphenyl)-N-(2-(4-(4-(2-methoxyethoxy)phenyl)piperazin-1-yl)ethyl)imidazo [1,2-a]pyridine-6-carboxamide dihydrochloride
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Structure
Formula
C31H40Cl2N6O5
Molecular Weight
647.604
Canonical SMILES
COCCOc1ccc(N2CCN(CCNC(=O)c3cc(N)c4nc(-c5ccc(OC)c(OC)c5)cn4c3)CC2)cc1.Cl.Cl
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InChI
InChI=1S/C31H38N6O5.2ClH/c1-39-16-17-42-25-7-5-24(6-8-25)36-14-12-35(13-15-36)11-10-33-31(38)23-18-26(32)30-34-27(21-37(30)20-23)22-4-9-28(40-2)29(19-22)41-3;;/h4-9,18-21H,10-17,32H2,1-3H3,(H,33,38);2*1H
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InChIKey
FOAKCZBQSKGGJI-UHFFFAOYSA-N
Physicochemical Property
logP
4.0215
Rotatable Bonds
12
Heavy Atom Count
44
Polar Areas
115.82
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
10
Complexity
44

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 145963553
ChEMBL ID
CHEMBL4125868
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS