General Information of the Compound
Compound ID
CP0953877
Compound Name
SID846109
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Formula
C16H17N5OS
Molecular Weight
327.413
Canonical SMILES
CSc1nc2nc3c(c(O)n2n1)CN(Cc1ccccc1)CC3
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InChI
InChI=1S/C16H17N5OS/c1-23-16-18-15-17-13-7-8-20(9-11-5-3-2-4-6-11)10-12(13)14(22)21(15)19-16/h2-6,22H,7-10H2,1H3
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InChIKey
LJTDWXNIVIYEKN-UHFFFAOYSA-N
Physicochemical Property
logP
2.1101
Rotatable Bonds
3
Heavy Atom Count
23
Polar Areas
66.55
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
23

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL1444408
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 707.95 nM
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