General Information of the Compound
Compound ID
CP0932397
Compound Name
2-(4-Chlorophenyl)-2-(2-dimethylaminoethyl)-1,2-dihydro-3-oxa-phenanthren-4-one oxalate
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Structure
Formula
C25H24ClNO6
Molecular Weight
469.921
Canonical SMILES
CN(C)CCC1(c2ccc(Cl)cc2)Cc2ccc3ccccc3c2C(=O)O1.O=C(O)C(=O)O
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InChI
InChI=1S/C23H22ClNO2.C2H2O4/c1-25(2)14-13-23(18-9-11-19(24)12-10-18)15-17-8-7-16-5-3-4-6-20(16)21(17)22(26)27-23;3-1(4)2(5)6/h3-12H,13-15H2,1-2H3;(H,3,4)(H,5,6)
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InChIKey
NGYAIUPWRLHJKJ-UHFFFAOYSA-N
Physicochemical Property
logP
4.2089
Rotatable Bonds
4
Heavy Atom Count
33
Polar Areas
104.14
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 49799324
ChEMBL ID
CHEMBL1173106
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02463, Urotensin-2 receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
EC50 = 1148.15 nM
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